STRINGSTRING
SPAG16 SPAG16 POLR2D POLR2D POLR2I POLR2I GTF2F1 GTF2F1 TAF15 TAF15 POLR2C POLR2C GTF2A2 GTF2A2 TAF3 TAF3 GTF2B GTF2B TAF12 TAF12 MNAT1 MNAT1 UPK3BL1-2 UPK3BL1-2 CCNH CCNH TAF1 TAF1 GTF2A1 GTF2A1 UPK3BL1 UPK3BL1 ENSPTRP00000088994 ENSPTRP00000088994 ENSPTRP00000088111 ENSPTRP00000088111 ENSPTRP00000088036 ENSPTRP00000088036 ERCC3 ERCC3 GTF2H5 GTF2H5 TAF9 TAF9 CK820_G0005641 CK820_G0005641 POLR2J POLR2J TAF7L TAF7L GTF2H1 GTF2H1 C11H11orf88 C11H11orf88 ERCC2 ERCC2 ENSPTRP00000078721 ENSPTRP00000078721 GTF2A2-2 GTF2A2-2 ENSPTRP00000076134 ENSPTRP00000076134 POLR2H POLR2H CDK7 CDK7 POLR2E POLR2E POLR2G POLR2G ENSPTRP00000069669 ENSPTRP00000069669 POLR2L POLR2L LINC02218 LINC02218 ENSPTRP00000064797 ENSPTRP00000064797 TAF5 TAF5 TAF6 TAF6 TAF4B TAF4B POLR2F POLR2F TAF10 TAF10 TAF4 TAF4 TBP TBP TAF2 TAF2 GTF2H3 GTF2H3 TAF9B TAF9B POLR2A POLR2A GTF2F2 GTF2F2 GTF2E2 GTF2E2 TAF13 TAF13 POLR2K POLR2K TBPL1 TBPL1 TAF11 TAF11 GTF2H4 GTF2H4 GTF2H2C GTF2H2C POLR2B POLR2B GTF2E1 GTF2E1 CK820_G0037203 CK820_G0037203
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SPAG16Sperm associated antigen 16. (631 aa)
POLR2DPolymerase (RNA) II (DNA directed) polypeptide D. (142 aa)
POLR2IDNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (125 aa)
GTF2F1Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (517 aa)
TAF15TAF15 isoform 12. (603 aa)
POLR2CPolymerase (RNA) II (DNA directed) polypeptide C, 33kDa. (275 aa)
GTF2A2Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family. (109 aa)
TAF3TATA-box binding protein associated factor 3. (931 aa)
GTF2BGeneral transcription factor IIB. (310 aa)
TAF12TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa. (213 aa)
MNAT1CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (309 aa)
UPK3BL1-2Uroplakin 3B like 1. (275 aa)
CCNHCCNH isoform 1; Belongs to the cyclin family. (325 aa)
TAF1Transcription initiation factor TFIID subunit. (1927 aa)
GTF2A1General transcription factor IIA, 1, 19/37kDa. (366 aa)
UPK3BL1Uroplakin-3b-like protein 1 isoform X2. (263 aa)
ENSPTRP00000088994annotation not available (135 aa)
ENSPTRP00000088111annotation not available (134 aa)
ENSPTRP00000088036annotation not available (243 aa)
ERCC3ERCC excision repair 3, TFIIH core complex helicase subunit. (782 aa)
GTF2H5General transcription factor IIH, polypeptide 5. (71 aa)
TAF9TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa. (255 aa)
CK820_G0005641GTF2H1 isoform 5. (136 aa)
POLR2JPOLR2J2 isoform 2. (159 aa)
TAF7LTATA-box binding protein associated factor 7 like. (457 aa)
GTF2H1General transcription factor IIH, polypeptide 1, 62kDa. (551 aa)
C11H11orf88C11orf88 isoform 2. (196 aa)
ERCC2ERCC excision repair 2, TFIIH core complex helicase subunit. (760 aa)
ENSPTRP00000078721annotation not available (91 aa)
GTF2A2-2General transcription factor IIA subunit 2. (72 aa)
ENSPTRP00000076134annotation not available (211 aa)
POLR2HDNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (196 aa)
CDK7Cyclin-dependent kinase 7; Belongs to the protein kinase superfamily. (346 aa)
POLR2EPolymerase (RNA) II (DNA directed) polypeptide E, 25kDa. (210 aa)
POLR2GPOLR2G isoform 2. (64 aa)
ENSPTRP00000069669annotation not available (324 aa)
POLR2LRNA polymerase II subunit L. (67 aa)
LINC02218Long intergenic non-protein coding RNA 2218. (198 aa)
ENSPTRP00000064797annotation not available (144 aa)
TAF5TATA-box binding protein associated factor 5. (803 aa)
TAF6TATA-box binding protein associated factor 6. (714 aa)
TAF4BTAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa. (862 aa)
POLR2FRNA polymerase II subunit F. (158 aa)
TAF10Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family. (218 aa)
TAF4TATA-box binding protein associated factor 4. (1083 aa)
TBPTBP isoform 1. (336 aa)
TAF2TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDa. (1199 aa)
GTF2H3General transcription factor IIH, polypeptide 3, 34kDa. (308 aa)
TAF9BTAF9B isoform 1. (251 aa)
POLR2ADNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1960 aa)
GTF2F2General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity. (249 aa)
GTF2E2Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase. (291 aa)
TAF13TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa. (124 aa)
POLR2KPolymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa. (58 aa)
TBPL1TATA box-binding protein-like protein 1. (186 aa)
TAF11TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 28kDa. (211 aa)
GTF2H4General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II. In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFII [...] (462 aa)
GTF2H2CGeneral transcription factor IIH subunit. (395 aa)
POLR2BDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1174 aa)
GTF2E1General transcription factor IIE, polypeptide 1, alpha 56kDa. (439 aa)
CK820_G0037203TAF4 isoform 5. (635 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.