STRINGSTRING
APOE APOE TFAP2E TFAP2E CITED4 CITED4 PITX3 PITX3 YEATS4 YEATS4 YY1 YY1 UBE2I UBE2I WWOX WWOX KCTD1 KCTD1 ATAD2B ATAD2B MYBL2 MYBL2 TFAP2C TFAP2C EP300 EP300 KIT KIT PITX2 PITX2 PITX1 PITX1 DEK DEK TFAP2D TFAP2D ESR1 ESR1 NPM2 NPM2 ATAD2 ATAD2 CITED1 CITED1 ENSPTRP00000048563 ENSPTRP00000048563 ZFP42 ZFP42 CK820_G0042350 CK820_G0042350 ENSPTRP00000054347 ENSPTRP00000054347 NPM1-2 NPM1-2 CDKN1A CDKN1A ENSPTRP00000066329 ENSPTRP00000066329 HSPD1 HSPD1 ENSPTRP00000064971 ENSPTRP00000064971 ENSPTRP00000066065 ENSPTRP00000066065 LOC743115 LOC743115 NOP2 NOP2 NPM1 NPM1 EGFR EGFR ERBB2 ERBB2 ENSPTRP00000069907 ENSPTRP00000069907 ENSPTRP00000074371 ENSPTRP00000074371 ENSPTRP00000074499 ENSPTRP00000074499 LOC737257 LOC737257 CREBBP CREBBP MYC MYC KDM5B KDM5B ENSPTRP00000075745 ENSPTRP00000075745 TFAP2B TFAP2B TGFA TGFA CITED2 CITED2 LOC467037 LOC467037 SUMO1-2 SUMO1-2 ENSPTRP00000085085 ENSPTRP00000085085 ENSPTRP00000085517 ENSPTRP00000085517 SUMO1-3 SUMO1-3 ENSPTRP00000085903 ENSPTRP00000085903 ENSPTRP00000087196 ENSPTRP00000087196 TFAP2A TFAP2A ENSPTRP00000088520 ENSPTRP00000088520 CGA CGA SUMO1 SUMO1 CK820_G0006425 CK820_G0006425 LOC107973292 LOC107973292
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
APOEApolipoprotein E; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density [...] (317 aa)
TFAP2ETranscription factor AP-2 epsilon. (442 aa)
CITED4Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 4. (184 aa)
PITX3Homeobox protein. (302 aa)
YEATS4YEATS domain containing 4. (227 aa)
YY1YY1 transcription factor. (414 aa)
UBE2IUbiquitin conjugating enzyme E2 I; Belongs to the ubiquitin-conjugating enzyme family. (198 aa)
WWOXWW domain containing oxidoreductase. (414 aa)
KCTD1KCTD1 isoform 1. (865 aa)
ATAD2BATPase family, AAA domain containing 2B. (1458 aa)
MYBL2V-myb myeloblastosis viral oncogene homolog (Avian)-like 2. (699 aa)
TFAP2CTranscription factor AP-2 gamma. (450 aa)
EP300E1A binding protein p300. (2175 aa)
KITMast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (972 aa)
PITX2Homeobox protein. (324 aa)
PITX1Homeobox protein. (314 aa)
DEKDEK proto-oncogene. (374 aa)
TFAP2DTranscription factor AP-2 delta. (452 aa)
ESR1Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (595 aa)
NPM2Nucleophosmin/nucleoplasmin 2. (213 aa)
ATAD2ATAD2 isoform 1. (1391 aa)
CITED1Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 1. (219 aa)
ENSPTRP00000048563annotation not available (152 aa)
ZFP42ZFP42 zinc finger protein. (310 aa)
CK820_G0042350CGB7 isoform 1. (133 aa)
ENSPTRP00000054347annotation not available (161 aa)
NPM1-2NPM1 isoform 5. (306 aa)
CDKN1ACyclin-dependent kinase inhibitor 1A (P21, Cip1). (276 aa)
ENSPTRP00000066329annotation not available (241 aa)
HSPD1Heat shock 60kDa protein 1 (Chaperonin); Belongs to the chaperonin (HSP60) family. (598 aa)
ENSPTRP00000064971annotation not available (587 aa)
ENSPTRP00000066065annotation not available (464 aa)
LOC743115Nucleophosmin pseudogene. (255 aa)
NOP2NOP2 nucleolar protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (845 aa)
NPM1NPM1 isoform 1. (294 aa)
EGFRReceptor protein-tyrosine kinase. (1210 aa)
ERBB2Receptor protein-tyrosine kinase. (1255 aa)
ENSPTRP00000069907annotation not available (243 aa)
ENSPTRP00000074371annotation not available (264 aa)
ENSPTRP00000074499annotation not available (552 aa)
LOC737257Nucleophosmin pseudogene. (312 aa)
CREBBPCREB binding protein. (2442 aa)
MYCMyc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. Binds to the VEGFA promoter, promoting VEGFA production and subsequent sprouting angiogenesis. Regulator of somatic reprogramming, controls self-renewal of embryonic stem cells. Functions with TAF6L to activate target gene expression through RNA polymerase II pause release (By similarity). (454 aa)
KDM5BKDM5B isoform 2. (1580 aa)
ENSPTRP00000075745annotation not available (296 aa)
TFAP2BTranscription factor AP-2 beta. (467 aa)
TGFATGFA isoform 6. (193 aa)
CITED2Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2. (278 aa)
LOC46703760 kDa heat shock protein, mitochondrial pseudogene. (481 aa)
SUMO1-2Small ubiquitin-related modifier. (82 aa)
ENSPTRP00000085085annotation not available (84 aa)
ENSPTRP00000085517annotation not available (294 aa)
SUMO1-3Small ubiquitin-related modifier. (98 aa)
ENSPTRP00000085903annotation not available (98 aa)
ENSPTRP00000087196annotation not available (261 aa)
TFAP2ATranscription factor AP-2 alpha. (439 aa)
ENSPTRP00000088520annotation not available (242 aa)
CGAGlycoprotein hormones alpha chain; Belongs to the glycoprotein hormones subunit alpha family. (147 aa)
SUMO1SUMO1 isoform 3. (146 aa)
CK820_G0006425TFAP2C isoform 2. (436 aa)
LOC107973292Choriogonadotropin subunit beta 7. (113 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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