STRINGSTRING
LAMC2 LAMC2 LAMA4 LAMA4 LAMA5 LAMA5 LAMC3 LAMC3 COL11A1 COL11A1 LAMA1 LAMA1 FNDC3B FNDC3B FNDC3A FNDC3A PTK2 PTK2 MET MET ITGA2 ITGA2 SRC SRC COL5A1 COL5A1 HGF HGF ITGB1 ITGB1 LAMB1 LAMB1 COL11A2 COL11A2 LAMC1 LAMC1 COL24A1 COL24A1 MEGF11 MEGF11 COL5A2 COL5A2 FN1 FN1 COL2A1 COL2A1 LAMB3 LAMB3 COL27A1 COL27A1 COL1A2 COL1A2 LAMA2 LAMA2 LAMB2 LAMB2 COL3A1 COL3A1 COL5A3 COL5A3 LAMA3 LAMA3 COL1A1 COL1A1 ITGA3 ITGA3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LAMC2LAMC2 isoform 1. (1193 aa)
LAMA4LAMA4 isoform 3. (1823 aa)
LAMA5Laminin, alpha 5. (2203 aa)
LAMC3Laminin subunit gamma 3. (1580 aa)
COL11A1Collagen type XI alpha 1 chain. (1818 aa)
LAMA1Laminin subunit alpha 1. (3104 aa)
FNDC3BFibronectin type III domain containing 3B. (1204 aa)
FNDC3AFibronectin type III domain containing 3A. (1198 aa)
PTK2Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1113 aa)
METHepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...] (1413 aa)
ITGA2Integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor); Belongs to the integrin alpha chain family. (1183 aa)
SRCTyrosine-protein kinase. (542 aa)
COL5A1Collagen type V alpha 1 chain. (1841 aa)
HGFHepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. (812 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (801 aa)
LAMB1LAMB1 isoform 5. (1789 aa)
COL11A2COL11A2 isoform 2. (1736 aa)
LAMC1Laminin subunit gamma 1. (1609 aa)
COL24A1Collagen type XXIV alpha 1 chain. (1714 aa)
MEGF11Multiple EGF like domains 11. (1140 aa)
COL5A2Collagen type V alpha 2 chain. (1499 aa)
FN1FN1 isoform 1. (2477 aa)
COL2A1Collagen type II alpha 1 chain. (1487 aa)
LAMB3Laminin subunit beta 3. (1171 aa)
COL27A1COL27A1 isoform 1. (1860 aa)
COL1A2Collagen type I alpha 2 chain. (1366 aa)
LAMA2Laminin subunit alpha 2. (3122 aa)
LAMB2Laminin, beta 2 (Laminin S). (1798 aa)
COL3A1Collagen type III alpha 1 chain. (1466 aa)
COL5A3Collagen type V alpha 3 chain. (1745 aa)
LAMA3Laminin subunit alpha 3. (3333 aa)
COL1A1Collagen type I alpha 1 chain. (1464 aa)
ITGA3ITGA3 isoform 6; Belongs to the integrin alpha chain family. (1066 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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