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PSMC6 | Proteasome (Prosome, macropain) 26S subunit, ATPase, 6; Belongs to the AAA ATPase family. (411 aa) | ||||
PSMD3 | Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 3. (534 aa) | ||||
KAT2A | Histone acetyltransferase KAT2A isoform X1. (837 aa) | ||||
SMAD4 | Mothers against decapentaplegic homolog. (552 aa) | ||||
PSMD8 | Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 8. (350 aa) | ||||
TGFB1 | Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa) | ||||
RPS27A | RPS27A isoform 1. (156 aa) | ||||
TCF7L1 | Transcription factor 7 like 1. (587 aa) | ||||
PSMD14 | Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 14. (310 aa) | ||||
ITGA4 | Integrin, alpha 4 (Antigen CD49D, alpha 4 subunit of VLA-4 receptor); Belongs to the integrin alpha chain family. (1032 aa) | ||||
PSMD1 | 26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (953 aa) | ||||
PSMF1 | Proteasome (Prosome, macropain) inhibitor subunit 1 (PI31). (271 aa) | ||||
JAG1 | Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1218 aa) | ||||
RBPJL | Recombination signal binding protein for immunoglobulin kappa J region like. (517 aa) | ||||
PSMA7 | Proteasome subunit alpha type. (248 aa) | ||||
EP300 | E1A binding protein p300. (2175 aa) | ||||
KAT2B | Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (832 aa) | ||||
PSMD6 | Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 6. (441 aa) | ||||
PSMD2 | 26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (908 aa) | ||||
PSMB8 | Proteasome subunit beta. (276 aa) | ||||
PSMB9 | Proteasome subunit beta. (218 aa) | ||||
PSMB1 | Proteasome subunit beta. (241 aa) | ||||
PSMC2 | Proteasome (Prosome, macropain) 26S subunit, ATPase, 2; Belongs to the AAA ATPase family. (433 aa) | ||||
PSMB7 | Proteasome subunit beta. (277 aa) | ||||
NOTCH1 | NOTCH1 isoform 1. (2555 aa) | ||||
ZFHX4 | Zinc finger homeobox 4. (3615 aa) | ||||
PSMD10 | Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 10. (226 aa) | ||||
CTNNB1 | Catenin (Cadherin-associated protein), beta 1, 88kDa. (781 aa) | ||||
WWTR1 | WW domain containing transcription regulator 1. (400 aa) | ||||
PSMB10 | Proteasome subunit beta type-10. (273 aa) | ||||
HES4 | Hes family bHLH transcription factor 4. (221 aa) | ||||
SMURF1 | E3 ubiquitin-protein ligase. (757 aa) | ||||
PSMA2 | Proteasome subunit alpha type. (234 aa) | ||||
FOXO3 | FOXO3 isoform 1. (673 aa) | ||||
UBC | Polyubiquitin-C; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair [...] (693 aa) | ||||
ITGAL | ITGAL isoform 4. (344 aa) | ||||
ZFHX2 | ZFHX2 isoform 1. (2572 aa) | ||||
ENSPTRP00000054503 | annotation not available (205 aa) | ||||
PSME3 | Proteasome activator subunit 3. (265 aa) | ||||
CCND1 | CCND1 isoform 1; Belongs to the cyclin family. (295 aa) | ||||
ENSPTRP00000086535 | annotation not available (351 aa) | ||||
LOC101059795 | 26S proteasome non-ATPase regulatory subunit 2 pseudogene. (829 aa) | ||||
PSMC4 | Proteasome (Prosome, macropain) 26S subunit, ATPase, 4; Belongs to the AAA ATPase family. (421 aa) | ||||
ENSPTRP00000087746 | annotation not available (429 aa) | ||||
SMURF2 | E3 ubiquitin-protein ligase. (744 aa) | ||||
PSMB5 | Proteasome subunit beta. (263 aa) | ||||
BRD2 | Bromodomain containing 2. (835 aa) | ||||
PSMD11 | Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 11. (422 aa) | ||||
CCN2 | CTGF isoform 1. (349 aa) | ||||
ENSPTRP00000090249 | annotation not available (96 aa) | ||||
SMAD3 | Mothers against decapentaplegic homolog. (442 aa) | ||||
PSME1 | Proteasome (Prosome, macropain) activator subunit 1 (PA28 alpha). (250 aa) | ||||
PSMD9 | Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 9. (223 aa) | ||||
TEAD4 | Transcriptional enhancer factor TEF-3; Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. (434 aa) | ||||
YAP1 | Yes-associated protein 1. (508 aa) | ||||
MAML2 | Mastermind like transcriptional coactivator 2. (1150 aa) | ||||
BCL2L11 | Bcl-2-like protein 11; Induces apoptosis and anoikis. Belongs to the Bcl-2 family. (198 aa) | ||||
NINJ2 | NINJ2 isoform 1. (188 aa) | ||||
MYC | Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. Binds to the VEGFA promoter, promoting VEGFA production and subsequent sprouting angiogenesis. Regulator of somatic reprogramming, controls self-renewal of embryonic stem cells. Functions with TAF6L to activate target gene expression through RNA polymerase II pause release (By similarity). (454 aa) | ||||
CREBBP | CREB binding protein. (2442 aa) | ||||
ENSPTRP00000074972 | annotation not available (252 aa) | ||||
CK820_G0042370 | TEAD2 isoform 6. (427 aa) | ||||
ENSPTRP00000073673 | annotation not available (196 aa) | ||||
HDAC4 | Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1089 aa) | ||||
PSMD13 | Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 13. (399 aa) | ||||
LOC470312 | 26S proteasome regulatory subunit 4 pseudogene. (374 aa) | ||||
ENSPTRP00000071568 | annotation not available (98 aa) | ||||
PSMB3 | Proteasome subunit beta. (205 aa) | ||||
ENSPTRP00000069172 | annotation not available (353 aa) | ||||
PSMB6 | Proteasome subunit beta. (244 aa) | ||||
ENSPTRP00000067920 | annotation not available (392 aa) | ||||
ENSPTRP00000067263 | Ubiquitin-large subunit ribosomal protein L40e. (119 aa) | ||||
MAMLD1 | MAMLD1 isoform 3. (984 aa) | ||||
ENSPTRP00000065241 | annotation not available (350 aa) | ||||
SNW1 | SNW domain containing 1. (571 aa) | ||||
ERAS | ES cell expressed Ras. (233 aa) | ||||
ENSPTRP00000064540 | annotation not available (358 aa) | ||||
HES1 | Hes family bHLH transcription factor 1. (280 aa) | ||||
PSME3-2 | Proteasome activator subunit 3. (265 aa) | ||||
PSMD5 | PSMD5 isoform 1. (509 aa) | ||||
ENSPTRP00000062484 | annotation not available (224 aa) | ||||
PSMC3 | Proteasome (Prosome, macropain) 26S subunit, ATPase, 3; Belongs to the AAA ATPase family. (446 aa) | ||||
PSMA1 | Proteasome subunit alpha type. (269 aa) | ||||
PSMB4 | Proteasome subunit beta; Belongs to the peptidase T1B family. (264 aa) | ||||
PSMB2 | Proteasome subunit beta. (201 aa) | ||||
RUNX3 | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (428 aa) | ||||
PSME2 | Proteasome (Prosome, macropain) activator subunit 2 (PA28 beta). (239 aa) | ||||
ENSPTRP00000060412 | annotation not available (156 aa) | ||||
CBFB | Core-binding factor, beta subunit. (182 aa) | ||||
ENSPTRP00000060300 | annotation not available (221 aa) | ||||
CDKN1A | Cyclin-dependent kinase inhibitor 1A (P21, Cip1). (276 aa) | ||||
KXD1 | UBA52 isoform 10. (231 aa) | ||||
MAML1 | MAML1 isoform 1. (1016 aa) | ||||
PSMC5 | Proteasome (Prosome, macropain) 26S subunit, ATPase, 5; Belongs to the AAA ATPase family. (406 aa) | ||||
ENSPTRP00000085348 | annotation not available (302 aa) | ||||
FNDC3B | Fibronectin type III domain containing 3B. (1204 aa) | ||||
KRAS | V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog. (189 aa) | ||||
ENSPTRP00000084513 | annotation not available (205 aa) | ||||
FNDC3A | Fibronectin type III domain containing 3A. (1198 aa) | ||||
TEAD1 | TEAD1 isoform 6. (445 aa) | ||||
TEAD2 | TEA domain transcription factor 2. (451 aa) | ||||
RORC | RAR related orphan receptor C. (525 aa) | ||||
ENSPTRP00000082443 | annotation not available (351 aa) | ||||
ENSPTRP00000082196 | annotation not available (376 aa) | ||||
TEAD3 | TEA domain transcription factor 3. (435 aa) | ||||
ENSPTRP00000081714 | annotation not available (310 aa) | ||||
MAMLD1-2 | Mastermind-like domain containing 1. (722 aa) | ||||
TCF7L2 | Transcription factor 7 like 2. (619 aa) | ||||
TCF7 | Transcription factor 7. (481 aa) | ||||
CK820_G0002453 | PSMC6 isoform 12. (340 aa) | ||||
LEF1 | Lymphoid enhancer binding factor 1. (414 aa) | ||||
PSMA5 | Proteasome subunit alpha type. (241 aa) | ||||
MAML3 | MAML3 isoform 1. (1134 aa) | ||||
PSMD12 | Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 12. (480 aa) | ||||
RBPJ | Recombination signal binding protein for immunoglobulin kappa J region. (500 aa) | ||||
LOC461963 | PSME2 isoform 10. (224 aa) | ||||
ENSPTRP00000077985 | annotation not available (153 aa) | ||||
SRC | Tyrosine-protein kinase. (542 aa) | ||||
ENSPTRP00000076582 | annotation not available (377 aa) | ||||
RUNX1 | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (480 aa) | ||||
SPP1 | Secreted phosphoprotein 1. (314 aa) | ||||
ENSPTRP00000091341 | annotation not available (379 aa) | ||||
PSMD4 | PSMD4 isoform 2. (382 aa) | ||||
PSMA6 | Proteasome subunit alpha type. (246 aa) | ||||
PSMA3 | Proteasome subunit alpha type. (255 aa) | ||||
PSMC1 | Proteasome (Prosome, macropain) 26S subunit, ATPase, 1; Belongs to the AAA ATPase family. (440 aa) | ||||
PSMA4 | Proteasome subunit alpha type-4 isoform X2. (261 aa) | ||||
ZFHX3 | Zinc finger homeobox 3. (3688 aa) | ||||
PSMD7 | Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 7. (324 aa) | ||||
TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (393 aa) |