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| | PSMB2 | Proteasome subunit beta. (201 aa) |
| | PSMB4 | Proteasome subunit beta; Belongs to the peptidase T1B family. (264 aa) |
| | BGLAP | Osteocalcin; Constitutes 1-2% of the total bone protein. It binds strongly to apatite and calcium. (100 aa) |
| | UCMA | UCMA isoform 1. (138 aa) |
| | PSMA1 | Proteasome subunit alpha type. (269 aa) |
| | PSMC3 | Proteasome (Prosome, macropain) 26S subunit, ATPase, 3; Belongs to the AAA ATPase family. (446 aa) |
| | ESRRA | Estrogen-related receptor alpha. (422 aa) |
| | RBM4 | RNA-binding protein 14. (669 aa) |
| | YAP1 | Yes-associated protein 1. (508 aa) |
| | ITGA5 | ITGA5 isoform 2; Belongs to the integrin alpha chain family. (1098 aa) |
| | PSMD9 | Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 9. (223 aa) |
| | RB1 | RB transcriptional corepressor 1. (928 aa) |
| | PSME1 | Proteasome (Prosome, macropain) activator subunit 1 (PA28 alpha). (250 aa) |
| | PSME2 | Proteasome (Prosome, macropain) activator subunit 2 (PA28 beta). (239 aa) |
| | PSMA6 | Proteasome subunit alpha type. (246 aa) |
| | LGALS3 | Galectin. (250 aa) |
| | PSMA3 | Proteasome subunit alpha type. (255 aa) |
| | PSMC1 | Proteasome (Prosome, macropain) 26S subunit, ATPase, 1; Belongs to the AAA ATPase family. (440 aa) |
| | SMAD6 | Mothers against decapentaplegic homolog. (496 aa) |
| | PSMA4 | Proteasome subunit alpha type-4 isoform X2. (261 aa) |
| | STUB1 | STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase. (303 aa) |
| | SOX8 | SOX8 isoform 1. (446 aa) |
| | ZNF423 | Zinc finger protein 423. (1284 aa) |
| | PSMD7 | Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 7. (324 aa) |
| | PSMD11 | Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 11. (422 aa) |
| | PSMD3 | Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 3. (534 aa) |
| | COL1A1 | Collagen type I alpha 1 chain. (1464 aa) |
| | SOX9 | Transcription factor SOX-9; Transcriptional regulator that plays a role in chondrocytes differentiation and skeletal development. Binds to the COL2A1 promoter and activates COL2A1 expression, as part of a complex with ZNF219. (509 aa) |
| | PSMA8 | Proteasome subunit alpha type. (256 aa) |
| | SMAD4 | Mothers against decapentaplegic homolog. (552 aa) |
| | PSMD8 | Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 8. (350 aa) |
| | RPS27A | RPS27A isoform 1. (156 aa) |
| | PSMD14 | Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 14. (310 aa) |
| | IHH | Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (411 aa) |
| | PSMD1 | 26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (953 aa) |
| | PSMF1 | Proteasome (Prosome, macropain) inhibitor subunit 1 (PI31). (271 aa) |
| | BMP2 | Bone morphogenetic protein 2. (398 aa) |
| | ZNF831 | Zinc finger protein 831. (1679 aa) |
| | PSMA7 | Proteasome subunit alpha type. (248 aa) |
| | MAPK1 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa) |
| | RBX1 | Ring-box 1, E3 ubiquitin protein ligase. (108 aa) |
| | PSMD6 | Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 6. (441 aa) |
| | PSMD2 | 26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (908 aa) |
| | PPARGC1A | PPARG coactivator 1 alpha. (809 aa) |
| | SMAD1 | Mothers against decapentaplegic homolog. (469 aa) |
| | FBXW7 | F-box and WD repeat domain containing 7. (707 aa) |
| | SKP2 | S-phase kinase-associated protein 2 (P45). (425 aa) |
| | CCNB1 | CCNB1 isoform 1; Belongs to the cyclin family. (433 aa) |
| | HDAC3 | Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (428 aa) |
| | NR3C1 | NR3C1 isoform 5. (778 aa) |
| | MSX2 | Homeobox protein MSX-2; Acts as a transcriptional regulator in bone development. Represses the ALPL promoter activity and antagonizes the stimulatory effect of DLX5 on ALPL expression during osteoblast differentiation. Probable morphogenetic role. May play a role in limb-pattern formation. In osteoblasts, suppresses transcription driven by the osteocalcin FGF response element (OCFRE). Binds to the homeodomain-response element of the ALPL promoter (By similarity); Belongs to the Msh homeobox family. (267 aa) |
| | PSMB8 | Proteasome subunit beta. (276 aa) |
| | PSMB9 | Proteasome subunit beta. (218 aa) |
| | HEY2 | Hairy/enhancer-of-split related with YRPW motif 2. (337 aa) |
| | ESR1 | Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (595 aa) |
| | PSMB1 | Proteasome subunit beta. (241 aa) |
| | GLI3 | Transcriptional repressor GLI3R; Has a dual function as a transcriptional activator and a repressor of the sonic hedgehog (Shh) pathway, and plays a role in limb development. The full-length GLI3 form (GLI3FL) after phosphorylation and nuclear translocation, acts as an activator (GLI3A) while GLI3R, its C-terminally truncated form, acts as a repressor. A proper balance between the GLI3 activator and the repressor GLI3R, rather than the repressor gradient itself or the activator/repressor ratio gradient, specifies limb digit number and identity. In concert with TRPS1, plays a role in re [...] (1580 aa) |
| | DLX5 | Distal-less homeobox 5. (289 aa) |
| | PSMC2 | Proteasome (Prosome, macropain) 26S subunit, ATPase, 2; Belongs to the AAA ATPase family. (433 aa) |
| | CUL1 | CUL1 isoform 1; Belongs to the cullin family. (776 aa) |
| | WWP1 | E3 ubiquitin-protein ligase. (922 aa) |
| | PSMB7 | Proteasome subunit beta. (277 aa) |
| | HDAC6 | Histone deacetylase 6. (146 aa) |
| | CDK4 | Cyclin-dependent kinase 4; Belongs to the protein kinase superfamily. (303 aa) |
| | GLI2 | GLI family zinc finger 2. (1587 aa) |
| | PSMD10 | Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 10. (226 aa) |
| | WWTR1 | WW domain containing transcription regulator 1. (400 aa) |
| | HIVEP2 | HIVEP2 isoform 2. (2446 aa) |
| | PSMB10 | Proteasome subunit beta type-10. (273 aa) |
| | HES4 | Hes family bHLH transcription factor 4. (221 aa) |
| | ITGBL1 | Integrin, beta-like 1 (With EGF-like repeat domains). (494 aa) |
| | SMURF1 | E3 ubiquitin-protein ligase. (757 aa) |
| | PSMA2 | Proteasome subunit alpha type. (234 aa) |
| | TWIST1 | TWIST1 isoform 2. (163 aa) |
| | CDK1 | Cyclin-dependent kinase 1; Belongs to the protein kinase superfamily. (297 aa) |
| | HAND2 | Heart and neural crest derivatives expressed 2. (217 aa) |
| | UBC | Polyubiquitin-C; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair [...] (693 aa) |
| | MAPK3 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa) |
| | ENSPTRP00000054503 | annotation not available (205 aa) |
| | SP8 | Sp8 transcription factor. (507 aa) |
| | PSMC5 | Proteasome (Prosome, macropain) 26S subunit, ATPase, 5; Belongs to the AAA ATPase family. (406 aa) |
| | ZNF521 | Zinc finger protein 521. (1311 aa) |
| | DLX6 | DLX6 isoform 1. (295 aa) |
| | KXD1 | UBA52 isoform 10. (231 aa) |
| | CDKN1A | Cyclin-dependent kinase inhibitor 1A (P21, Cip1). (276 aa) |
| | ENSPTRP00000060300 | annotation not available (221 aa) |
| | CBFB | Core-binding factor, beta subunit. (182 aa) |
| | ENSPTRP00000060412 | annotation not available (156 aa) |
| | CK820_G0012168 | ABL1 isoform 3. (1149 aa) |
| | ENSPTRP00000062265 | annotation not available (82 aa) |
| | ENSPTRP00000062484 | annotation not available (224 aa) |
| | PSMD5 | PSMD5 isoform 1. (509 aa) |
| | PSME3-2 | Proteasome activator subunit 3. (265 aa) |
| | HES1 | Hes family bHLH transcription factor 1. (280 aa) |
| | ENSPTRP00000064540 | annotation not available (358 aa) |
| | ENSPTRP00000064916 | annotation not available (631 aa) |
| | ENSPTRP00000065241 | annotation not available (350 aa) |
| | RUNX2 | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (569 aa) |
| | ENSPTRP00000067263 | Ubiquitin-large subunit ribosomal protein L40e. (119 aa) |
| | ENSPTRP00000067920 | annotation not available (392 aa) |
| | PSMB6 | Proteasome subunit beta. (244 aa) |
| | NKX3-2 | NKX3-2 isoform 1. (333 aa) |
| | HEY1 | Hes related family bHLH transcription factor with YRPW motif 1. (304 aa) |
| | ENSPTRP00000069172 | annotation not available (353 aa) |
| | PSMB3 | Proteasome subunit beta. (205 aa) |
| | SKP1 | T0093123 isoform 1; Belongs to the SKP1 family. (163 aa) |
| | ENSPTRP00000071568 | annotation not available (98 aa) |
| | LOC470312 | 26S proteasome regulatory subunit 4 pseudogene. (374 aa) |
| | PSMD13 | Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 13. (399 aa) |
| | ENSPTRP00000071907 | annotation not available (164 aa) |
| | LOC748658 | LOW QUALITY PROTEIN: homeobox protein MSX-2-like. (312 aa) |
| | ABL1 | Tyrosine-protein kinase. (1149 aa) |
| | HDAC4 | Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1089 aa) |
| | ENSPTRP00000073673 | annotation not available (196 aa) |
| | ENSPTRP00000074972 | annotation not available (252 aa) |
| | SOX30 | SOX30 isoform 2. (753 aa) |
| | MAF | MAF isoform 2; Belongs to the bZIP family. (402 aa) |
| | MMP13 | Matrix metallopeptidase 13. (498 aa) |
| | ENSPTRP00000076582 | annotation not available (377 aa) |
| | HIVEP1 | HIVEP1 isoform 1. (2718 aa) |
| | SRC | Tyrosine-protein kinase. (542 aa) |
| | AR | Androgen receptor; Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcription factor activity is modulated by bound coactivator and corepressor proteins like ZBTB7A that recruits NCOR1 and NCOR2 to the androgen response elements/ARE on target genes, negatively regulating androgen receptor signaling and androgen-induced cell proliferation. Transcription activation is also down-regulated by NR0B2. Activated, but not phosphorylated, by HIPK3 and ZIPK/DAPK3. (912 aa) |
| | ENSPTRP00000077036 | annotation not available (396 aa) |
| | PPARGC1B | PPARGC1B isoform 2. (1023 aa) |
| | ENSPTRP00000077985 | annotation not available (153 aa) |
| | SP7 | Sp7 transcription factor. (431 aa) |
| | LOC461963 | PSME2 isoform 10. (224 aa) |
| | LOC100612565 | Steroid hormone receptor ERR1 pseudogene. (396 aa) |
| | LOC471113 | NEDD4-like E3 ubiquitin-protein ligase WWP1 pseudogene. (783 aa) |
| | PSMD12 | Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 12. (480 aa) |
| | SP9 | Sp9 transcription factor. (481 aa) |
| | PSMA5 | Proteasome subunit alpha type. (241 aa) |
| | SATB2 | DNA-binding protein SATB. (733 aa) |
| | CK820_G0002453 | PSMC6 isoform 12. (340 aa) |
| | ENSPTRP00000081537 | annotation not available (449 aa) |
| | GSK3B | Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (481 aa) |
| | ENSPTRP00000082443 | annotation not available (351 aa) |
| | PSME4 | Proteasome (Prosome, macropain) activator subunit 4. (1844 aa) |
| | AKT1 | AKT1 isoform 3; Belongs to the protein kinase superfamily. (480 aa) |
| | ENSPTRP00000084513 | annotation not available (205 aa) |
| | ENSPTRP00000085348 | annotation not available (302 aa) |
| | PSME3 | Proteasome activator subunit 3. (265 aa) |
| | AKT3 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa) |
| | CCND1 | CCND1 isoform 1; Belongs to the cyclin family. (295 aa) |
| | CUL1-2 | Cullin 1. (776 aa) |
| | ENSPTRP00000086535 | annotation not available (351 aa) |
| | LOC101059795 | 26S proteasome non-ATPase regulatory subunit 2 pseudogene. (829 aa) |
| | PSMC4 | Proteasome (Prosome, macropain) 26S subunit, ATPase, 4; Belongs to the AAA ATPase family. (421 aa) |
| | PSMB5 | Proteasome subunit beta. (263 aa) |
| | AKT2 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa) |
| | PSMC6 | Proteasome (Prosome, macropain) 26S subunit, ATPase, 6; Belongs to the AAA ATPase family. (411 aa) |
| | ENSPTRP00000090249 | annotation not available (96 aa) |
| | YES1 | Tyrosine-protein kinase. (558 aa) |
| | STAT1 | Signal transducer and activator of transcription. (758 aa) |
| | PSMD4 | PSMD4 isoform 2. (382 aa) |
| | ENSPTRP00000091341 | annotation not available (379 aa) |
| | PPM1D | Protein phosphatase, Mg2+/Mn2+ dependent, 1D. (605 aa) |
| | RUNX1 | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (480 aa) |
| | HIVEP3 | Human immunodeficiency virus type I enhancer binding protein 3. (2405 aa) |
