(19 nodes) HDL assembly network (Pan troglodytes)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PTCHD3	Patched domain containing 3. (769 aa)
	PTCHD1	Patched domain containing 1. (888 aa)
	ZDHHC8	Probable palmitoyltransferase ZDHHC8; Putative palmitoyltransferase involved in glutamatergic transmission; Belongs to the DHHC palmitoyltransferase family. ERF2/ZDHHC9 subfamily. (765 aa)
	ENSPTRP00000080550	Apolipoprotein A-I Proapolipoprotein A-I Truncated apolipoprotein A-I. (267 aa)
	ENSPTRP00000079643	annotation not available (95 aa)
	PZP	PZP alpha-2-macroglobulin like. (1482 aa)
	LOC465369	LOW QUALITY PROTEIN: ovostatin homolog 1. (153 aa)
	ABCA1	ATP-binding cassette, sub-family A (ABC1), member 1. (2264 aa)
	ZDHHC19	Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (309 aa)
	A2M	Alpha-2-macroglobulin. (1474 aa)
	A2ML1	A2ML1 isoform 1. (1454 aa)
	PRKACB	Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (398 aa)
	PRKACG	Protein kinase cAMP-activated catalytic subunit gamma; Belongs to the protein kinase superfamily. (351 aa)
	BMP1	Metalloendopeptidase. (986 aa)
	SMPDL3A	Acid sphingomyelinase-like phosphodiesterase. (453 aa)
	PTCHD4	Patched domain containing 4. (846 aa)
	PRKACA	PRKACA isoform 7; Belongs to the protein kinase superfamily. (289 aa)
	PLEKHD1	Pleckstrin homology and coiled-coil domain containing D1. (506 aa)
	APOA1	Truncated apolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility (By similarity). (267 aa)

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABCA1	APOA1	ENSPTRP00000062700	ENSPTRP00000007404	ATP-binding cassette, sub-family A (ABC1), member 1.	Truncated apolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility (By similarity).	0.943
ABCA1	ENSPTRP00000080550	ENSPTRP00000062700	ENSPTRP00000080550	ATP-binding cassette, sub-family A (ABC1), member 1.	Apolipoprotein A-I Proapolipoprotein A-I Truncated apolipoprotein A-I.	0.465
ABCA1	PRKACA	ENSPTRP00000062700	ENSPTRP00000018062	ATP-binding cassette, sub-family A (ABC1), member 1.	PRKACA isoform 7; Belongs to the protein kinase superfamily.	0.470
ABCA1	PRKACB	ENSPTRP00000062700	ENSPTRP00000042330	ATP-binding cassette, sub-family A (ABC1), member 1.	Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily.	0.472
ABCA1	PRKACG	ENSPTRP00000062700	ENSPTRP00000035898	ATP-binding cassette, sub-family A (ABC1), member 1.	Protein kinase cAMP-activated catalytic subunit gamma; Belongs to the protein kinase superfamily.	0.470
ABCA1	ZDHHC8	ENSPTRP00000062700	ENSPTRP00000086070	ATP-binding cassette, sub-family A (ABC1), member 1.	Probable palmitoyltransferase ZDHHC8; Putative palmitoyltransferase involved in glutamatergic transmission; Belongs to the DHHC palmitoyltransferase family. ERF2/ZDHHC9 subfamily.	0.624
APOA1	ABCA1	ENSPTRP00000007404	ENSPTRP00000062700	Truncated apolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility (By similarity).	ATP-binding cassette, sub-family A (ABC1), member 1.	0.943
APOA1	ENSPTRP00000080550	ENSPTRP00000007404	ENSPTRP00000080550	Truncated apolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility (By similarity).	Apolipoprotein A-I Proapolipoprotein A-I Truncated apolipoprotein A-I.	0.545
ENSPTRP00000080550	ABCA1	ENSPTRP00000080550	ENSPTRP00000062700	Apolipoprotein A-I Proapolipoprotein A-I Truncated apolipoprotein A-I.	ATP-binding cassette, sub-family A (ABC1), member 1.	0.465
ENSPTRP00000080550	APOA1	ENSPTRP00000080550	ENSPTRP00000007404	Apolipoprotein A-I Proapolipoprotein A-I Truncated apolipoprotein A-I.	Truncated apolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility (By similarity).	0.545
PRKACA	ABCA1	ENSPTRP00000018062	ENSPTRP00000062700	PRKACA isoform 7; Belongs to the protein kinase superfamily.	ATP-binding cassette, sub-family A (ABC1), member 1.	0.470
PRKACA	PRKACB	ENSPTRP00000018062	ENSPTRP00000042330	PRKACA isoform 7; Belongs to the protein kinase superfamily.	Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily.	0.984
PRKACA	PRKACG	ENSPTRP00000018062	ENSPTRP00000035898	PRKACA isoform 7; Belongs to the protein kinase superfamily.	Protein kinase cAMP-activated catalytic subunit gamma; Belongs to the protein kinase superfamily.	0.956
PRKACB	ABCA1	ENSPTRP00000042330	ENSPTRP00000062700	Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily.	ATP-binding cassette, sub-family A (ABC1), member 1.	0.472
PRKACB	PRKACA	ENSPTRP00000042330	ENSPTRP00000018062	Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily.	PRKACA isoform 7; Belongs to the protein kinase superfamily.	0.984
PRKACB	PRKACG	ENSPTRP00000042330	ENSPTRP00000035898	Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily.	Protein kinase cAMP-activated catalytic subunit gamma; Belongs to the protein kinase superfamily.	0.959
PRKACG	ABCA1	ENSPTRP00000035898	ENSPTRP00000062700	Protein kinase cAMP-activated catalytic subunit gamma; Belongs to the protein kinase superfamily.	ATP-binding cassette, sub-family A (ABC1), member 1.	0.470
PRKACG	PRKACA	ENSPTRP00000035898	ENSPTRP00000018062	Protein kinase cAMP-activated catalytic subunit gamma; Belongs to the protein kinase superfamily.	PRKACA isoform 7; Belongs to the protein kinase superfamily.	0.956
PRKACG	PRKACB	ENSPTRP00000035898	ENSPTRP00000042330	Protein kinase cAMP-activated catalytic subunit gamma; Belongs to the protein kinase superfamily.	Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily.	0.959
ZDHHC8	ABCA1	ENSPTRP00000086070	ENSPTRP00000062700	Probable palmitoyltransferase ZDHHC8; Putative palmitoyltransferase involved in glutamatergic transmission; Belongs to the DHHC palmitoyltransferase family. ERF2/ZDHHC9 subfamily.	ATP-binding cassette, sub-family A (ABC1), member 1.	0.624