STRINGSTRING
PIK3CB PIK3CB HCK HCK RPS27A RPS27A PIK3R2 PIK3R2 VAV1 VAV1 GRB2 GRB2 CBL CBL PIK3CD PIK3CD YES1 YES1 ENSPTRP00000089450 ENSPTRP00000089450 PIK3CA PIK3CA CRK CRK ENSPTRP00000081537 ENSPTRP00000081537 FYN FYN PIK3R1 PIK3R1 SYK SYK RAPGEF1 RAPGEF1 ENSPTRP00000071568 ENSPTRP00000071568 ENSPTRP00000067263 ENSPTRP00000067263 PIK3R3 PIK3R3 ENSPTRP00000060412 ENSPTRP00000060412 KXD1 KXD1 UBC UBC CRKL CRKL LYN LYN
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1084 aa)
HCKTyrosine-protein kinase. (526 aa)
RPS27ARPS27A isoform 1. (156 aa)
PIK3R2Phosphoinositide-3-kinase, regulatory subunit 2 (Beta). (728 aa)
VAV1Vav guanine nucleotide exchange factor 1. (845 aa)
GRB2Growth factor receptor-bound protein 2. (217 aa)
CBLCas-Br-M (Murine) ecotropic retroviral transforming sequence. (906 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
YES1Tyrosine-protein kinase. (558 aa)
ENSPTRP00000089450annotation not available (303 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1034 aa)
CRKV-crk sarcoma virus CT10 oncogene homolog (Avian). (304 aa)
ENSPTRP00000081537annotation not available (449 aa)
FYNTyrosine-protein kinase. (537 aa)
PIK3R1Phosphoinositide-3-kinase, regulatory subunit 1 (Alpha). (724 aa)
SYKTyrosine-protein kinase. (635 aa)
RAPGEF1RAPGEF1 isoform 5. (1065 aa)
ENSPTRP00000071568annotation not available (98 aa)
ENSPTRP00000067263Ubiquitin-large subunit ribosomal protein L40e. (119 aa)
PIK3R3Phosphoinositide-3-kinase, regulatory subunit 3 (Gamma). (478 aa)
ENSPTRP00000060412annotation not available (156 aa)
KXD1UBA52 isoform 10. (231 aa)
UBCPolyubiquitin-C; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair [...] (693 aa)
CRKLV-crk sarcoma virus CT10 oncogene homolog (Avian)-like. (303 aa)
LYNTyrosine-protein kinase. (512 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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