STRINGSTRING
SKP1 SKP1 ATP6V1F ATP6V1F ENSPTRP00000070343 ENSPTRP00000070343 LCN2 LCN2 CYB561 CYB561 ENSPTRP00000071568 ENSPTRP00000071568 SLC11A2 SLC11A2 ENSPTRP00000071907 ENSPTRP00000071907 MPPE1 MPPE1 LOC745048 LOC745048 ATP6AP1L ATP6AP1L LOC100613627 LOC100613627 CELF3 CELF3 ATP6V1D ATP6V1D SLC46A3 SLC46A3 ATP6V0A2 ATP6V0A2 CAND1 CAND1 HEPHL1 HEPHL1 TCIRG1 TCIRG1 CNST CNST FLVCR1 FLVCR1 ATP6V1E1-2 ATP6V1E1-2 ENSPTRP00000075851 ENSPTRP00000075851 CELF6 CELF6 ATP6V1E1 ATP6V1E1 ATP6V1G3 ATP6V1G3 ENSPTRP00000077224 ENSPTRP00000077224 ATP6V1H ATP6V1H ENSPTRP00000078047 ENSPTRP00000078047 GLRX3 GLRX3 ENSPTRP00000078404 ENSPTRP00000078404 CK820_G0051636 CK820_G0051636 RRP12 RRP12 HFE HFE ATP6V0A4-2 ATP6V0A4-2 CYB561A3 CYB561A3 ENSPTRP00000080278 ENSPTRP00000080278 ENSPTRP00000080853 ENSPTRP00000080853 ATP6V0B ATP6V0B ATP6V1B2 ATP6V1B2 FLVCR2 FLVCR2 ENSPTRP00000082434 ENSPTRP00000082434 ENSPTRP00000082988 ENSPTRP00000082988 ATP6V1G2 ATP6V1G2 FTH1 FTH1 STEAP2 STEAP2 ENSPTRP00000084393 ENSPTRP00000084393 ENSPTRP00000084626 ENSPTRP00000084626 ENSPTRP00000084909 ENSPTRP00000084909 ATP6V0E2-2 ATP6V0E2-2 CUL1-2 CUL1-2 ENSPTRP00000086815 ENSPTRP00000086815 STEAP2-2 STEAP2-2 ATP6V1C2 ATP6V1C2 ATP6V0A1 ATP6V0A1 ENSPTRP00000089762 ENSPTRP00000089762 NEDD8 NEDD8 ENSPTRP00000090693 ENSPTRP00000090693 LOC101059049 LOC101059049 ENSPTRP00000091795 ENSPTRP00000091795 ENSPTRP00000092342 ENSPTRP00000092342 CELF4 CELF4 CYBRD1 CYBRD1 SLC40A1 SLC40A1 HMOX1 HMOX1 CAND2 CAND2 ATP6V1A ATP6V1A SLC49A4 SLC49A4 TF TF CP CP SLC49A3 SLC49A3 FBXL5 FBXL5 ABCG2 ABCG2 FTMT FTMT SLC22A23 SLC22A23 TFR2 TFR2 ATP6V0A4 ATP6V0A4 CUL1 CUL1 STEAP3 STEAP3 ATP6V1B1 ATP6V1B1 RPS27A RPS27A ATP6V1E2 ATP6V1E2 LIM2 LIM2 MCOLN1 MCOLN1 CELF5 CELF5 ATP6V0D1 ATP6V0D1 HMOX2 HMOX2 ATP6V0C ATP6V0C IREB2 IREB2 SLC22A17 SLC22A17 ATP6AP1 ATP6AP1 FTHL17 FTHL17 ATP6V1G1 ATP6V1G1 ACO1 ACO1 ATP6V0D2 ATP6V0D2 TFRC TFRC ATP6V0E1 ATP6V0E1 STEAP4 STEAP4 LCN2-2 LCN2-2 UBC UBC ATP6V1C1 ATP6V1C1 ATP6V1F-2 ATP6V1F-2 KXD1 KXD1 FTL FTL ENSPTRP00000060412 ENSPTRP00000060412 ENSPTRP00000060867 ENSPTRP00000060867 ATP6V0E2 ATP6V0E2 ENSPTRP00000062516 ENSPTRP00000062516 LOC101059804 LOC101059804 HEPH HEPH LOC104001552 LOC104001552 ENSPTRP00000064916 ENSPTRP00000064916 ENSPTRP00000067263 ENSPTRP00000067263 ENSPTRP00000067636 ENSPTRP00000067636 SLC46A1 SLC46A1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SKP1T0093123 isoform 1; Belongs to the SKP1 family. (163 aa)
ATP6V1FV-type proton ATPase subunit F; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (147 aa)
ENSPTRP00000070343annotation not available (173 aa)
LCN2Lipocalin 2. (240 aa)
CYB561CYB561 isoform 16. (318 aa)
ENSPTRP00000071568annotation not available (98 aa)
SLC11A2SLC11A2 isoform 1. (590 aa)
ENSPTRP00000071907annotation not available (164 aa)
MPPE1Metallophosphoesterase 1. (397 aa)
LOC745048ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1. (195 aa)
ATP6AP1LATP6AP1L isoform 3. (388 aa)
LOC100613627Ferritin heavy chain pseudogene. (165 aa)
CELF3CELF3 isoform 2. (457 aa)
ATP6V1DATPase, H+ transporting, lysosomal 34kDa, V1 subunit D. (247 aa)
SLC46A3Solute carrier family 46 member 3. (463 aa)
ATP6V0A2V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (856 aa)
CAND1Cullin-associated and neddylation-dissociated 1. (1230 aa)
HEPHL1HEPHL1 isoform 1; Belongs to the multicopper oxidase family. (1159 aa)
TCIRG1V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (830 aa)
CNSTConsortin, connexin sorting protein. (725 aa)
FLVCR1Feline leukemia virus subgroup C cellular receptor 1. (569 aa)
ATP6V1E1-2ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1. (176 aa)
ENSPTRP00000075851annotation not available (171 aa)
CELF6T0127720 isoform 1. (481 aa)
ATP6V1E1ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1. (191 aa)
ATP6V1G3V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (124 aa)
ENSPTRP00000077224annotation not available (84 aa)
ATP6V1HV-type proton ATPase subunit H; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit H activates ATPase activity of the enzyme and couples ATPase activity to proton flow. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. (483 aa)
ENSPTRP00000078047annotation not available (132 aa)
GLRX3GLRX3 isoform 1. (335 aa)
ENSPTRP00000078404annotation not available (801 aa)
CK820_G0051636SLC22A31 isoform 1. (533 aa)
RRP12Ribosomal RNA processing 12 homolog. (1302 aa)
HFEHereditary hemochromatosis protein homolog; Binds to transferrin receptor (TFR) and reduces its affinity for iron-loaded transferrin. (348 aa)
ATP6V0A4-2V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (840 aa)
CYB561A3Cytochrome b561 family member A3. (259 aa)
ENSPTRP00000080278annotation not available (136 aa)
ENSPTRP00000080853annotation not available (113 aa)
ATP6V0BATPase H+ transporting V0 subunit b; Belongs to the V-ATPase proteolipid subunit family. (261 aa)
ATP6V1B2Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family. (525 aa)
FLVCR2FLVCR2 isoform 1. (525 aa)
ENSPTRP00000082434annotation not available (288 aa)
ENSPTRP00000082988annotation not available (168 aa)
ATP6V1G2V-type proton ATPase subunit G 1; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (158 aa)
FTH1Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. (183 aa)
STEAP2Six transmembrane epithelial antigen of the prostate 2. (490 aa)
ENSPTRP00000084393annotation not available (72 aa)
ENSPTRP00000084626annotation not available (113 aa)
ENSPTRP00000084909annotation not available (278 aa)
ATP6V0E2-2ATPase H+ transporting V0 subunit e2. (213 aa)
CUL1-2Cullin 1. (776 aa)
ENSPTRP00000086815annotation not available (145 aa)
STEAP2-2STEAP2 metalloreductase. (490 aa)
ATP6V1C2V-type proton ATPase subunit C; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (437 aa)
ATP6V0A1V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (838 aa)
ENSPTRP00000089762annotation not available (77 aa)
NEDD8Ubiquitin-like protein Nedd8. (81 aa)
ENSPTRP00000090693annotation not available (46 aa)
LOC101059049Ferritin heavy chain pseudogene. (173 aa)
ENSPTRP00000091795annotation not available (159 aa)
ENSPTRP00000092342annotation not available (158 aa)
CELF4CUGBP Elav-like family member 4. (486 aa)
CYBRD1Cytochrome b reductase 1. (286 aa)
SLC40A1Solute carrier family 40 protein; May be involved in iron transport and iron homeostasis. Belongs to the ferroportin (FP) (TC 2.A.100) family. SLC40A subfamily. (571 aa)
HMOX1Heme oxygenase; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. (311 aa)
CAND2Cullin associated and neddylation dissociated 2 (putative). (1236 aa)
ATP6V1AATPase, H+ transporting, lysosomal 70kDa, V1 subunit A. (618 aa)
SLC49A4Solute carrier family 49 member 4. (478 aa)
TFSerotransferrin; Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. It is responsible for the transport of iron from sites of absorption and heme degradation to those of storage and utilization. Serum transferrin may also have a further role in stimulating cell proliferation (By similarity). (698 aa)
CPCP isoform 1; Belongs to the multicopper oxidase family. (1069 aa)
SLC49A3Major facilitator superfamily domain containing 7. (559 aa)
FBXL5F-box and leucine-rich repeat protein 5. (691 aa)
ABCG2ATP-binding cassette, sub-family G (WHITE), member 2. (655 aa)
FTMTFerritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. (242 aa)
SLC22A23Solute carrier family 22 member 23. (694 aa)
TFR2Transferrin receptor 2. (801 aa)
ATP6V0A4ATPase H+ transporting V0 subunit a4. (840 aa)
CUL1CUL1 isoform 1; Belongs to the cullin family. (776 aa)
STEAP3STEAP3 metalloreductase. (498 aa)
ATP6V1B1Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family. (513 aa)
RPS27ARPS27A isoform 1. (156 aa)
ATP6V1E2ATPase H+ transporting V1 subunit E2. (226 aa)
LIM2Lens fiber membrane intrinsic protein; Present in the thicker 16-17 nm junctions of mammalian lens fiber cells, where it may contribute to cell junctional organization. Acts as a receptor for calmodulin. May play an important role in both lens development and cataractogenesis; Belongs to the PMP-22/EMP/MP20 family. (215 aa)
MCOLN1MCOLN1 isoform 1. (601 aa)
CELF5CUGBP Elav-like family member 5. (485 aa)
ATP6V0D1V-type proton ATPase subunit; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. Belongs to the V-ATPase V0D/AC39 subunit family. (392 aa)
HMOX2Heme oxygenase 2. (370 aa)
ATP6V0CV-type H+-transporting ATPase 16kDa proteolipid subunit. (155 aa)
IREB2Iron-responsive element-binding protein 2; Belongs to the aconitase/IPM isomerase family. (963 aa)
SLC22A17SLC22A17 isoform 1. (555 aa)
ATP6AP1ATPase H+ transporting accessory protein 1. (470 aa)
FTHL17Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. (183 aa)
ATP6V1G1V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (118 aa)
ACO1Aconitase 1, soluble; Belongs to the aconitase/IPM isomerase family. (889 aa)
ATP6V0D2V-type proton ATPase subunit; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. Belongs to the V-ATPase V0D/AC39 subunit family. (350 aa)
TFRCTransferrin receptor (P90, CD71). (760 aa)
ATP6V0E1V-type proton ATPase subunit; Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (81 aa)
STEAP4STEAP4 metalloreductase. (459 aa)
LCN2-2LCN2 isoform 5; Belongs to the calycin superfamily. Lipocalin family. (200 aa)
UBCPolyubiquitin-C; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair [...] (693 aa)
ATP6V1C1V-type proton ATPase subunit C; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (382 aa)
ATP6V1F-2V-type proton ATPase subunit F; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (119 aa)
KXD1UBA52 isoform 10. (231 aa)
FTLFerritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. (182 aa)
ENSPTRP00000060412annotation not available (156 aa)
ENSPTRP00000060867annotation not available (175 aa)
ATP6V0E2ATPase H+ transporting V0 subunit e2. (184 aa)
ENSPTRP00000062516annotation not available (459 aa)
LOC101059804Ferritin heavy chain pseudogene. (150 aa)
HEPHHEPH isoform 1; Belongs to the multicopper oxidase family. (1212 aa)
LOC104001552V-type proton ATPase subunit F pseudogene. (119 aa)
ENSPTRP00000064916annotation not available (631 aa)
ENSPTRP00000067263Ubiquitin-large subunit ribosomal protein L40e. (119 aa)
ENSPTRP00000067636annotation not available (84 aa)
SLC46A1Solute carrier family 46 (Folate transporter), member 1. (459 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
Server load: low (26%) [HD]