14 items (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	KAT2B	Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (832 aa)
	SIRT1-2	Sirtuin 1. (751 aa)
	ENSPTRP00000091402	annotation not available (93 aa)
	ENSPTRP00000089297	annotation not available (265 aa)
	CREBBP	CREB binding protein. (2442 aa)
	SIRT3	NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. (399 aa)
	LOC100616026	Thioredoxin-like. (106 aa)
	FOXO4	Forkhead box O4. (505 aa)
	FOXO3	FOXO3 isoform 1. (673 aa)
	TXN	Thioredoxin; Belongs to the thioredoxin family. (105 aa)
	TXNIP	Arrestin_C domain-containing protein. (391 aa)
	SIRT1	SIRT1 isoform 2. (751 aa)
	FOXO1	FOXO1 isoform 1. (655 aa)
	EP300	E1A binding protein p300. (2175 aa)

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CREBBP	ENSPTRP00000089297	ENSPTRP00000074980	ENSPTRP00000089297	CREB binding protein.	annotation not available	0.979
CREBBP	EP300	ENSPTRP00000074980	ENSPTRP00000024841	CREB binding protein.	E1A binding protein p300.	0.999
CREBBP	FOXO1	ENSPTRP00000074980	ENSPTRP00000009886	CREB binding protein.	FOXO1 isoform 1.	0.979
CREBBP	FOXO3	ENSPTRP00000074980	ENSPTRP00000049754	CREB binding protein.	FOXO3 isoform 1.	0.941
CREBBP	FOXO4	ENSPTRP00000074980	ENSPTRP00000059402	CREB binding protein.	Forkhead box O4.	0.959
CREBBP	KAT2B	ENSPTRP00000074980	ENSPTRP00000025331	CREB binding protein.	Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily.	0.997
CREBBP	SIRT1	ENSPTRP00000074980	ENSPTRP00000004394	CREB binding protein.	SIRT1 isoform 2.	0.565
CREBBP	SIRT1-2	ENSPTRP00000074980	ENSPTRP00000093057	CREB binding protein.	Sirtuin 1.	0.565
ENSPTRP00000089297	CREBBP	ENSPTRP00000089297	ENSPTRP00000074980	annotation not available	CREB binding protein.	0.979
ENSPTRP00000089297	EP300	ENSPTRP00000089297	ENSPTRP00000024841	annotation not available	E1A binding protein p300.	0.923
ENSPTRP00000089297	FOXO3	ENSPTRP00000089297	ENSPTRP00000049754	annotation not available	FOXO3 isoform 1.	0.734
ENSPTRP00000089297	FOXO4	ENSPTRP00000089297	ENSPTRP00000059402	annotation not available	Forkhead box O4.	0.443
ENSPTRP00000089297	KAT2B	ENSPTRP00000089297	ENSPTRP00000025331	annotation not available	Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily.	0.623
ENSPTRP00000089297	SIRT1	ENSPTRP00000089297	ENSPTRP00000004394	annotation not available	SIRT1 isoform 2.	0.872
ENSPTRP00000089297	SIRT1-2	ENSPTRP00000089297	ENSPTRP00000093057	annotation not available	Sirtuin 1.	0.872
ENSPTRP00000089297	SIRT3	ENSPTRP00000089297	ENSPTRP00000067477	annotation not available	NAD-dependent protein deacetylase; NAD-dependent protein deacetylase.	0.684
ENSPTRP00000091402	TXNIP	ENSPTRP00000091402	ENSPTRP00000002043	annotation not available	Arrestin_C domain-containing protein.	0.879
EP300	CREBBP	ENSPTRP00000024841	ENSPTRP00000074980	E1A binding protein p300.	CREB binding protein.	0.999
EP300	ENSPTRP00000089297	ENSPTRP00000024841	ENSPTRP00000089297	E1A binding protein p300.	annotation not available	0.923
EP300	FOXO1	ENSPTRP00000024841	ENSPTRP00000009886	E1A binding protein p300.	FOXO1 isoform 1.	0.923