STRINGSTRING
PSMC6 PSMC6 PSMB2 PSMB2 PRDX1 PRDX1 GCLM GCLM PSMB4 PSMB4 TALDO1 TALDO1 PSMA1 PSMA1 PSMC3 PSMC3 PSMD9 PSMD9 PSME1 PSME1 PSME2 PSME2 PSMA6 PSMA6 PSMA3 PSMA3 PSMC1 PSMC1 PSMA4 PSMA4 NQO1 NQO1 PSMD7 PSMD7 PSMD11 PSMD11 PSMD3 PSMD3 PSMD8 PSMD8 RPS27A RPS27A PSMD14 PSMD14 PSMD1 PSMD1 PSMF1 PSMF1 PSMA7 PSMA7 BACH1 BACH1 HMOX1 HMOX1 ATF4 ATF4 RBX1 RBX1 EP300 EP300 PSMD6 PSMD6 TXNRD3 TXNRD3 PSMD2 PSMD2 PSMB8 PSMB8 PSMB9 PSMB9 GSTA1 GSTA1 GCLC GCLC ME1 ME1 PSMB1 PSMB1 NFE2L3 NFE2L3 PSMC2 PSMC2 CUL1 CUL1 GSR GSR PSMB7 PSMB7 NOTCH1 NOTCH1 G6PD G6PD PSMD10 PSMD10 PSMB10 PSMB10 NFE2L1 NFE2L1 SQSTM1 SQSTM1 PSMA2 PSMA2 UBC UBC ENSPTRP00000054503 ENSPTRP00000054503 PSMC5 PSMC5 PGD PGD KXD1 KXD1 ENSPTRP00000060412 ENSPTRP00000060412 ENSPTRP00000062484 ENSPTRP00000062484 PSMD5 PSMD5 ENSPTRP00000062858 ENSPTRP00000062858 ENSPTRP00000063012 ENSPTRP00000063012 PSME3-2 PSME3-2 ENSPTRP00000064540 ENSPTRP00000064540 NFE2L2 NFE2L2 ENSPTRP00000064916 ENSPTRP00000064916 ENSPTRP00000065241 ENSPTRP00000065241 ENSPTRP00000067263 ENSPTRP00000067263 ENSPTRP00000067636 ENSPTRP00000067636 ENSPTRP00000067920 ENSPTRP00000067920 SLC7A11 SLC7A11 PSMB6 PSMB6 MAFK MAFK ENSPTRP00000068751 ENSPTRP00000068751 ENSPTRP00000069172 ENSPTRP00000069172 PSMB3 PSMB3 LOC100611078 LOC100611078 SKP1 SKP1 TXNRD1 TXNRD1 ENSPTRP00000071568 ENSPTRP00000071568 LOC470312 LOC470312 PSMD13 PSMD13 ENSPTRP00000071907 ENSPTRP00000071907 ENSPTRP00000073673 ENSPTRP00000073673 LOC100615743 LOC100615743 ENSPTRP00000074972 ENSPTRP00000074972 CREBBP CREBBP SRXN1 SRXN1 MYC MYC ENSPTRP00000076582 ENSPTRP00000076582 BTRC BTRC ENSPTRP00000077224 ENSPTRP00000077224 ENSPTRP00000077985 ENSPTRP00000077985 ENSPTRP00000078047 ENSPTRP00000078047 LOC461963 LOC461963 PSMD12 PSMD12 PSMA5 PSMA5 ENSPTRP00000080278 ENSPTRP00000080278 CK820_G0002453 CK820_G0002453 TKT TKT GSK3B GSK3B ENSPTRP00000082443 ENSPTRP00000082443 ENSPTRP00000082515 ENSPTRP00000082515 IDH1 IDH1 ENSPTRP00000084510 ENSPTRP00000084510 ENSPTRP00000084513 ENSPTRP00000084513 ENSPTRP00000085348 ENSPTRP00000085348 PSME3 PSME3 CUL1-2 CUL1-2 ENSPTRP00000086525 ENSPTRP00000086525 ENSPTRP00000086535 ENSPTRP00000086535 ENSPTRP00000086815 ENSPTRP00000086815 LOC101059795 LOC101059795 PSMC4 PSMC4 ENSPTRP00000087425 ENSPTRP00000087425 PSMB5 PSMB5 ENSPTRP00000090249 ENSPTRP00000090249 MAFG MAFG PSMD4 PSMD4 ENSPTRP00000091341 ENSPTRP00000091341
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PSMC6Proteasome (Prosome, macropain) 26S subunit, ATPase, 6; Belongs to the AAA ATPase family. (411 aa)
PSMB2Proteasome subunit beta. (201 aa)
PRDX1PRDX1 isoform 1. (199 aa)
GCLMGlutamate-cysteine ligase, modifier subunit. (274 aa)
PSMB4Proteasome subunit beta; Belongs to the peptidase T1B family. (264 aa)
TALDO1Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. (337 aa)
PSMA1Proteasome subunit alpha type. (269 aa)
PSMC3Proteasome (Prosome, macropain) 26S subunit, ATPase, 3; Belongs to the AAA ATPase family. (446 aa)
PSMD9Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 9. (223 aa)
PSME1Proteasome (Prosome, macropain) activator subunit 1 (PA28 alpha). (250 aa)
PSME2Proteasome (Prosome, macropain) activator subunit 2 (PA28 beta). (239 aa)
PSMA6Proteasome subunit alpha type. (246 aa)
PSMA3Proteasome subunit alpha type. (255 aa)
PSMC1Proteasome (Prosome, macropain) 26S subunit, ATPase, 1; Belongs to the AAA ATPase family. (440 aa)
PSMA4Proteasome subunit alpha type-4 isoform X2. (261 aa)
NQO1NAD(P)H quinone dehydrogenase 1. (274 aa)
PSMD7Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 7. (324 aa)
PSMD11Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 11. (422 aa)
PSMD3Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 3. (534 aa)
PSMD8Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 8. (350 aa)
RPS27ARPS27A isoform 1. (156 aa)
PSMD14Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 14. (310 aa)
PSMD126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (953 aa)
PSMF1Proteasome (Prosome, macropain) inhibitor subunit 1 (PI31). (271 aa)
PSMA7Proteasome subunit alpha type. (248 aa)
BACH1BTB and CNC homology 1, basic leucine zipper transcription factor 1. (736 aa)
HMOX1Heme oxygenase; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. (311 aa)
ATF4Activating transcription factor 4 (Tax-responsive enhancer element B67). (351 aa)
RBX1Ring-box 1, E3 ubiquitin protein ligase. (108 aa)
EP300E1A binding protein p300. (2175 aa)
PSMD6Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 6. (441 aa)
TXNRD3TXNRD3 isoform 1. (642 aa)
PSMD226S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (908 aa)
PSMB8Proteasome subunit beta. (276 aa)
PSMB9Proteasome subunit beta. (218 aa)
GSTA1Glutathione S-transferase. (222 aa)
GCLCGlutamate-cysteine ligase, catalytic subunit. (637 aa)
ME1Malic enzyme. (572 aa)
PSMB1Proteasome subunit beta. (241 aa)
NFE2L3Nuclear factor (Erythroid-derived 2)-like 3. (692 aa)
PSMC2Proteasome (Prosome, macropain) 26S subunit, ATPase, 2; Belongs to the AAA ATPase family. (433 aa)
CUL1CUL1 isoform 1; Belongs to the cullin family. (776 aa)
GSRGlutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. (522 aa)
PSMB7Proteasome subunit beta. (277 aa)
NOTCH1NOTCH1 isoform 1. (2555 aa)
G6PDGlucose-6-phosphate dehydrogenase. (560 aa)
PSMD10Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 10. (226 aa)
PSMB10Proteasome subunit beta type-10. (273 aa)
NFE2L1Nuclear factor (Erythroid-derived 2)-like 1. (772 aa)
SQSTM1SQSTM1 isoform 4. (440 aa)
PSMA2Proteasome subunit alpha type. (234 aa)
UBCPolyubiquitin-C; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair [...] (693 aa)
ENSPTRP00000054503annotation not available (205 aa)
PSMC5Proteasome (Prosome, macropain) 26S subunit, ATPase, 5; Belongs to the AAA ATPase family. (406 aa)
PGD6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (483 aa)
KXD1UBA52 isoform 10. (231 aa)
ENSPTRP00000060412annotation not available (156 aa)
ENSPTRP00000062484annotation not available (224 aa)
PSMD5PSMD5 isoform 1. (509 aa)
ENSPTRP00000062858annotation not available (678 aa)
ENSPTRP00000063012annotation not available (405 aa)
PSME3-2Proteasome activator subunit 3. (265 aa)
ENSPTRP00000064540annotation not available (358 aa)
NFE2L2Nuclear factor (Erythroid-derived 2)-like 2. (605 aa)
ENSPTRP00000064916annotation not available (631 aa)
ENSPTRP00000065241annotation not available (350 aa)
ENSPTRP00000067263Ubiquitin-large subunit ribosomal protein L40e. (119 aa)
ENSPTRP00000067636annotation not available (84 aa)
ENSPTRP00000067920annotation not available (392 aa)
SLC7A11Solute carrier family 7, (Cationic amino acid transporter, y+ system) member 11. (515 aa)
PSMB6Proteasome subunit beta. (244 aa)
MAFKV-maf musculoaponeurotic fibrosarcoma oncogene homolog K (Avian). (156 aa)
ENSPTRP00000068751annotation not available (394 aa)
ENSPTRP00000069172annotation not available (353 aa)
PSMB3Proteasome subunit beta. (205 aa)
LOC100611078Cyclic AMP-dependent transcription factor ATF-4 pseudogene. (318 aa)
SKP1T0093123 isoform 1; Belongs to the SKP1 family. (163 aa)
TXNRD1TXNRD1 isoform 3. (648 aa)
ENSPTRP00000071568annotation not available (98 aa)
LOC47031226S proteasome regulatory subunit 4 pseudogene. (374 aa)
PSMD13Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 13. (399 aa)
ENSPTRP00000071907annotation not available (164 aa)
ENSPTRP00000073673annotation not available (196 aa)
LOC100615743Peroxiredoxin-1-like. (171 aa)
ENSPTRP00000074972annotation not available (252 aa)
CREBBPCREB binding protein. (2442 aa)
SRXN1Sulfiredoxin. (165 aa)
MYCMyc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. Binds to the VEGFA promoter, promoting VEGFA production and subsequent sprouting angiogenesis. Regulator of somatic reprogramming, controls self-renewal of embryonic stem cells. Functions with TAF6L to activate target gene expression through RNA polymerase II pause release (By similarity). (454 aa)
ENSPTRP00000076582annotation not available (377 aa)
BTRCBeta-transducin repeat containing E3 ubiquitin protein ligase. (605 aa)
ENSPTRP00000077224annotation not available (84 aa)
ENSPTRP00000077985annotation not available (153 aa)
ENSPTRP00000078047annotation not available (132 aa)
LOC461963PSME2 isoform 10. (224 aa)
PSMD12Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 12. (480 aa)
PSMA5Proteasome subunit alpha type. (241 aa)
ENSPTRP00000080278annotation not available (136 aa)
CK820_G0002453PSMC6 isoform 12. (340 aa)
TKTTransketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (631 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (481 aa)
ENSPTRP00000082443annotation not available (351 aa)
ENSPTRP00000082515annotation not available (336 aa)
IDH1Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (424 aa)
ENSPTRP00000084510annotation not available (456 aa)
ENSPTRP00000084513annotation not available (205 aa)
ENSPTRP00000085348annotation not available (302 aa)
PSME3Proteasome activator subunit 3. (265 aa)
CUL1-2Cullin 1. (776 aa)
ENSPTRP00000086525annotation not available (336 aa)
ENSPTRP00000086535annotation not available (351 aa)
ENSPTRP00000086815annotation not available (145 aa)
LOC10105979526S proteasome non-ATPase regulatory subunit 2 pseudogene. (829 aa)
PSMC4Proteasome (Prosome, macropain) 26S subunit, ATPase, 4; Belongs to the AAA ATPase family. (421 aa)
ENSPTRP00000087425annotation not available (336 aa)
PSMB5Proteasome subunit beta. (263 aa)
ENSPTRP00000090249annotation not available (96 aa)
MAFGV-maf musculoaponeurotic fibrosarcoma oncogene homolog G (Avian). (162 aa)
PSMD4PSMD4 isoform 2. (382 aa)
ENSPTRP00000091341annotation not available (379 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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