22 items (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ATF4	Activating transcription factor 4 (Tax-responsive enhancer element B67). (351 aa)
	HMOX1	Heme oxygenase; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. (311 aa)
	TXNRD1	TXNRD1 isoform 3. (648 aa)
	LOC100615743	Peroxiredoxin-1-like. (171 aa)
	CREBBP	CREB binding protein. (2442 aa)
	SRXN1	Sulfiredoxin. (165 aa)
	ENSPTRP00000082515	annotation not available (336 aa)
	ENSPTRP00000086525	annotation not available (336 aa)
	ENSPTRP00000087425	annotation not available (336 aa)
	MAFK	V-maf musculoaponeurotic fibrosarcoma oncogene homolog K (Avian). (156 aa)
	SLC7A11	Solute carrier family 7, (Cationic amino acid transporter, y+ system) member 11. (515 aa)
	NFE2L2	Nuclear factor (Erythroid-derived 2)-like 2. (605 aa)
	GSR	Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. (522 aa)
	GCLC	Glutamate-cysteine ligase, catalytic subunit. (637 aa)
	GSTA1	Glutathione S-transferase. (222 aa)
	TXNRD3	TXNRD3 isoform 1. (642 aa)
	PRDX1	PRDX1 isoform 1. (199 aa)
	GCLM	Glutamate-cysteine ligase, modifier subunit. (274 aa)
	NQO1	NAD(P)H quinone dehydrogenase 1. (274 aa)
	BACH1	BTB and CNC homology 1, basic leucine zipper transcription factor 1. (736 aa)
	EP300	E1A binding protein p300. (2175 aa)
	LOC100611078	Cyclic AMP-dependent transcription factor ATF-4 pseudogene. (318 aa)

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATF4	CREBBP	ENSPTRP00000024806	ENSPTRP00000074980	Activating transcription factor 4 (Tax-responsive enhancer element B67).	CREB binding protein.	0.980
ATF4	ENSPTRP00000082515	ENSPTRP00000024806	ENSPTRP00000082515	Activating transcription factor 4 (Tax-responsive enhancer element B67).	annotation not available	0.545
ATF4	ENSPTRP00000086525	ENSPTRP00000024806	ENSPTRP00000086525	Activating transcription factor 4 (Tax-responsive enhancer element B67).	annotation not available	0.545
ATF4	ENSPTRP00000087425	ENSPTRP00000024806	ENSPTRP00000087425	Activating transcription factor 4 (Tax-responsive enhancer element B67).	annotation not available	0.545
ATF4	EP300	ENSPTRP00000024806	ENSPTRP00000024841	Activating transcription factor 4 (Tax-responsive enhancer element B67).	E1A binding protein p300.	0.980
ATF4	GCLM	ENSPTRP00000024806	ENSPTRP00000001677	Activating transcription factor 4 (Tax-responsive enhancer element B67).	Glutamate-cysteine ligase, modifier subunit.	0.459
ATF4	HMOX1	ENSPTRP00000024806	ENSPTRP00000024624	Activating transcription factor 4 (Tax-responsive enhancer element B67).	Heme oxygenase; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase.	0.501
ATF4	LOC100611078	ENSPTRP00000024806	ENSPTRP00000069696	Activating transcription factor 4 (Tax-responsive enhancer element B67).	Cyclic AMP-dependent transcription factor ATF-4 pseudogene.	0.545
ATF4	NFE2L2	ENSPTRP00000024806	ENSPTRP00000064585	Activating transcription factor 4 (Tax-responsive enhancer element B67).	Nuclear factor (Erythroid-derived 2)-like 2.	0.692
ATF4	SLC7A11	ENSPTRP00000024806	ENSPTRP00000068169	Activating transcription factor 4 (Tax-responsive enhancer element B67).	Solute carrier family 7, (Cationic amino acid transporter, y+ system) member 11.	0.402
BACH1	HMOX1	ENSPTRP00000023815	ENSPTRP00000024624	BTB and CNC homology 1, basic leucine zipper transcription factor 1.	Heme oxygenase; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase.	0.777
BACH1	MAFK	ENSPTRP00000023815	ENSPTRP00000068693	BTB and CNC homology 1, basic leucine zipper transcription factor 1.	V-maf musculoaponeurotic fibrosarcoma oncogene homolog K (Avian).	0.981
CREBBP	ATF4	ENSPTRP00000074980	ENSPTRP00000024806	CREB binding protein.	Activating transcription factor 4 (Tax-responsive enhancer element B67).	0.980
CREBBP	ENSPTRP00000082515	ENSPTRP00000074980	ENSPTRP00000082515	CREB binding protein.	annotation not available	0.648
CREBBP	ENSPTRP00000086525	ENSPTRP00000074980	ENSPTRP00000086525	CREB binding protein.	annotation not available	0.648
CREBBP	ENSPTRP00000087425	ENSPTRP00000074980	ENSPTRP00000087425	CREB binding protein.	annotation not available	0.648
CREBBP	EP300	ENSPTRP00000074980	ENSPTRP00000024841	CREB binding protein.	E1A binding protein p300.	0.999
CREBBP	LOC100611078	ENSPTRP00000074980	ENSPTRP00000069696	CREB binding protein.	Cyclic AMP-dependent transcription factor ATF-4 pseudogene.	0.810
CREBBP	MAFK	ENSPTRP00000074980	ENSPTRP00000068693	CREB binding protein.	V-maf musculoaponeurotic fibrosarcoma oncogene homolog K (Avian).	0.446
CREBBP	NFE2L2	ENSPTRP00000074980	ENSPTRP00000064585	CREB binding protein.	Nuclear factor (Erythroid-derived 2)-like 2.	0.836