STRINGSTRING
PIK3CD PIK3CD CK820_G0052109 CK820_G0052109 ENSPTRP00000092307 ENSPTRP00000092307 BANK1 BANK1 ENSPTRP00000089740 ENSPTRP00000089740 CK820_G0052139 CK820_G0052139 ENSPTRP00000085718 ENSPTRP00000085718 CK820_G0055133 CK820_G0055133 TRPC1 TRPC1 SH3KBP1 SH3KBP1 CD19 CD19 CK820_G0052121 CK820_G0052121 ORAI2 ORAI2 ORAI3 ORAI3 CK820_G0055030 CK820_G0055030 FYN FYN STIM1 STIM1 PIK3R1 PIK3R1 PLCG2 PLCG2 STIM2 STIM2 SYK SYK CK820_G0056252 CK820_G0056252 CK820_G0054782 CK820_G0054782 ENSPTRP00000072507 ENSPTRP00000072507 ENSPTRP00000070755 ENSPTRP00000070755 ORAI2-2 ORAI2-2 ENSPTRP00000067835 ENSPTRP00000067835 AHCYL1 AHCYL1 ENSPTRP00000065882 ENSPTRP00000065882 LOC744594 LOC744594 CK820_G0052128 CK820_G0052128 IGLL5 IGLL5 LOC452776 LOC452776 CK820_G0055106 CK820_G0055106 CK820_G0055055 CK820_G0055055 IGKV1D-43 IGKV1D-43 SOS1 SOS1 ENSPTRP00000050833 ENSPTRP00000050833 PTPN6 PTPN6 BLK BLK LYN LYN BTK BTK ITPR3 ITPR3 DAPP1 DAPP1 NCK1 NCK1 ITPR1 ITPR1 ITPR2 ITPR2 CK820_G0046006 CK820_G0046006 CALM3 CALM3 CD79A CD79A CD22 CD22 VAV1 VAV1 GRB2 GRB2 CD79B CD79B ORAI1 ORAI1 PIK3AP1 PIK3AP1 BLNK BLNK
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
CK820_G0052109IGLV3-1 isoform 1. (166 aa)
ENSPTRP00000092307annotation not available (161 aa)
BANK1B cell scaffold protein with ankyrin repeats 1. (785 aa)
ENSPTRP00000089740annotation not available (123 aa)
CK820_G0052139IGLV2-23 isoform 1. (170 aa)
ENSPTRP00000085718annotation not available (180 aa)
CK820_G0055133IGHD isoform 2. (577 aa)
TRPC1TRPC1 isoform 3; Belongs to the transient receptor (TC 1.A.4) family. (795 aa)
SH3KBP1SH3KBP1 isoform 2. (665 aa)
CD19CD19 isoform 1. (557 aa)
CK820_G0052121IGLV3-10 isoform 1. (148 aa)
ORAI2ORAI calcium release-activated calcium modulator 2. (262 aa)
ORAI3ORAI calcium release-activated calcium modulator 3. (295 aa)
CK820_G0055030IGHV1-2 isoform 1. (159 aa)
FYNTyrosine-protein kinase. (537 aa)
STIM1Stromal interaction molecule 1. (791 aa)
PIK3R1Phosphoinositide-3-kinase, regulatory subunit 1 (Alpha). (724 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1265 aa)
STIM2STIM2 isoform 3. (841 aa)
SYKTyrosine-protein kinase. (635 aa)
CK820_G0056252IGHV3-30 isoform 1. (198 aa)
CK820_G0054782IGLV9-49 isoform 1. (123 aa)
ENSPTRP00000072507annotation not available (659 aa)
ENSPTRP00000070755annotation not available (81 aa)
ORAI2-2ORAI calcium release-activated calcium modulator 2. (262 aa)
ENSPTRP00000067835annotation not available (192 aa)
AHCYL1Adenosylhomocysteinase. (499 aa)
ENSPTRP00000065882annotation not available (152 aa)
LOC744594IGHV4-61 isoform 1. (215 aa)
CK820_G0052128IGLV2-14 isoform 1. (170 aa)
IGLL5IGLL5 isoform 1. (215 aa)
LOC452776TRAV22 isoform 1. (185 aa)
CK820_G0055106IGHV3-66 isoform 1. (181 aa)
CK820_G0055055IGHV2-26 isoform 1. (178 aa)
IGKV1D-43IGKV1-39 isoform 1. (125 aa)
SOS1SOS Ras/Rac guanine nucleotide exchange factor 1. (1333 aa)
ENSPTRP00000050833annotation not available (151 aa)
PTPN6Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (597 aa)
BLKTyrosine-protein kinase. (505 aa)
LYNTyrosine-protein kinase. (512 aa)
BTKBTK isoform 2. (693 aa)
ITPR3ITPR3 isoform 1. (2677 aa)
DAPP1Dual adaptor of phosphotyrosine and 3-phosphoinositides 1. (280 aa)
NCK1Cytoplasmic protein. (377 aa)
ITPR1ITPR1 isoform 3. (2700 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor, type 2. (2727 aa)
CK820_G0046006IGKV2-40 isoform 1. (122 aa)
CALM3Calmodulin 1 (Phosphorylase kinase, delta); Belongs to the calmodulin family. (149 aa)
CD79ACD79A isoform 1. (226 aa)
CD22B-cell receptor CD22; Mediates B-cell B-cell interactions. May be involved in the localization of B-cells in lymphoid tissues. Binds sialylated glycoproteins; one of which is CD45. Preferentially binds to alpha-2,6- linked sialic acid (By similarity). Upon ligand-induced tyrosine phosphorylation in the immune response seems to be involved in regulation of B-cell antigen receptor signaling. Plays a role in positive regulation through interaction with Src family tyrosine kinases and may also act as an inhibitory receptor by recruiting cytoplasmic phosphatases via their SH2 domains that b [...] (847 aa)
VAV1Vav guanine nucleotide exchange factor 1. (845 aa)
GRB2Growth factor receptor-bound protein 2. (217 aa)
CD79BCD79B isoform 2. (230 aa)
ORAI1ORAI1 isoform 1. (301 aa)
PIK3AP1Phosphoinositide-3-kinase adaptor protein 1. (805 aa)
BLNKBLNK isoform 2. (456 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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