STRINGSTRING
ENSPTRP00000085348 ENSPTRP00000085348 CK820_G0055030 CK820_G0055030 FYN FYN STIM1 STIM1 ENSPTRP00000077224 ENSPTRP00000077224 BTRC BTRC PIK3R1 PIK3R1 ENSPTRP00000076582 ENSPTRP00000076582 PLCG2 PLCG2 LOC100610002 LOC100610002 STIM2 STIM2 ENSPTRP00000074972 ENSPTRP00000074972 SYK SYK ENSPTRP00000073673 ENSPTRP00000073673 RASGRP1 RASGRP1 CK820_G0056252 CK820_G0056252 CK820_G0054782 CK820_G0054782 ENSPTRP00000072507 ENSPTRP00000072507 ENSPTRP00000071907 ENSPTRP00000071907 PSMD13 PSMD13 LOC470312 LOC470312 ENSPTRP00000071568 ENSPTRP00000071568 CSDE1 CSDE1 ENSPTRP00000070755 ENSPTRP00000070755 ENSPTRP00000070633 ENSPTRP00000070633 LOC100612002 LOC100612002 SKP1 SKP1 ORAI2-2 ORAI2-2 PSMB3 PSMB3 ENSPTRP00000069172 ENSPTRP00000069172 ENSPTRP00000068616 ENSPTRP00000068616 PSMB6 PSMB6 ENSPTRP00000067920 ENSPTRP00000067920 ENSPTRP00000067835 ENSPTRP00000067835 PPP3CA PPP3CA ENSPTRP00000067636 ENSPTRP00000067636 ENSPTRP00000067263 ENSPTRP00000067263 AHCYL1 AHCYL1 ENSPTRP00000065882 ENSPTRP00000065882 NFATC1 NFATC1 LOC744594 LOC744594 ENSPTRP00000065241 ENSPTRP00000065241 ENSPTRP00000064916 ENSPTRP00000064916 PPP3CB PPP3CB ERAS ERAS ENSPTRP00000064540 ENSPTRP00000064540 CCDC71L CCDC71L PSME3-2 PSME3-2 PSMD5 PSMD5 CK820_G0052128 CK820_G0052128 ENSPTRP00000062484 ENSPTRP00000062484 CK820_G0040557 CK820_G0040557 IGLL5 IGLL5 LOC452776 LOC452776 ENSPTRP00000060412 ENSPTRP00000060412 KXD1 KXD1 CK820_G0055106 CK820_G0055106 CK820_G0055055 CK820_G0055055 NFKBIB NFKBIB MAP3K7 MAP3K7 PSMC5 PSMC5 ENSPTRP00000054503 ENSPTRP00000054503 RELA RELA IGKV1D-43 IGKV1D-43 SOS1 SOS1 UBC UBC ENSPTRP00000050833 ENSPTRP00000050833 PTPN6 PTPN6 BLK BLK PSMA2 PSMA2 NFATC2 NFATC2 LYN LYN PSMB10 PSMB10 PSMD10 PSMD10 BTK BTK PSMB7 PSMB7 IKBKB IKBKB CUL1 CUL1 PSMC2 PSMC2 PSMB1 PSMB1 NFKBIE NFKBIE ITPR3 ITPR3 PSMB9 PSMB9 PSMB8 PSMB8 NFKB1 NFKB1 DAPP1 DAPP1 PSMD2 PSMD2 NCK1 NCK1 PSMD6 PSMD6 ITPR1 ITPR1 ITPR2 ITPR2 CK820_G0046006 CK820_G0046006 PSMA7 PSMA7 FKBP1A FKBP1A PSMF1 PSMF1 PSMD1 PSMD1 PSMD14 PSMD14 PPP3R1 PPP3R1 RPS27A RPS27A RASGRP3 RASGRP3 CALM3 CALM3 CD79A CD79A PSMD8 PSMD8 CD22 CD22 VAV1 VAV1 MALT1 MALT1 PSMA8 PSMA8 GRB2 GRB2 CD79B CD79B PSMD3 PSMD3 PSMD11 PSMD11 NFATC3 NFATC3 PSMC4 PSMC4 LOC101059795 LOC101059795 ENSPTRP00000086815 ENSPTRP00000086815 ENSPTRP00000086535 ENSPTRP00000086535 CUL1-2 CUL1-2 REL REL ENSPTRP00000085718 ENSPTRP00000085718 PSME3 PSME3 CARD11 CARD11 CK820_G0055133 CK820_G0055133 NFAT5 NFAT5 KRAS KRAS ENSPTRP00000084513 ENSPTRP00000084513 CHUK CHUK TRPC1 TRPC1 PSME4 PSME4 SH3KBP1 SH3KBP1 ENSPTRP00000082443 ENSPTRP00000082443 IKBKG IKBKG ENSPTRP00000081587 ENSPTRP00000081587 ENSPTRP00000081523 ENSPTRP00000081523 CK820_G0002453 CK820_G0002453 ENSPTRP00000080278 ENSPTRP00000080278 PSMA5 PSMA5 PSMD12 PSMD12 CD19 CD19 PPIA PPIA LOC461963 LOC461963 CK820_G0052121 CK820_G0052121 ORAI2 ORAI2 ORAI3 ORAI3 FBXW11 FBXW11 ENSPTRP00000078047 ENSPTRP00000078047 ENSPTRP00000077985 ENSPTRP00000077985 PSMD7 PSMD7 PRKCB PRKCB PSMA4 PSMA4 PSMC1 PSMC1 PSMA3 PSMA3 NFKBIA NFKBIA PSMA6 PSMA6 PSME2 PSME2 PSME1 PSME1 PSMD9 PSMD9 ORAI1 ORAI1 PSMC3 PSMC3 PSMA1 PSMA1 HRAS HRAS PIK3AP1 PIK3AP1 BLNK BLNK PSMB4 PSMB4 NRAS NRAS BCL10 BCL10 PSMB2 PSMB2 PIK3CD PIK3CD BANK1 BANK1 ENSPTRP00000091341 ENSPTRP00000091341 PSMD4 PSMD4 LOC473924 LOC473924 ENSPTRP00000090249 ENSPTRP00000090249 ENSPTRP00000087988 ENSPTRP00000087988 ENSPTRP00000089740 ENSPTRP00000089740 PSMC6 PSMC6 PSMB5 PSMB5 CK820_G0052139 CK820_G0052139 CK820_G0052109 CK820_G0052109 LOC107968189 LOC107968189 ENSPTRP00000092307 ENSPTRP00000092307 ENSPTRP00000091883 ENSPTRP00000091883
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSPTRP00000085348annotation not available (302 aa)
CK820_G0055030IGHV1-2 isoform 1. (159 aa)
FYNTyrosine-protein kinase. (537 aa)
STIM1Stromal interaction molecule 1. (791 aa)
ENSPTRP00000077224annotation not available (84 aa)
BTRCBeta-transducin repeat containing E3 ubiquitin protein ligase. (605 aa)
PIK3R1Phosphoinositide-3-kinase, regulatory subunit 1 (Alpha). (724 aa)
ENSPTRP00000076582annotation not available (377 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1265 aa)
LOC100610002IKBKG isoform 9. (401 aa)
STIM2STIM2 isoform 3. (841 aa)
ENSPTRP00000074972annotation not available (252 aa)
SYKTyrosine-protein kinase. (635 aa)
ENSPTRP00000073673annotation not available (196 aa)
RASGRP1RASGRP1 isoform 4. (848 aa)
CK820_G0056252IGHV3-30 isoform 1. (198 aa)
CK820_G0054782IGLV9-49 isoform 1. (123 aa)
ENSPTRP00000072507annotation not available (659 aa)
ENSPTRP00000071907annotation not available (164 aa)
PSMD13Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 13. (399 aa)
LOC47031226S proteasome regulatory subunit 4 pseudogene. (374 aa)
ENSPTRP00000071568annotation not available (98 aa)
CSDE1Cold shock domain containing E1. (844 aa)
ENSPTRP00000070755annotation not available (81 aa)
ENSPTRP00000070633annotation not available (178 aa)
LOC100612002Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (158 aa)
SKP1T0093123 isoform 1; Belongs to the SKP1 family. (163 aa)
ORAI2-2ORAI calcium release-activated calcium modulator 2. (262 aa)
PSMB3Proteasome subunit beta. (205 aa)
ENSPTRP00000069172annotation not available (353 aa)
ENSPTRP00000068616annotation not available (157 aa)
PSMB6Proteasome subunit beta. (244 aa)
ENSPTRP00000067920annotation not available (392 aa)
ENSPTRP00000067835annotation not available (192 aa)
PPP3CASerine/threonine-protein phosphatase. (521 aa)
ENSPTRP00000067636annotation not available (84 aa)
ENSPTRP00000067263Ubiquitin-large subunit ribosomal protein L40e. (119 aa)
AHCYL1Adenosylhomocysteinase. (499 aa)
ENSPTRP00000065882annotation not available (152 aa)
NFATC1Nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1. (853 aa)
LOC744594IGHV4-61 isoform 1. (215 aa)
ENSPTRP00000065241annotation not available (350 aa)
ENSPTRP00000064916annotation not available (631 aa)
PPP3CBSerine/threonine-protein phosphatase. (526 aa)
ERASES cell expressed Ras. (233 aa)
ENSPTRP00000064540annotation not available (358 aa)
CCDC71LCCDC71L isoform 2. (311 aa)
PSME3-2Proteasome activator subunit 3. (265 aa)
PSMD5PSMD5 isoform 1. (509 aa)
CK820_G0052128IGLV2-14 isoform 1. (170 aa)
ENSPTRP00000062484annotation not available (224 aa)
CK820_G0040557Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (158 aa)
IGLL5IGLL5 isoform 1. (215 aa)
LOC452776TRAV22 isoform 1. (185 aa)
ENSPTRP00000060412annotation not available (156 aa)
KXD1UBA52 isoform 10. (231 aa)
CK820_G0055106IGHV3-66 isoform 1. (181 aa)
CK820_G0055055IGHV2-26 isoform 1. (178 aa)
NFKBIBNFKB inhibitor beta. (270 aa)
MAP3K7Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa)
PSMC5Proteasome (Prosome, macropain) 26S subunit, ATPase, 5; Belongs to the AAA ATPase family. (406 aa)
ENSPTRP00000054503annotation not available (205 aa)
RELAV-rel reticuloendotheliosis viral oncogene homolog A (Avian). (551 aa)
IGKV1D-43IGKV1-39 isoform 1. (125 aa)
SOS1SOS Ras/Rac guanine nucleotide exchange factor 1. (1333 aa)
UBCPolyubiquitin-C; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair [...] (693 aa)
ENSPTRP00000050833annotation not available (151 aa)
PTPN6Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (597 aa)
BLKTyrosine-protein kinase. (505 aa)
PSMA2Proteasome subunit alpha type. (234 aa)
NFATC2NFATC2 isoform 4. (938 aa)
LYNTyrosine-protein kinase. (512 aa)
PSMB10Proteasome subunit beta type-10. (273 aa)
PSMD10Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 10. (226 aa)
BTKBTK isoform 2. (693 aa)
PSMB7Proteasome subunit beta. (277 aa)
IKBKBInhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta. (763 aa)
CUL1CUL1 isoform 1; Belongs to the cullin family. (776 aa)
PSMC2Proteasome (Prosome, macropain) 26S subunit, ATPase, 2; Belongs to the AAA ATPase family. (433 aa)
PSMB1Proteasome subunit beta. (241 aa)
NFKBIENFKB inhibitor epsilon. (500 aa)
ITPR3ITPR3 isoform 1. (2677 aa)
PSMB9Proteasome subunit beta. (218 aa)
PSMB8Proteasome subunit beta. (276 aa)
NFKB1Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1. (969 aa)
DAPP1Dual adaptor of phosphotyrosine and 3-phosphoinositides 1. (280 aa)
PSMD226S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (908 aa)
NCK1Cytoplasmic protein. (377 aa)
PSMD6Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 6. (441 aa)
ITPR1ITPR1 isoform 3. (2700 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor, type 2. (2727 aa)
CK820_G0046006IGKV2-40 isoform 1. (122 aa)
PSMA7Proteasome subunit alpha type. (248 aa)
FKBP1APeptidylprolyl isomerase. (139 aa)
PSMF1Proteasome (Prosome, macropain) inhibitor subunit 1 (PI31). (271 aa)
PSMD126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (953 aa)
PSMD14Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 14. (310 aa)
PPP3R1WD repeat domain 92. (753 aa)
RPS27ARPS27A isoform 1. (156 aa)
RASGRP3RAS guanyl releasing protein 3. (690 aa)
CALM3Calmodulin 1 (Phosphorylase kinase, delta); Belongs to the calmodulin family. (149 aa)
CD79ACD79A isoform 1. (226 aa)
PSMD8Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 8. (350 aa)
CD22B-cell receptor CD22; Mediates B-cell B-cell interactions. May be involved in the localization of B-cells in lymphoid tissues. Binds sialylated glycoproteins; one of which is CD45. Preferentially binds to alpha-2,6- linked sialic acid (By similarity). Upon ligand-induced tyrosine phosphorylation in the immune response seems to be involved in regulation of B-cell antigen receptor signaling. Plays a role in positive regulation through interaction with Src family tyrosine kinases and may also act as an inhibitory receptor by recruiting cytoplasmic phosphatases via their SH2 domains that b [...] (847 aa)
VAV1Vav guanine nucleotide exchange factor 1. (845 aa)
MALT1Mucosa associated lymphoid tissue lymphoma translocation gene 1. (824 aa)
PSMA8Proteasome subunit alpha type. (256 aa)
GRB2Growth factor receptor-bound protein 2. (217 aa)
CD79BCD79B isoform 2. (230 aa)
PSMD3Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 3. (534 aa)
PSMD11Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 11. (422 aa)
NFATC3Nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3. (1075 aa)
PSMC4Proteasome (Prosome, macropain) 26S subunit, ATPase, 4; Belongs to the AAA ATPase family. (421 aa)
LOC10105979526S proteasome non-ATPase regulatory subunit 2 pseudogene. (829 aa)
ENSPTRP00000086815annotation not available (145 aa)
ENSPTRP00000086535annotation not available (351 aa)
CUL1-2Cullin 1. (776 aa)
RELREL isoform 1. (619 aa)
ENSPTRP00000085718annotation not available (180 aa)
PSME3Proteasome activator subunit 3. (265 aa)
CARD11Caspase recruitment domain family, member 11. (1154 aa)
CK820_G0055133IGHD isoform 2. (577 aa)
NFAT5Nuclear factor of activated T-cells 5, tonicity-responsive. (1548 aa)
KRASV-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog. (189 aa)
ENSPTRP00000084513annotation not available (205 aa)
CHUKComponent of inhibitor of nuclear factor kappa B kinase complex. (760 aa)
TRPC1TRPC1 isoform 3; Belongs to the transient receptor (TC 1.A.4) family. (795 aa)
PSME4Proteasome (Prosome, macropain) activator subunit 4. (1844 aa)
SH3KBP1SH3KBP1 isoform 2. (665 aa)
ENSPTRP00000082443annotation not available (351 aa)
IKBKGInhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (487 aa)
ENSPTRP00000081587annotation not available (103 aa)
ENSPTRP00000081523annotation not available (174 aa)
CK820_G0002453PSMC6 isoform 12. (340 aa)
ENSPTRP00000080278annotation not available (136 aa)
PSMA5Proteasome subunit alpha type. (241 aa)
PSMD12Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 12. (480 aa)
CD19CD19 isoform 1. (557 aa)
PPIAPeptidyl-prolyl cis-trans isomerase A, N-terminally processed; PPIase that catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and may therefore assist protein folding; Belongs to the cyclophilin-type PPIase family. PPIase A subfamily. (165 aa)
LOC461963PSME2 isoform 10. (224 aa)
CK820_G0052121IGLV3-10 isoform 1. (148 aa)
ORAI2ORAI calcium release-activated calcium modulator 2. (262 aa)
ORAI3ORAI calcium release-activated calcium modulator 3. (295 aa)
FBXW11F-box and WD repeat domain containing 11. (563 aa)
ENSPTRP00000078047annotation not available (132 aa)
ENSPTRP00000077985annotation not available (153 aa)
PSMD7Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 7. (324 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa)
PSMA4Proteasome subunit alpha type-4 isoform X2. (261 aa)
PSMC1Proteasome (Prosome, macropain) 26S subunit, ATPase, 1; Belongs to the AAA ATPase family. (440 aa)
PSMA3Proteasome subunit alpha type. (255 aa)
NFKBIANuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha. (317 aa)
PSMA6Proteasome subunit alpha type. (246 aa)
PSME2Proteasome (Prosome, macropain) activator subunit 2 (PA28 beta). (239 aa)
PSME1Proteasome (Prosome, macropain) activator subunit 1 (PA28 alpha). (250 aa)
PSMD9Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 9. (223 aa)
ORAI1ORAI1 isoform 1. (301 aa)
PSMC3Proteasome (Prosome, macropain) 26S subunit, ATPase, 3; Belongs to the AAA ATPase family. (446 aa)
PSMA1Proteasome subunit alpha type. (269 aa)
HRASV-Ha-ras Harvey rat sarcoma viral oncogene homolog. (189 aa)
PIK3AP1Phosphoinositide-3-kinase adaptor protein 1. (805 aa)
BLNKBLNK isoform 2. (456 aa)
PSMB4Proteasome subunit beta; Belongs to the peptidase T1B family. (264 aa)
NRASNeuroblastoma RAS viral (V-ras) oncogene homolog. (189 aa)
BCL10B-cell CLL/lymphoma 10. (316 aa)
PSMB2Proteasome subunit beta. (201 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
BANK1B cell scaffold protein with ankyrin repeats 1. (785 aa)
ENSPTRP00000091341annotation not available (379 aa)
PSMD4PSMD4 isoform 2. (382 aa)
LOC473924Peptidylprolyl isomerase A pseudogene. (105 aa)
ENSPTRP00000090249annotation not available (96 aa)
ENSPTRP00000087988annotation not available (165 aa)
ENSPTRP00000089740annotation not available (123 aa)
PSMC6Proteasome (Prosome, macropain) 26S subunit, ATPase, 6; Belongs to the AAA ATPase family. (411 aa)
PSMB5Proteasome subunit beta. (263 aa)
CK820_G0052139IGLV2-23 isoform 1. (170 aa)
CK820_G0052109IGLV3-1 isoform 1. (166 aa)
LOC107968189Peptidyl-prolyl cis-trans isomerase A pseudogene. (173 aa)
ENSPTRP00000092307annotation not available (161 aa)
ENSPTRP00000091883annotation not available (155 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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