(8 nodes) APOBEC-like C-terminal domain network (Pan troglodytes)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	APOBEC3A	Apolipoprotein B mRNA editing enzyme catalytic subunit 3B. (490 aa)
	AICDA	Activation induced cytidine deaminase. (199 aa)
	LOC470275	APOBEC3F isoform 1. (373 aa)
	APOBEC3H	APOBEC3H isoform 3. (200 aa)
	APOBEC3D	Apolipoprotein B mRNA editing enzyme catalytic subunit 3D. (394 aa)
	APOBEC2	Apolipoprotein B mRNA editing enzyme catalytic subunit 2. (230 aa)
	APOBEC3G	DNA dC->dU-editing enzyme APOBEC-3G; DNA deaminase (cytidine deaminase) which acts as an inhibitor of retrovirus replication and retrotransposon mobility via deaminase- dependent and -independent mechanisms. Exhibits antiviral activity against vif-deficient: HIV-1 and simian immunodeficiency viruses (SIVs) and also against simian foamy virus (SFV). After the penetration of retroviral nucleocapsids into target cells of infection and the initiation of reverse transcription, it can induce the conversion of cytosine to uracil in the minus-sense single-strand viral DNA, leading to G-to-A hy [...] (384 aa)
	APOBEC1	APOBEC1 isoform 2. (236 aa)

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APOBEC1	APOBEC2	ENSPTRP00000007882	ENSPTRP00000050168	APOBEC1 isoform 2.	Apolipoprotein B mRNA editing enzyme catalytic subunit 2.	0.617
APOBEC1	APOBEC3H	ENSPTRP00000007882	ENSPTRP00000083401	APOBEC1 isoform 2.	APOBEC3H isoform 3.	0.411
APOBEC1	LOC470275	ENSPTRP00000007882	ENSPTRP00000090414	APOBEC1 isoform 2.	APOBEC3F isoform 1.	0.476
APOBEC2	APOBEC1	ENSPTRP00000050168	ENSPTRP00000007882	Apolipoprotein B mRNA editing enzyme catalytic subunit 2.	APOBEC1 isoform 2.	0.617
APOBEC2	APOBEC3A	ENSPTRP00000050168	ENSPTRP00000024776	Apolipoprotein B mRNA editing enzyme catalytic subunit 2.	Apolipoprotein B mRNA editing enzyme catalytic subunit 3B.	0.422
APOBEC2	APOBEC3G	ENSPTRP00000050168	ENSPTRP00000024786	Apolipoprotein B mRNA editing enzyme catalytic subunit 2.	DNA dC->dU-editing enzyme APOBEC-3G; DNA deaminase (cytidine deaminase) which acts as an inhibitor of retrovirus replication and retrotransposon mobility via deaminase- dependent and -independent mechanisms. Exhibits antiviral activity against vif-deficient: HIV-1 and simian immunodeficiency viruses (SIVs) and also against simian foamy virus (SFV). After the penetration of retroviral nucleocapsids into target cells of infection and the initiation of reverse transcription, it can induce the conversion of cytosine to uracil in the minus-sense single-strand viral DNA, leading to G-to-A hy [...]	0.438
APOBEC2	APOBEC3H	ENSPTRP00000050168	ENSPTRP00000083401	Apolipoprotein B mRNA editing enzyme catalytic subunit 2.	APOBEC3H isoform 3.	0.433
APOBEC2	LOC470275	ENSPTRP00000050168	ENSPTRP00000090414	Apolipoprotein B mRNA editing enzyme catalytic subunit 2.	APOBEC3F isoform 1.	0.422
APOBEC3A	APOBEC2	ENSPTRP00000024776	ENSPTRP00000050168	Apolipoprotein B mRNA editing enzyme catalytic subunit 3B.	Apolipoprotein B mRNA editing enzyme catalytic subunit 2.	0.422
APOBEC3G	APOBEC2	ENSPTRP00000024786	ENSPTRP00000050168	DNA dC->dU-editing enzyme APOBEC-3G; DNA deaminase (cytidine deaminase) which acts as an inhibitor of retrovirus replication and retrotransposon mobility via deaminase- dependent and -independent mechanisms. Exhibits antiviral activity against vif-deficient: HIV-1 and simian immunodeficiency viruses (SIVs) and also against simian foamy virus (SFV). After the penetration of retroviral nucleocapsids into target cells of infection and the initiation of reverse transcription, it can induce the conversion of cytosine to uracil in the minus-sense single-strand viral DNA, leading to G-to-A hy [...]	Apolipoprotein B mRNA editing enzyme catalytic subunit 2.	0.438
APOBEC3G	APOBEC3H	ENSPTRP00000024786	ENSPTRP00000083401	DNA dC->dU-editing enzyme APOBEC-3G; DNA deaminase (cytidine deaminase) which acts as an inhibitor of retrovirus replication and retrotransposon mobility via deaminase- dependent and -independent mechanisms. Exhibits antiviral activity against vif-deficient: HIV-1 and simian immunodeficiency viruses (SIVs) and also against simian foamy virus (SFV). After the penetration of retroviral nucleocapsids into target cells of infection and the initiation of reverse transcription, it can induce the conversion of cytosine to uracil in the minus-sense single-strand viral DNA, leading to G-to-A hy [...]	APOBEC3H isoform 3.	0.937
APOBEC3G	LOC470275	ENSPTRP00000024786	ENSPTRP00000090414	DNA dC->dU-editing enzyme APOBEC-3G; DNA deaminase (cytidine deaminase) which acts as an inhibitor of retrovirus replication and retrotransposon mobility via deaminase- dependent and -independent mechanisms. Exhibits antiviral activity against vif-deficient: HIV-1 and simian immunodeficiency viruses (SIVs) and also against simian foamy virus (SFV). After the penetration of retroviral nucleocapsids into target cells of infection and the initiation of reverse transcription, it can induce the conversion of cytosine to uracil in the minus-sense single-strand viral DNA, leading to G-to-A hy [...]	APOBEC3F isoform 1.	0.962
APOBEC3H	APOBEC1	ENSPTRP00000083401	ENSPTRP00000007882	APOBEC3H isoform 3.	APOBEC1 isoform 2.	0.411
APOBEC3H	APOBEC2	ENSPTRP00000083401	ENSPTRP00000050168	APOBEC3H isoform 3.	Apolipoprotein B mRNA editing enzyme catalytic subunit 2.	0.433
APOBEC3H	APOBEC3G	ENSPTRP00000083401	ENSPTRP00000024786	APOBEC3H isoform 3.	DNA dC->dU-editing enzyme APOBEC-3G; DNA deaminase (cytidine deaminase) which acts as an inhibitor of retrovirus replication and retrotransposon mobility via deaminase- dependent and -independent mechanisms. Exhibits antiviral activity against vif-deficient: HIV-1 and simian immunodeficiency viruses (SIVs) and also against simian foamy virus (SFV). After the penetration of retroviral nucleocapsids into target cells of infection and the initiation of reverse transcription, it can induce the conversion of cytosine to uracil in the minus-sense single-strand viral DNA, leading to G-to-A hy [...]	0.937
APOBEC3H	LOC470275	ENSPTRP00000083401	ENSPTRP00000090414	APOBEC3H isoform 3.	APOBEC3F isoform 1.	0.948
LOC470275	APOBEC1	ENSPTRP00000090414	ENSPTRP00000007882	APOBEC3F isoform 1.	APOBEC1 isoform 2.	0.476
LOC470275	APOBEC2	ENSPTRP00000090414	ENSPTRP00000050168	APOBEC3F isoform 1.	Apolipoprotein B mRNA editing enzyme catalytic subunit 2.	0.422
LOC470275	APOBEC3G	ENSPTRP00000090414	ENSPTRP00000024786	APOBEC3F isoform 1.	DNA dC->dU-editing enzyme APOBEC-3G; DNA deaminase (cytidine deaminase) which acts as an inhibitor of retrovirus replication and retrotransposon mobility via deaminase- dependent and -independent mechanisms. Exhibits antiviral activity against vif-deficient: HIV-1 and simian immunodeficiency viruses (SIVs) and also against simian foamy virus (SFV). After the penetration of retroviral nucleocapsids into target cells of infection and the initiation of reverse transcription, it can induce the conversion of cytosine to uracil in the minus-sense single-strand viral DNA, leading to G-to-A hy [...]	0.962
LOC470275	APOBEC3H	ENSPTRP00000090414	ENSPTRP00000083401	APOBEC3F isoform 1.	APOBEC3H isoform 3.	0.948