(4 nodes) Interferon-induced 6-16 family network (Pan troglodytes)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	IFI27L2	Interferon, alpha-inducible protein 27-like 2. (129 aa)
	IFI6-2	Interferon alpha inducible protein 6. (134 aa)
	IFI6	Interferon alpha-inducible protein 6; Plays a role in apoptosis, negatively regulating the intrinsinc apoptotic signaling pathway and TNFSF10-induced apoptosis (By similarity). However, it has also been shown to have a pro- apoptotic activity (By similarity). May have an antiviral activity (By similarity); Belongs to the IFI6/IFI27 family. (134 aa)
	IFI27	Interferon, alpha-inducible protein 27. (122 aa)

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
IFI27	IFI6	ENSPTRP00000011379	ENSPTRP00000000720	Interferon, alpha-inducible protein 27.	Interferon alpha-inducible protein 6; Plays a role in apoptosis, negatively regulating the intrinsinc apoptotic signaling pathway and TNFSF10-induced apoptosis (By similarity). However, it has also been shown to have a pro- apoptotic activity (By similarity). May have an antiviral activity (By similarity); Belongs to the IFI6/IFI27 family.	0.800
IFI27	IFI6-2	ENSPTRP00000011379	ENSPTRP00000090268	Interferon, alpha-inducible protein 27.	Interferon alpha inducible protein 6.	0.801
IFI6	IFI27	ENSPTRP00000000720	ENSPTRP00000011379	Interferon alpha-inducible protein 6; Plays a role in apoptosis, negatively regulating the intrinsinc apoptotic signaling pathway and TNFSF10-induced apoptosis (By similarity). However, it has also been shown to have a pro- apoptotic activity (By similarity). May have an antiviral activity (By similarity); Belongs to the IFI6/IFI27 family.	Interferon, alpha-inducible protein 27.	0.800
IFI6-2	IFI27	ENSPTRP00000090268	ENSPTRP00000011379	Interferon alpha inducible protein 6.	Interferon, alpha-inducible protein 27.	0.801