15 items (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	HES5-2	Hes family bHLH transcription factor 5. (165 aa)
	MAML3	MAML3 isoform 1. (1134 aa)
	SFRP5	Secreted frizzled related protein 5. (317 aa)
	MAML1	MAML1 isoform 1. (1016 aa)
	SFRP1	Secreted frizzled-related protein 1. (314 aa)
	HES5	Hes family bHLH transcription factor 5. (165 aa)
	SFRP4	SFRP4 isoform 1. (368 aa)
	SFRP2	Secreted frizzled-related protein 2. (295 aa)
	DKK3	Dickkopf WNT signaling pathway inhibitor 3. (413 aa)
	DKK2	Dickkopf WNT signaling pathway inhibitor 2. (259 aa)
	JAG1	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1218 aa)
	IHH	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (411 aa)
	WIF1	WNT inhibitory factor 1. (379 aa)
	MAML2	Mastermind like transcriptional coactivator 2. (1150 aa)
	DKK1	Dickkopf-like protein 1. (289 aa)

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DKK1	DKK2	ENSPTRP00000004327	ENSPTRP00000028083	Dickkopf-like protein 1.	Dickkopf WNT signaling pathway inhibitor 2.	0.955
DKK1	DKK3	ENSPTRP00000004327	ENSPTRP00000089459	Dickkopf-like protein 1.	Dickkopf WNT signaling pathway inhibitor 3.	0.833
DKK1	JAG1	ENSPTRP00000004327	ENSPTRP00000022729	Dickkopf-like protein 1.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.552
DKK1	SFRP1	ENSPTRP00000004327	ENSPTRP00000053182	Dickkopf-like protein 1.	Secreted frizzled-related protein 1.	0.780
DKK1	SFRP2	ENSPTRP00000004327	ENSPTRP00000028381	Dickkopf-like protein 1.	Secreted frizzled-related protein 2.	0.762
DKK1	SFRP4	ENSPTRP00000004327	ENSPTRP00000032616	Dickkopf-like protein 1.	SFRP4 isoform 1.	0.582
DKK1	SFRP5	ENSPTRP00000004327	ENSPTRP00000067322	Dickkopf-like protein 1.	Secreted frizzled related protein 5.	0.611
DKK1	WIF1	ENSPTRP00000004327	ENSPTRP00000008803	Dickkopf-like protein 1.	WNT inhibitory factor 1.	0.758
DKK2	DKK1	ENSPTRP00000028083	ENSPTRP00000004327	Dickkopf WNT signaling pathway inhibitor 2.	Dickkopf-like protein 1.	0.955
DKK2	DKK3	ENSPTRP00000028083	ENSPTRP00000089459	Dickkopf WNT signaling pathway inhibitor 2.	Dickkopf WNT signaling pathway inhibitor 3.	0.887
DKK2	IHH	ENSPTRP00000028083	ENSPTRP00000022106	Dickkopf WNT signaling pathway inhibitor 2.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.476
DKK2	MAML1	ENSPTRP00000028083	ENSPTRP00000056639	Dickkopf WNT signaling pathway inhibitor 2.	MAML1 isoform 1.	0.411
DKK2	MAML2	ENSPTRP00000028083	ENSPTRP00000007220	Dickkopf WNT signaling pathway inhibitor 2.	Mastermind like transcriptional coactivator 2.	0.412
DKK2	MAML3	ENSPTRP00000028083	ENSPTRP00000079869	Dickkopf WNT signaling pathway inhibitor 2.	MAML3 isoform 1.	0.412
DKK2	SFRP1	ENSPTRP00000028083	ENSPTRP00000053182	Dickkopf WNT signaling pathway inhibitor 2.	Secreted frizzled-related protein 1.	0.742
DKK2	SFRP2	ENSPTRP00000028083	ENSPTRP00000028381	Dickkopf WNT signaling pathway inhibitor 2.	Secreted frizzled-related protein 2.	0.700
DKK2	SFRP4	ENSPTRP00000028083	ENSPTRP00000032616	Dickkopf WNT signaling pathway inhibitor 2.	SFRP4 isoform 1.	0.637
DKK2	SFRP5	ENSPTRP00000028083	ENSPTRP00000067322	Dickkopf WNT signaling pathway inhibitor 2.	Secreted frizzled related protein 5.	0.635
DKK2	WIF1	ENSPTRP00000028083	ENSPTRP00000008803	Dickkopf WNT signaling pathway inhibitor 2.	WNT inhibitory factor 1.	0.676
DKK3	DKK1	ENSPTRP00000089459	ENSPTRP00000004327	Dickkopf WNT signaling pathway inhibitor 3.	Dickkopf-like protein 1.	0.833