17 items (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	DLX3	Distal-less homeobox 3. (287 aa)
	SOX9	Transcription factor SOX-9; Transcriptional regulator that plays a role in chondrocytes differentiation and skeletal development. Binds to the COL2A1 promoter and activates COL2A1 expression, as part of a complex with ZNF219. (509 aa)
	DLX2	Distal-less homeobox 2. (328 aa)
	EVX2	Even-skipped homeobox 2. (476 aa)
	HOXD13	HOXD13 isoform 1. (344 aa)
	HOXD10	Homeobox protein Hox-D10; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis; Belongs to the Abd-B homeobox family. (410 aa)
	ISL1	ISL LIM homeobox 1. (349 aa)
	LMBR1	LMBR1 isoform 7; Belongs to the LIMR family. (531 aa)
	ELP4	ELP4 isoform 9. (534 aa)
	GATA2	GATA binding protein 2. (480 aa)
	DLX6	DLX6 isoform 1. (295 aa)
	POU3F4	POU domain protein. (361 aa)
	MAF	MAF isoform 2; Belongs to the bZIP family. (402 aa)
	FGF8	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (244 aa)
	TEAD2	TEA domain transcription factor 2. (451 aa)
	PAX3	PAX3 isoform 4. (505 aa)
	OTX2	Orthodenticle homeobox 2. (297 aa)

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DLX2	FGF8	ENSPTRP00000021601	ENSPTRP00000075677	Distal-less homeobox 2.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.559
DLX2	SOX9	ENSPTRP00000021601	ENSPTRP00000016293	Distal-less homeobox 2.	Transcription factor SOX-9; Transcriptional regulator that plays a role in chondrocytes differentiation and skeletal development. Binds to the COL2A1 promoter and activates COL2A1 expression, as part of a complex with ZNF219.	0.475
EVX2	HOXD10	ENSPTRP00000021642	ENSPTRP00000021646	Even-skipped homeobox 2.	Homeobox protein Hox-D10; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis; Belongs to the Abd-B homeobox family.	0.556
EVX2	HOXD13	ENSPTRP00000021642	ENSPTRP00000021643	Even-skipped homeobox 2.	HOXD13 isoform 1.	0.415
FGF8	DLX2	ENSPTRP00000075677	ENSPTRP00000021601	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Distal-less homeobox 2.	0.559
FGF8	HOXD13	ENSPTRP00000075677	ENSPTRP00000021643	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	HOXD13 isoform 1.	0.454
FGF8	ISL1	ENSPTRP00000075677	ENSPTRP00000028882	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	ISL LIM homeobox 1.	0.489
FGF8	OTX2	ENSPTRP00000075677	ENSPTRP00000010823	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Orthodenticle homeobox 2.	0.647
FGF8	SOX9	ENSPTRP00000075677	ENSPTRP00000016293	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Transcription factor SOX-9; Transcriptional regulator that plays a role in chondrocytes differentiation and skeletal development. Binds to the COL2A1 promoter and activates COL2A1 expression, as part of a complex with ZNF219.	0.484
GATA2	ISL1	ENSPTRP00000054198	ENSPTRP00000028882	GATA binding protein 2.	ISL LIM homeobox 1.	0.470
HOXD10	EVX2	ENSPTRP00000021646	ENSPTRP00000021642	Homeobox protein Hox-D10; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis; Belongs to the Abd-B homeobox family.	Even-skipped homeobox 2.	0.556
HOXD10	HOXD13	ENSPTRP00000021646	ENSPTRP00000021643	Homeobox protein Hox-D10; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis; Belongs to the Abd-B homeobox family.	HOXD13 isoform 1.	0.667
HOXD13	EVX2	ENSPTRP00000021643	ENSPTRP00000021642	HOXD13 isoform 1.	Even-skipped homeobox 2.	0.415
HOXD13	FGF8	ENSPTRP00000021643	ENSPTRP00000075677	HOXD13 isoform 1.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.454
HOXD13	HOXD10	ENSPTRP00000021643	ENSPTRP00000021646	HOXD13 isoform 1.	Homeobox protein Hox-D10; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis; Belongs to the Abd-B homeobox family.	0.667
ISL1	FGF8	ENSPTRP00000028882	ENSPTRP00000075677	ISL LIM homeobox 1.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.489
ISL1	GATA2	ENSPTRP00000028882	ENSPTRP00000054198	ISL LIM homeobox 1.	GATA binding protein 2.	0.470
ISL1	OTX2	ENSPTRP00000028882	ENSPTRP00000010823	ISL LIM homeobox 1.	Orthodenticle homeobox 2.	0.511
ISL1	PAX3	ENSPTRP00000028882	ENSPTRP00000090733	ISL LIM homeobox 1.	PAX3 isoform 4.	0.436
MAF	SOX9	ENSPTRP00000075211	ENSPTRP00000016293	MAF isoform 2; Belongs to the bZIP family.	Transcription factor SOX-9; Transcriptional regulator that plays a role in chondrocytes differentiation and skeletal development. Binds to the COL2A1 promoter and activates COL2A1 expression, as part of a complex with ZNF219.	0.430