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DCUN1D1 | DCN1-like protein. (259 aa) | ||||
DCUN1D4 | DCN1-like protein. (336 aa) | ||||
EGF | Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1207 aa) | ||||
EXOC2 | Exocyst complex component 2; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. Belongs to the SEC5 family. (924 aa) | ||||
MAPK14 | Mitogen-activated protein kinase 14; Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK14 is one of the four p38 MAPKs which play an important role in the cascades of cellular responses evoked by extracellular stimuli such as proinflammatory cytokines or physical stress leading to direct activation of transcription factors. Accordingly, p38 MAPKs phosphorylate a broad range of proteins and it has been estimated that they may have approximately 200 to 300 substrates each. Some of the targets are downstream kinases which are a [...] (360 aa) | ||||
DLL1 | Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (723 aa) | ||||
EPHB4 | EPH receptor B4. (987 aa) | ||||
SDAD1 | Protein SDA1; Required for 60S pre-ribosomal subunits export to the cytoplasm; Belongs to the SDA1 family. (687 aa) | ||||
AXIN1 | AXIN1 isoform 2. (859 aa) | ||||
SOS2 | SOS Ras/Rho guanine nucleotide exchange factor 2. (1332 aa) | ||||
DCUN1D3 | DCN1-like protein. (304 aa) | ||||
STAT1 | Signal transducer and activator of transcription. (758 aa) | ||||
EFNB1 | EFNB1 isoform 1; Belongs to the ephrin family. (346 aa) | ||||
WNT5A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa) | ||||
ARAF | V-raf murine sarcoma 3611 viral oncogene homolog. (606 aa) | ||||
MET | Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...] (1413 aa) | ||||
AKT1 | AKT1 isoform 3; Belongs to the protein kinase superfamily. (480 aa) | ||||
FBF1 | T0139750 isoform 2. (1181 aa) | ||||
TIAM2 | T cell lymphoma invasion and metastasis 2. (1730 aa) | ||||
LEF1 | Lymphoid enhancer binding factor 1. (414 aa) | ||||
EPHB4-2 | EPH receptor B4. (987 aa) | ||||
SRC | Tyrosine-protein kinase. (542 aa) | ||||
EGFR | Receptor protein-tyrosine kinase. (1210 aa) | ||||
RHOB | Ras homolog gene family, member B. (286 aa) | ||||
FGFR1 | Fibroblast growth factor receptor. (854 aa) | ||||
MAPKAPK5 | Mitogen-activated protein kinase-activated protein kinase 5. (487 aa) | ||||
DLL3 | Delta like canonical Notch ligand 3. (618 aa) | ||||
ATF2 | Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa) | ||||
ACTB | Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. (378 aa) | ||||
ALB | ALB isoform 2. (609 aa) | ||||
SOS1 | SOS Ras/Rac guanine nucleotide exchange factor 1. (1333 aa) | ||||
SHC1 | SHC (Src homology 2 domain containing) transforming protein 1. (584 aa) | ||||
MAP3K1 | MAP3K1 isoform 1. (1509 aa) | ||||
RABIF | RAB interacting factor. (123 aa) | ||||
MMP1 | Matrix metallopeptidase 1 (Interstitial collagenase). (469 aa) | ||||
RPS26 | 40S ribosomal protein S26; Belongs to the eukaryotic ribosomal protein eS26 family. (115 aa) | ||||
RHOF | Ras homolog family member F, filopodia associated. (211 aa) | ||||
FLT1 | Fms related tyrosine kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1338 aa) | ||||
SLC7A1 | Solute carrier family 7 (Cationic amino acid transporter, y+ system), member 1. (629 aa) | ||||
RHOJ | Ras homolog gene family, member J. (214 aa) | ||||
COX10 | Protoheme IX farnesyltransferase, mitochondrial; Converts protoheme IX and farnesyl diphosphate to heme O. Belongs to the ubiA prenyltransferase family. (432 aa) | ||||
GRB2 | Growth factor receptor-bound protein 2. (217 aa) | ||||
GSK3A | Glycogen synthase kinase 3 alpha. (483 aa) | ||||
MAPK1 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa) | ||||
PIK3CB | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1084 aa) |