node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AFP | ALB | ENSPTRP00000027765 | ENSPTRP00000056218 | Alpha-fetoprotein; Binds copper, nickel, and fatty acids as well as, and bilirubin less well than, serum albumin; Belongs to the ALB/AFP/VDB family. | ALB isoform 2. | 0.784 |
AFP | CD4 | ENSPTRP00000027765 | ENSPTRP00000054833 | Alpha-fetoprotein; Binds copper, nickel, and fatty acids as well as, and bilirubin less well than, serum albumin; Belongs to the ALB/AFP/VDB family. | T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...] | 0.510 |
AFP | FOXA1 | ENSPTRP00000027765 | ENSPTRP00000062658 | Alpha-fetoprotein; Binds copper, nickel, and fatty acids as well as, and bilirubin less well than, serum albumin; Belongs to the ALB/AFP/VDB family. | FOXA1 isoform 1. | 0.468 |
AFP | FOXA2 | ENSPTRP00000027765 | ENSPTRP00000090114 | Alpha-fetoprotein; Binds copper, nickel, and fatty acids as well as, and bilirubin less well than, serum albumin; Belongs to the ALB/AFP/VDB family. | FOXA2 isoform 1. | 0.591 |
AFP | FOXA3 | ENSPTRP00000027765 | ENSPTRP00000019177 | Alpha-fetoprotein; Binds copper, nickel, and fatty acids as well as, and bilirubin less well than, serum albumin; Belongs to the ALB/AFP/VDB family. | FOXA3 isoform 2. | 0.518 |
AFP | INS | ENSPTRP00000027765 | ENSPTRP00000077843 | Alpha-fetoprotein; Binds copper, nickel, and fatty acids as well as, and bilirubin less well than, serum albumin; Belongs to the ALB/AFP/VDB family. | Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. | 0.493 |
AFP | TTR | ENSPTRP00000027765 | ENSPTRP00000081072 | Alpha-fetoprotein; Binds copper, nickel, and fatty acids as well as, and bilirubin less well than, serum albumin; Belongs to the ALB/AFP/VDB family. | Transthyretin; Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain (By similarity). Belongs to the transthyretin family. | 0.738 |
ALB | AFP | ENSPTRP00000056218 | ENSPTRP00000027765 | ALB isoform 2. | Alpha-fetoprotein; Binds copper, nickel, and fatty acids as well as, and bilirubin less well than, serum albumin; Belongs to the ALB/AFP/VDB family. | 0.784 |
ALB | CD4 | ENSPTRP00000056218 | ENSPTRP00000054833 | ALB isoform 2. | T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...] | 0.774 |
ALB | FGF2 | ENSPTRP00000056218 | ENSPTRP00000067812 | ALB isoform 2. | Fibroblast growth factor 2; Acts as a ligand for FGFR1, FGFR2, FGFR3 and FGFR4. Also acts as an integrin ligand which is required for FGF2 signaling. Binds to integrin ITGAV:ITGB3. Plays an important role in the regulation of cell survival, cell division, cell differentiation and cell migration. Functions as a potent mitogen in vitro. Can induce angiogenesis. | 0.693 |
ALB | FOXA1 | ENSPTRP00000056218 | ENSPTRP00000062658 | ALB isoform 2. | FOXA1 isoform 1. | 0.472 |
ALB | FOXA2 | ENSPTRP00000056218 | ENSPTRP00000090114 | ALB isoform 2. | FOXA2 isoform 1. | 0.565 |
ALB | FOXA3 | ENSPTRP00000056218 | ENSPTRP00000019177 | ALB isoform 2. | FOXA3 isoform 2. | 0.488 |
ALB | FOXP3 | ENSPTRP00000056218 | ENSPTRP00000037587 | ALB isoform 2. | FOXP3 isoform 4. | 0.504 |
ALB | IGF1 | ENSPTRP00000056218 | ENSPTRP00000067917 | ALB isoform 2. | Insulin-like growth factor 1 (Somatomedin C). | 0.677 |
ALB | INS | ENSPTRP00000056218 | ENSPTRP00000077843 | ALB isoform 2. | Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. | 0.799 |
ALB | TTR | ENSPTRP00000056218 | ENSPTRP00000081072 | ALB isoform 2. | Transthyretin; Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain (By similarity). Belongs to the transthyretin family. | 0.899 |
CD4 | AFP | ENSPTRP00000054833 | ENSPTRP00000027765 | T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...] | Alpha-fetoprotein; Binds copper, nickel, and fatty acids as well as, and bilirubin less well than, serum albumin; Belongs to the ALB/AFP/VDB family. | 0.510 |
CD4 | ALB | ENSPTRP00000054833 | ENSPTRP00000056218 | T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...] | ALB isoform 2. | 0.774 |
CD4 | FOXN1 | ENSPTRP00000054833 | ENSPTRP00000015225 | T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...] | FOXN1 isoform 2. | 0.409 |