STRINGSTRING
GLUL GLUL SLC1A7 SLC1A7 SLC1A6 SLC1A6 SLIT1 SLIT1 SLC1A3 SLC1A3 SLC1A5 SLC1A5 TNF TNF OLIG2 OLIG2 BEST1 BEST1 SLC1A2 SLC1A2 PAX6 PAX6 RELN RELN SLC1A1 SLC1A1 DLX2 DLX2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GLULGlutamine synthetase. (373 aa)
SLC1A7Amino acid transporter. (619 aa)
SLC1A6Amino acid transporter. (564 aa)
SLIT1Slit guidance ligand 1. (1534 aa)
SLC1A3Amino acid transporter. (542 aa)
SLC1A5Amino acid transporter. (541 aa)
TNFTumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] (234 aa)
OLIG2OLIG2 isoform 1. (323 aa)
BEST1Bestrophin; Forms calcium-sensitive chloride channels. Permeable to bicarbonate; Belongs to the bestrophin family. (664 aa)
SLC1A2Amino acid transporter. (574 aa)
PAX6PAX6 isoform 13. (436 aa)
RELNRELN isoform 3. (3460 aa)
SLC1A1Amino acid transporter. (524 aa)
DLX2Distal-less homeobox 2. (328 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.