Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CD4 | CD8B | ENSPTRP00000054833 | ENSPTRP00000059042 | T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...] | CD8B isoform 3. | 0.961 |
| CD4 | GAPDH | ENSPTRP00000054833 | ENSPTRP00000007822 | T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...] | Glyceraldehyde-3-phosphate dehydrogenase. | 0.661 |
| CD4 | GRB2 | ENSPTRP00000054833 | ENSPTRP00000016382 | T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...] | Growth factor receptor-bound protein 2. | 0.410 |
| CD4 | IFNG | ENSPTRP00000054833 | ENSPTRP00000008822 | T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...] | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons (By similarity). | 0.929 |
| CD4 | IL2 | ENSPTRP00000054833 | ENSPTRP00000028193 | T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...] | Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family. | 0.933 |
| CD4 | SRC | ENSPTRP00000054833 | ENSPTRP00000076797 | T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...] | Tyrosine-protein kinase. | 0.635 |
| CD4 | ZAP70 | ENSPTRP00000054833 | ENSPTRP00000021008 | T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...] | Tyrosine-protein kinase. | 0.966 |
| CD8B | CD4 | ENSPTRP00000059042 | ENSPTRP00000054833 | CD8B isoform 3. | T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...] | 0.961 |
| CD8B | ZAP70 | ENSPTRP00000059042 | ENSPTRP00000021008 | CD8B isoform 3. | Tyrosine-protein kinase. | 0.939 |
| EPS15 | GRB2 | ENSPTRP00000001250 | ENSPTRP00000016382 | Epidermal growth factor receptor pathway substrate 15. | Growth factor receptor-bound protein 2. | 0.766 |
| EPS15 | UBD | ENSPTRP00000001250 | ENSPTRP00000030511 | Epidermal growth factor receptor pathway substrate 15. | UBD isoform 1. | 0.652 |
| EPS15 | ZAP70 | ENSPTRP00000001250 | ENSPTRP00000021008 | Epidermal growth factor receptor pathway substrate 15. | Tyrosine-protein kinase. | 0.647 |
| GAPDH | CD4 | ENSPTRP00000007822 | ENSPTRP00000054833 | Glyceraldehyde-3-phosphate dehydrogenase. | T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...] | 0.661 |
| GAPDH | IFNG | ENSPTRP00000007822 | ENSPTRP00000008822 | Glyceraldehyde-3-phosphate dehydrogenase. | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons (By similarity). | 0.669 |
| GAPDH | IL2 | ENSPTRP00000007822 | ENSPTRP00000028193 | Glyceraldehyde-3-phosphate dehydrogenase. | Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family. | 0.663 |
| GAPDH | SRC | ENSPTRP00000007822 | ENSPTRP00000076797 | Glyceraldehyde-3-phosphate dehydrogenase. | Tyrosine-protein kinase. | 0.547 |
| GRB2 | CD4 | ENSPTRP00000016382 | ENSPTRP00000054833 | Growth factor receptor-bound protein 2. | T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...] | 0.410 |
| GRB2 | EPS15 | ENSPTRP00000016382 | ENSPTRP00000001250 | Growth factor receptor-bound protein 2. | Epidermal growth factor receptor pathway substrate 15. | 0.766 |
| GRB2 | IL2 | ENSPTRP00000016382 | ENSPTRP00000028193 | Growth factor receptor-bound protein 2. | Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family. | 0.411 |
| GRB2 | SOS1 | ENSPTRP00000016382 | ENSPTRP00000052023 | Growth factor receptor-bound protein 2. | SOS Ras/Rac guanine nucleotide exchange factor 1. | 0.999 |
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