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INSR | Tyrosine-protein kinase receptor. (1408 aa) | ||||
CRK | V-crk sarcoma virus CT10 oncogene homolog (Avian). (304 aa) | ||||
GRB2 | Growth factor receptor-bound protein 2. (217 aa) | ||||
INS | Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (200 aa) | ||||
FYN | Tyrosine-protein kinase. (537 aa) | ||||
SRC | Tyrosine-protein kinase. (542 aa) | ||||
IGF1 | Insulin-like growth factor 1 (Somatomedin C). (196 aa) | ||||
BRCA1 | Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] (1884 aa) | ||||
CDX2 | Caudal type homeobox 2. (313 aa) | ||||
BRCA2 | Breast cancer 2, early onset. (3418 aa) | ||||
IRS2 | IRS2 isoform 1. (1340 aa) | ||||
IRS4 | Insulin receptor substrate 4. (1257 aa) |