STRINGSTRING
YY1 YY1 SOX5 SOX5 NPAS4 NPAS4 EMX2 EMX2 USF1 USF1 STAT3 STAT3 NR2E1-2 NR2E1-2 SOX11 SOX11 CUX1 CUX1 TAF1 TAF1 CUX2 CUX2 NR2F1 NR2F1 LHX6 LHX6 CHIA CHIA FEZF1 FEZF1 HES5-2 HES5-2 SATB2 SATB2 OLIG1-2 OLIG1-2 FEZF2 FEZF2 NR2F2 NR2F2 FOS FOS ASCL1 ASCL1 PVALB PVALB POU3F3 POU3F3 CREBBP CREBBP CNTN4 CNTN4 ARNT2 ARNT2 SMARCA4 SMARCA4 NR2E1 NR2E1 DOT1L DOT1L CALB2 CALB2 ID4 ID4 OLIG2 OLIG2 RND2 RND2 SST SST PAX6 PAX6 OLIG1 OLIG1 BDNF BDNF EMX1 EMX1 RELN RELN FOXG1 FOXG1 BCL11B BCL11B NFIA NFIA SOX4 SOX4 TBR1 TBR1 SOX6 SOX6 SOX10 SOX10 HES5 HES5 LHX2 LHX2 NPY NPY RHOA RHOA EP300 EP300 TFAP2C TFAP2C DLX2 DLX2 DPP10 DPP10 SUZ12 SUZ12 CTCF CTCF
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
YY1YY1 transcription factor. (414 aa)
SOX5SRY (Sex determining region Y)-box 5. (765 aa)
NPAS4Neuronal PAS domain protein 4. (802 aa)
EMX2Empty spiracles homeobox 2. (252 aa)
USF1Upstream transcription factor 1. (310 aa)
STAT3Signal transducer and activator of transcription. (790 aa)
NR2E1-2Nuclear receptor subfamily 2 group E member 1. (385 aa)
SOX11Transcription factor SOX. (441 aa)
CUX1Homeobox protein cut-like. (1515 aa)
TAF1Transcription initiation factor TFIID subunit. (1927 aa)
CUX2Homeobox protein cut-like. (1489 aa)
NR2F1Nuclear receptor subfamily 2 group F member 1. (423 aa)
LHX6LHX6 isoform 3. (428 aa)
CHIACHIA isoform 3; Belongs to the glycosyl hydrolase 18 family. (466 aa)
FEZF1FEZ family zinc finger 1. (475 aa)
HES5-2Hes family bHLH transcription factor 5. (165 aa)
SATB2DNA-binding protein SATB. (733 aa)
OLIG1-2OLIG1 isoform 1. (272 aa)
FEZF2FEZ family zinc finger 2. (463 aa)
NR2F2Nuclear receptor subfamily 2, group F, member 2. (414 aa)
FOSFos proto-oncogene, AP-1 transcription factor subunit. (380 aa)
ASCL1Achaete-scute family bHLH transcription factor 1. (232 aa)
PVALBPVALB isoform 1; Belongs to the parvalbumin family. (110 aa)
POU3F3POU domain protein. (476 aa)
CREBBPCREB binding protein. (2442 aa)
CNTN4CNTN4 isoform 10. (1027 aa)
ARNT2ARNT2 isoform 2. (759 aa)
SMARCA4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4. (1679 aa)
NR2E1Nuclear receptor subfamily 2 group E member 1. (422 aa)
DOT1LHistone-lysine N-methyltransferase, H3 lysine-79 specific. (1562 aa)
CALB2CALB2 isoform 1. (271 aa)
ID4Inhibitor of DNA binding 4, dominant negative helix-loop-helix protein. (161 aa)
OLIG2OLIG2 isoform 1. (323 aa)
RND2Rho family GTPase 2. (227 aa)
SSTSST isoform 1. (116 aa)
PAX6PAX6 isoform 13. (436 aa)
OLIG1OLIG1 isoform 2. (272 aa)
BDNFBrain-derived neurotrophic factor; Important signaling molecule that activates signaling cascades downstream of NTRK2 (By similarity). During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including lo [...] (329 aa)
EMX1Empty spiracles homeobox 1. (290 aa)
RELNRELN isoform 3. (3460 aa)
FOXG1FOXG1 isoform 8. (489 aa)
BCL11BBAF chromatin remodeling complex subunit BCL11B. (894 aa)
NFIANuclear factor 1; Recognizes and binds the palindromic sequence 5'- TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication. (554 aa)
SOX4Transcription factor SOX. (474 aa)
TBR1T-box brain transcription factor 1. (682 aa)
SOX6SOX6 isoform 9. (828 aa)
SOX10SRY-box transcription factor 10. (466 aa)
HES5Hes family bHLH transcription factor 5. (165 aa)
LHX2LHX2 isoform 1. (406 aa)
NPYNeuropeptide Y. (97 aa)
RHOARas homolog family member A. (193 aa)
EP300E1A binding protein p300. (2175 aa)
TFAP2CTranscription factor AP-2 gamma. (450 aa)
DLX2Distal-less homeobox 2. (328 aa)
DPP10DPP10 isoform 3; Belongs to the peptidase S9B family. (881 aa)
SUZ12SUZ12 polycomb repressive complex 2 subunit. (739 aa)
CTCFCCCTC-binding factor (Zinc finger protein). (727 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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