23 items (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	HES5-2	Hes family bHLH transcription factor 5. (165 aa)
	EFNB2	EFNB2 isoform 1; Belongs to the ephrin family. (333 aa)
	BMP4	Bone morphogenetic protein 4. (408 aa)
	ID2	Inhibitor of DNA binding 2, dominant negative helix-loop-helix protein. (134 aa)
	JAG1	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1218 aa)
	EGF	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1207 aa)
	HEY2	Hairy/enhancer-of-split related with YRPW motif 2. (337 aa)
	DLL1	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (723 aa)
	PXDNL	PXDNL isoform 2. (1463 aa)
	VCP	Valosin containing protein; Belongs to the AAA ATPase family. (806 aa)
	HES5	Hes family bHLH transcription factor 5. (165 aa)
	RPS29	RPS29 isoform 2. (106 aa)
	MAML1	MAML1 isoform 1. (1016 aa)
	NOTCH4	NOTCH4 isoform 3. (2006 aa)
	DLL3	Delta like canonical Notch ligand 3. (618 aa)
	CCL2	C-C motif chemokine. (109 aa)
	HEY1	Hes related family bHLH transcription factor with YRPW motif 1. (304 aa)
	DLL4	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (696 aa)
	JAG2	Jagged canonical Notch ligand 2. (1130 aa)
	BMP10	Bone morphogenetic protein 10. (424 aa)
	BMP4-2	Bone morphogenetic protein 4. (408 aa)
	HEYL	Hes related family bHLH transcription factor with YRPW motif like. (328 aa)
	PXDN	Peroxidasin homolog. (1479 aa)

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BMP10	BMP4	ENSPTRP00000078228	ENSPTRP00000010780	Bone morphogenetic protein 10.	Bone morphogenetic protein 4.	0.505
BMP10	BMP4-2	ENSPTRP00000078228	ENSPTRP00000080656	Bone morphogenetic protein 10.	Bone morphogenetic protein 4.	0.505
BMP4	BMP10	ENSPTRP00000010780	ENSPTRP00000078228	Bone morphogenetic protein 4.	Bone morphogenetic protein 10.	0.505
BMP4	EGF	ENSPTRP00000010780	ENSPTRP00000028112	Bone morphogenetic protein 4.	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	0.495
BMP4-2	BMP10	ENSPTRP00000080656	ENSPTRP00000078228	Bone morphogenetic protein 4.	Bone morphogenetic protein 10.	0.505
BMP4-2	EGF	ENSPTRP00000080656	ENSPTRP00000028112	Bone morphogenetic protein 4.	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	0.495
CCL2	EGF	ENSPTRP00000068745	ENSPTRP00000028112	C-C motif chemokine.	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	0.545
CCL2	PXDN	ENSPTRP00000068745	ENSPTRP00000090912	C-C motif chemokine.	Peroxidasin homolog.	0.469
CCL2	PXDNL	ENSPTRP00000068745	ENSPTRP00000034664	C-C motif chemokine.	PXDNL isoform 2.	0.469
DLL1	DLL3	ENSPTRP00000032142	ENSPTRP00000063771	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Delta like canonical Notch ligand 3.	0.929
DLL1	DLL4	ENSPTRP00000032142	ENSPTRP00000070341	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.552
DLL1	EFNB2	ENSPTRP00000032142	ENSPTRP00000010233	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	EFNB2 isoform 1; Belongs to the ephrin family.	0.467
DLL1	EGF	ENSPTRP00000032142	ENSPTRP00000028112	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	0.463
DLL1	HES5	ENSPTRP00000032142	ENSPTRP00000040760	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Hes family bHLH transcription factor 5.	0.712
DLL1	HES5-2	ENSPTRP00000032142	ENSPTRP00000080637	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Hes family bHLH transcription factor 5.	0.712
DLL1	HEY1	ENSPTRP00000032142	ENSPTRP00000069126	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Hes related family bHLH transcription factor with YRPW motif 1.	0.737
DLL1	HEY2	ENSPTRP00000032142	ENSPTRP00000031710	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Hairy/enhancer-of-split related with YRPW motif 2.	0.573
DLL1	HEYL	ENSPTRP00000032142	ENSPTRP00000089331	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Hes related family bHLH transcription factor with YRPW motif like.	0.524
DLL1	JAG1	ENSPTRP00000032142	ENSPTRP00000022729	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.712
DLL1	JAG2	ENSPTRP00000032142	ENSPTRP00000075993	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Jagged canonical Notch ligand 2.	0.484