15 items (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	TGFB3	Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
	TGFB2	Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
	FGF4	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (206 aa)
	BMP4	Bone morphogenetic protein 4. (408 aa)
	KLF2	Kruppel-like factor 2 (Lung). (355 aa)
	TGFB1	Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
	SOX17	SOX17 isoform 1. (416 aa)
	WWP1	E3 ubiquitin-protein ligase. (922 aa)
	KLF4	Kruppel-like factor 4 (Gut). (479 aa)
	PPARD	Peroxisome proliferator-activated receptor delta. (441 aa)
	ACTB	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. (378 aa)
	PAX6	PAX6 isoform 13. (436 aa)
	CDX2	Caudal type homeobox 2. (313 aa)
	CREBBP	CREB binding protein. (2442 aa)
	BMP4-2	Bone morphogenetic protein 4. (408 aa)

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACTB	CREBBP	ENSPTRP00000058292	ENSPTRP00000074980	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.	CREB binding protein.	0.430
ACTB	KLF4	ENSPTRP00000058292	ENSPTRP00000036269	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.	Kruppel-like factor 4 (Gut).	0.469
ACTB	TGFB1	ENSPTRP00000058292	ENSPTRP00000018930	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.508
BMP4	CDX2	ENSPTRP00000010780	ENSPTRP00000070197	Bone morphogenetic protein 4.	Caudal type homeobox 2.	0.453
BMP4	FGF4	ENSPTRP00000010780	ENSPTRP00000006879	Bone morphogenetic protein 4.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.640
BMP4	KLF4	ENSPTRP00000010780	ENSPTRP00000036269	Bone morphogenetic protein 4.	Kruppel-like factor 4 (Gut).	0.478
BMP4	PAX6	ENSPTRP00000010780	ENSPTRP00000065705	Bone morphogenetic protein 4.	PAX6 isoform 13.	0.475
BMP4	SOX17	ENSPTRP00000010780	ENSPTRP00000034688	Bone morphogenetic protein 4.	SOX17 isoform 1.	0.523
BMP4-2	CDX2	ENSPTRP00000080656	ENSPTRP00000070197	Bone morphogenetic protein 4.	Caudal type homeobox 2.	0.453
BMP4-2	FGF4	ENSPTRP00000080656	ENSPTRP00000006879	Bone morphogenetic protein 4.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.640
BMP4-2	KLF4	ENSPTRP00000080656	ENSPTRP00000036269	Bone morphogenetic protein 4.	Kruppel-like factor 4 (Gut).	0.478
BMP4-2	PAX6	ENSPTRP00000080656	ENSPTRP00000065705	Bone morphogenetic protein 4.	PAX6 isoform 13.	0.475
BMP4-2	SOX17	ENSPTRP00000080656	ENSPTRP00000034688	Bone morphogenetic protein 4.	SOX17 isoform 1.	0.523
CDX2	BMP4	ENSPTRP00000070197	ENSPTRP00000010780	Caudal type homeobox 2.	Bone morphogenetic protein 4.	0.453
CDX2	BMP4-2	ENSPTRP00000070197	ENSPTRP00000080656	Caudal type homeobox 2.	Bone morphogenetic protein 4.	0.453
CDX2	FGF4	ENSPTRP00000070197	ENSPTRP00000006879	Caudal type homeobox 2.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.473
CDX2	KLF4	ENSPTRP00000070197	ENSPTRP00000036269	Caudal type homeobox 2.	Kruppel-like factor 4 (Gut).	0.491
CDX2	PAX6	ENSPTRP00000070197	ENSPTRP00000065705	Caudal type homeobox 2.	PAX6 isoform 13.	0.427
CDX2	SOX17	ENSPTRP00000070197	ENSPTRP00000034688	Caudal type homeobox 2.	SOX17 isoform 1.	0.558
CREBBP	ACTB	ENSPTRP00000074980	ENSPTRP00000058292	CREB binding protein.	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.	0.430