18 items (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	HAMP	Hepcidin antimicrobial peptide. (84 aa)
	CYBRD1	Cytochrome b reductase 1. (286 aa)
	SLC40A1	Solute carrier family 40 protein; May be involved in iron transport and iron homeostasis. Belongs to the ferroportin (FP) (TC 2.A.100) family. SLC40A subfamily. (571 aa)
	GFI1	Growth factor independent 1 transcriptional repressor. (422 aa)
	GNPAT	Dihydroxyacetone phosphate acyltransferase. (691 aa)
	HLA-A	Patr class I histocompatibility antigen, A-108 alpha chain; Involved in the presentation of foreign antigens to the immune system. (365 aa)
	GATA1	GATA binding protein 1. (413 aa)
	HJV	HFE2 isoform 1. (426 aa)
	EPO-2	Erythropoietin. (193 aa)
	ENSPTRP00000078404	annotation not available (801 aa)
	LCN2	Lipocalin 2. (240 aa)
	ARNTL	Aryl hydrocarbon receptor nuclear translocator-like. (628 aa)
	LCN2-2	LCN2 isoform 5; Belongs to the calycin superfamily. Lipocalin family. (200 aa)
	TFRC	Transferrin receptor (P90, CD71). (760 aa)
	EPO	Erythropoietin; Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3. Belongs to the EPO/TPO family. (193 aa)
	TFR2	Transferrin receptor 2. (801 aa)
	UROD	Uroporphyrinogen decarboxylase; Belongs to the uroporphyrinogen decarboxylase family. (367 aa)
	PARP1	Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1014 aa)

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARNTL	CYBRD1	ENSPTRP00000066426	ENSPTRP00000021592	Aryl hydrocarbon receptor nuclear translocator-like.	Cytochrome b reductase 1.	0.434
ARNTL	GNPAT	ENSPTRP00000066426	ENSPTRP00000093925	Aryl hydrocarbon receptor nuclear translocator-like.	Dihydroxyacetone phosphate acyltransferase.	0.426
CYBRD1	ARNTL	ENSPTRP00000021592	ENSPTRP00000066426	Cytochrome b reductase 1.	Aryl hydrocarbon receptor nuclear translocator-like.	0.434
CYBRD1	ENSPTRP00000078404	ENSPTRP00000021592	ENSPTRP00000078404	Cytochrome b reductase 1.	annotation not available	0.702
CYBRD1	GNPAT	ENSPTRP00000021592	ENSPTRP00000093925	Cytochrome b reductase 1.	Dihydroxyacetone phosphate acyltransferase.	0.640
CYBRD1	HAMP	ENSPTRP00000021592	ENSPTRP00000018553	Cytochrome b reductase 1.	Hepcidin antimicrobial peptide.	0.690
CYBRD1	HJV	ENSPTRP00000021592	ENSPTRP00000085910	Cytochrome b reductase 1.	HFE2 isoform 1.	0.575
CYBRD1	SLC40A1	ENSPTRP00000021592	ENSPTRP00000021763	Cytochrome b reductase 1.	Solute carrier family 40 protein; May be involved in iron transport and iron homeostasis. Belongs to the ferroportin (FP) (TC 2.A.100) family. SLC40A subfamily.	0.745
CYBRD1	TFR2	ENSPTRP00000021592	ENSPTRP00000033379	Cytochrome b reductase 1.	Transferrin receptor 2.	0.663
CYBRD1	TFRC	ENSPTRP00000021592	ENSPTRP00000046807	Cytochrome b reductase 1.	Transferrin receptor (P90, CD71).	0.667
ENSPTRP00000078404	CYBRD1	ENSPTRP00000078404	ENSPTRP00000021592	annotation not available	Cytochrome b reductase 1.	0.702
ENSPTRP00000078404	GNPAT	ENSPTRP00000078404	ENSPTRP00000093925	annotation not available	Dihydroxyacetone phosphate acyltransferase.	0.541
ENSPTRP00000078404	HAMP	ENSPTRP00000078404	ENSPTRP00000018553	annotation not available	Hepcidin antimicrobial peptide.	0.783
ENSPTRP00000078404	HJV	ENSPTRP00000078404	ENSPTRP00000085910	annotation not available	HFE2 isoform 1.	0.720
ENSPTRP00000078404	SLC40A1	ENSPTRP00000078404	ENSPTRP00000021763	annotation not available	Solute carrier family 40 protein; May be involved in iron transport and iron homeostasis. Belongs to the ferroportin (FP) (TC 2.A.100) family. SLC40A subfamily.	0.814
ENSPTRP00000078404	TFRC	ENSPTRP00000078404	ENSPTRP00000046807	annotation not available	Transferrin receptor (P90, CD71).	0.516
GATA1	GFI1	ENSPTRP00000086593	ENSPTRP00000093933	GATA binding protein 1.	Growth factor independent 1 transcriptional repressor.	0.746
GATA1	TFRC	ENSPTRP00000086593	ENSPTRP00000046807	GATA binding protein 1.	Transferrin receptor (P90, CD71).	0.476
GFI1	GATA1	ENSPTRP00000093933	ENSPTRP00000086593	Growth factor independent 1 transcriptional repressor.	GATA binding protein 1.	0.746
GNPAT	ARNTL	ENSPTRP00000093925	ENSPTRP00000066426	Dihydroxyacetone phosphate acyltransferase.	Aryl hydrocarbon receptor nuclear translocator-like.	0.426