26 items (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	GPT2	Glutamic pyruvate transaminase (Alanine aminotransferase) 2. (523 aa)
	GAPDH	Glyceraldehyde-3-phosphate dehydrogenase. (335 aa)
	HPX	Hemopexin; Binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation. (462 aa)
	HMGCS2	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (508 aa)
	STAT3	Signal transducer and activator of transcription. (790 aa)
	PXDN	Peroxidasin homolog. (1479 aa)
	HNF4A	Hepatocyte nuclear factor 4 alpha. (474 aa)
	GATA1	GATA binding protein 1. (413 aa)
	HJV	HFE2 isoform 1. (426 aa)
	FTH1	Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. (183 aa)
	IL6-2	Interleukin 6. (234 aa)
	HFE	Hereditary hemochromatosis protein homolog; Binds to transferrin receptor (TFR) and reduces its affinity for iron-loaded transferrin. (348 aa)
	APOC3-2	Apolipoprotein C3. (99 aa)
	IL6	Interleukin 6 (Interferon, beta 2). (234 aa)
	HEPH	HEPH isoform 1; Belongs to the multicopper oxidase family. (1212 aa)
	FTL	Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. (182 aa)
	GPX1	Glutathione peroxidase 1; Protects the hemoglobin in erythrocytes from oxidative breakdown. (200 aa)
	APOC3	APOC3 isoform 2. (99 aa)
	TFRC	Transferrin receptor (P90, CD71). (760 aa)
	GPT	Glutamic--pyruvic transaminase. (496 aa)
	FTHL17	Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. (183 aa)
	PXDNL	PXDNL isoform 2. (1463 aa)
	TFR2	Transferrin receptor 2. (801 aa)
	PPARA	Peroxisome proliferator-activated receptor alpha. (467 aa)
	SLC27A5	SLC27A5 isoform 3. (690 aa)
	HAMP	Hepcidin antimicrobial peptide. (84 aa)

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APOC3	APOC3-2	ENSPTRP00000047629	ENSPTRP00000077121	APOC3 isoform 2.	Apolipoprotein C3.	0.544
APOC3	HMGCS2	ENSPTRP00000047629	ENSPTRP00000002014	APOC3 isoform 2.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.501
APOC3	HNF4A	ENSPTRP00000047629	ENSPTRP00000087554	APOC3 isoform 2.	Hepatocyte nuclear factor 4 alpha.	0.453
APOC3	PPARA	ENSPTRP00000047629	ENSPTRP00000025003	APOC3 isoform 2.	Peroxisome proliferator-activated receptor alpha.	0.503
APOC3	SLC27A5	ENSPTRP00000047629	ENSPTRP00000019940	APOC3 isoform 2.	SLC27A5 isoform 3.	0.591
APOC3-2	APOC3	ENSPTRP00000077121	ENSPTRP00000047629	Apolipoprotein C3.	APOC3 isoform 2.	0.544
APOC3-2	HMGCS2	ENSPTRP00000077121	ENSPTRP00000002014	Apolipoprotein C3.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.501
APOC3-2	HNF4A	ENSPTRP00000077121	ENSPTRP00000087554	Apolipoprotein C3.	Hepatocyte nuclear factor 4 alpha.	0.454
APOC3-2	PPARA	ENSPTRP00000077121	ENSPTRP00000025003	Apolipoprotein C3.	Peroxisome proliferator-activated receptor alpha.	0.504
APOC3-2	SLC27A5	ENSPTRP00000077121	ENSPTRP00000019940	Apolipoprotein C3.	SLC27A5 isoform 3.	0.592
FTH1	FTHL17	ENSPTRP00000083820	ENSPTRP00000037331	Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.	Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.	0.901
FTH1	FTL	ENSPTRP00000083820	ENSPTRP00000060398	Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.	Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.	0.982
FTH1	HAMP	ENSPTRP00000083820	ENSPTRP00000018553	Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.	Hepcidin antimicrobial peptide.	0.441
FTH1	TFR2	ENSPTRP00000083820	ENSPTRP00000033379	Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.	Transferrin receptor 2.	0.509
FTH1	TFRC	ENSPTRP00000083820	ENSPTRP00000046807	Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.	Transferrin receptor (P90, CD71).	0.844
FTHL17	FTH1	ENSPTRP00000037331	ENSPTRP00000083820	Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.	Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.	0.901
FTHL17	FTL	ENSPTRP00000037331	ENSPTRP00000060398	Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.	Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.	0.950
FTHL17	TFR2	ENSPTRP00000037331	ENSPTRP00000033379	Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.	Transferrin receptor 2.	0.539
FTHL17	TFRC	ENSPTRP00000037331	ENSPTRP00000046807	Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.	Transferrin receptor (P90, CD71).	0.640
FTL	FTH1	ENSPTRP00000060398	ENSPTRP00000083820	Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.	Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.	0.982