STRINGSTRING
PAX6 PAX6 HIST1H3A HIST1H3A H3-4 H3-4 FGF2 FGF2 NDC1 NDC1 KCNIP2 KCNIP2 LOC107966300 LOC107966300 SATB2 SATB2 ISL1 ISL1 LOC112209457 LOC112209457 DLX1 DLX1 CK820_G0018745 CK820_G0018745 TBR1 TBR1 MDGA1 MDGA1 H3C13 H3C13 FOXG1 FOXG1 RORB RORB
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PAX6PAX6 isoform 13. (436 aa)
HIST1H3AH3F3B isoform 13. (136 aa)
H3-4HIST3H3 isoform 1. (136 aa)
FGF2Fibroblast growth factor 2; Acts as a ligand for FGFR1, FGFR2, FGFR3 and FGFR4. Also acts as an integrin ligand which is required for FGF2 signaling. Binds to integrin ITGAV:ITGB3. Plays an important role in the regulation of cell survival, cell division, cell differentiation and cell migration. Functions as a potent mitogen in vitro. Can induce angiogenesis. (288 aa)
NDC1Transmembrane protein 48. (776 aa)
KCNIP2Potassium voltage-gated channel interacting protein 2. (285 aa)
LOC107966300Histone H3. (136 aa)
SATB2DNA-binding protein SATB. (733 aa)
ISL1ISL LIM homeobox 1. (349 aa)
LOC112209457HIST1H3A isoform 1. (136 aa)
DLX1Distal-less homeobox 1. (255 aa)
CK820_G0018745FZD8 isoform 1; Belongs to the G-protein coupled receptor Fz/Smo family. (628 aa)
TBR1T-box brain transcription factor 1. (682 aa)
MDGA1MAM domain containing glycosylphosphatidylinositol anchor 1. (955 aa)
H3C13HIST2H3A isoform 1. (136 aa)
FOXG1FOXG1 isoform 8. (489 aa)
RORBRAR related orphan receptor B. (482 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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