node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACTB | ALB | ENSPTRP00000058292 | ENSPTRP00000056218 | Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. | ALB isoform 2. | 0.755 |
ACTB | KRAS | ENSPTRP00000058292 | ENSPTRP00000084588 | Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. | V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog. | 0.509 |
ACTB | MAPK1 | ENSPTRP00000058292 | ENSPTRP00000024313 | Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. | 0.516 |
ACTB | PXDN | ENSPTRP00000058292 | ENSPTRP00000090912 | Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. | Peroxidasin homolog. | 0.855 |
ACTB | PXDNL | ENSPTRP00000058292 | ENSPTRP00000034664 | Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. | PXDNL isoform 2. | 0.855 |
ACTB | SRC | ENSPTRP00000058292 | ENSPTRP00000076797 | Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. | Tyrosine-protein kinase. | 0.541 |
ACTB | TP53 | ENSPTRP00000058292 | ENSPTRP00000014836 | Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | 0.651 |
ALB | ACTB | ENSPTRP00000056218 | ENSPTRP00000058292 | ALB isoform 2. | Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. | 0.755 |
ALB | MAPK1 | ENSPTRP00000056218 | ENSPTRP00000024313 | ALB isoform 2. | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. | 0.423 |
ALB | PXDN | ENSPTRP00000056218 | ENSPTRP00000090912 | ALB isoform 2. | Peroxidasin homolog. | 0.854 |
ALB | PXDNL | ENSPTRP00000056218 | ENSPTRP00000034664 | ALB isoform 2. | PXDNL isoform 2. | 0.854 |
ALB | SRC | ENSPTRP00000056218 | ENSPTRP00000076797 | ALB isoform 2. | Tyrosine-protein kinase. | 0.527 |
ALB | TP53 | ENSPTRP00000056218 | ENSPTRP00000014836 | ALB isoform 2. | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | 0.558 |
KRAS | ACTB | ENSPTRP00000084588 | ENSPTRP00000058292 | V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog. | Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. | 0.509 |
KRAS | MAPK1 | ENSPTRP00000084588 | ENSPTRP00000024313 | V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog. | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. | 0.973 |
KRAS | PIK3CA | ENSPTRP00000084588 | ENSPTRP00000084763 | V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog. | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. | 0.923 |
KRAS | PXDN | ENSPTRP00000084588 | ENSPTRP00000090912 | V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog. | Peroxidasin homolog. | 0.405 |
KRAS | PXDNL | ENSPTRP00000084588 | ENSPTRP00000034664 | V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog. | PXDNL isoform 2. | 0.405 |
KRAS | SRC | ENSPTRP00000084588 | ENSPTRP00000076797 | V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog. | Tyrosine-protein kinase. | 0.977 |
KRAS | TP53 | ENSPTRP00000084588 | ENSPTRP00000014836 | V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog. | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | 0.837 |