STRINGSTRING
IRX2 IRX2 EGR2 EGR2 HHEX HHEX MEIS2 MEIS2 IRX3 IRX3 SHH SHH IRX4 IRX4 MEIS1 MEIS1 PAX6 PAX6 POMC POMC SOX4 SOX4 PITX1 PITX1 IHH IHH
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
IRX2Iroquois homeobox 2. (471 aa)
EGR2Early growth response 2. (476 aa)
HHEXHematopoietically expressed homeobox. (270 aa)
MEIS2MEIS2 isoform 1. (477 aa)
IRX3Iroquois homeobox 3. (500 aa)
SHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (465 aa)
IRX4IRX4 isoform 3. (543 aa)
MEIS1MEIS1 isoform 7. (465 aa)
PAX6PAX6 isoform 13. (436 aa)
POMCProopiomelanocortin. (268 aa)
SOX4Transcription factor SOX. (474 aa)
PITX1Homeobox protein. (314 aa)
IHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (411 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.