33 items (Pan troglodytes) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:
	VIM	Vimentin; Vimentins are class-III intermediate filaments found in various non-epithelial cells, especially mesenchymal cells. Vimentin is attached to the nucleus, endoplasmic reticulum, and mitochondria, either laterally or terminally. (466 aa)
	NBPF7	NBPF9 isoform 4. (242 aa)
	ADGRG1	Adhesion G-protein coupled receptor G1; Receptor involved in cell adhesion and probably in cell-cell interactions. Mediates cell matrix adhesion in developing neurons and hematopoietic stem cells. Receptor for collagen III/COL3A1 in the developing brain and involved in regulation of cortical development, specifically in maintenance of the pial basement membrane integrity and in cortical lamination. Binding to the COL3A1 ligand inhibits neuronal migration and activates the RhoA pathway by coupling to GNA13 and possibly GNA12. Plays a role in the maintenance of hematopoietic stem cells a [...] (693 aa)
	ADAM30	ADAM30 isoform 1. (794 aa)
	MICB	MHC class I polypeptide-related sequence B. (383 aa)
	ITGAV	Integrin, alpha V (Vitronectin receptor, alpha polypeptide, antigen CD51); Belongs to the integrin alpha chain family. (1048 aa)
	SOX2	SRY-box transcription factor 2. (319 aa)
	DHRS4L1	DHRS4 isoform 8. (262 aa)
	FAM72A	Uncharacterized protein. (149 aa)
	CK820_G0018745	FZD8 isoform 1; Belongs to the G-protein coupled receptor Fz/Smo family. (628 aa)
	NOTCH1	NOTCH1 isoform 1. (2555 aa)
	DLL1	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (723 aa)
	NEUROG1	NEUROG1 isoform 1. (237 aa)
	GTF2H2C	General transcription factor IIH subunit. (395 aa)
	EGF	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1207 aa)
	TBC1D1	TBC1 (Tre-2/USP6, BUB2, cdc16) domain family, member 1. (1168 aa)
	EOMES	EOMES isoform 2. (704 aa)
	PCNA	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa)
	TGFB1	Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
	ZNF98	Zinc finger protein 98. (559 aa)
	NOTCH3	NOTCH3 isoform 1. (2321 aa)
	GAPDH	Glyceraldehyde-3-phosphate dehydrogenase. (335 aa)
	FGFR2	Fibroblast growth factor receptor. (841 aa)
	STX12	STX12 isoform 1; Belongs to the syntaxin family. (276 aa)
	FABP7	Fatty acid binding protein 7; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (166 aa)
	PTTG2	PTTG2 isoform 1. (196 aa)
	FGFR3	Fibroblast growth factor receptor. (808 aa)
	PDGFD	Platelet derived growth factor D. (370 aa)
	DHRS4	Dehydrogenase/reductase (SDR family) member 4. (278 aa)
	FOXP2	Forkhead box protein P2; Transcriptional repressor that may play a role in the specification and differentiation of lung epithelium. May also play a role in developing neural, gastrointestinal and cardiovascular tissues. Can act with CTBP1 to synergistically repress transcription but CTPBP1 is not essential. Plays a role in synapse formation by regulating SRPX2 levels (By similarity). (741 aa)
	HOPX	HOPX isoform 3. (112 aa)
	PAX6	PAX6 isoform 13. (436 aa)
	GFAP	Glial fibrillary acidic protein; Belongs to the intermediate filament family. (505 aa)

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADAM30	ADGRG1	ENSPTRP00000051928	ENSPTRP00000054569	ADAM30 isoform 1.	Adhesion G-protein coupled receptor G1; Receptor involved in cell adhesion and probably in cell-cell interactions. Mediates cell matrix adhesion in developing neurons and hematopoietic stem cells. Receptor for collagen III/COL3A1 in the developing brain and involved in regulation of cortical development, specifically in maintenance of the pial basement membrane integrity and in cortical lamination. Binding to the COL3A1 ligand inhibits neuronal migration and activates the RhoA pathway by coupling to GNA13 and possibly GNA12. Plays a role in the maintenance of hematopoietic stem cells a [...]	0.403
ADAM30	FABP7	ENSPTRP00000051928	ENSPTRP00000093433	ADAM30 isoform 1.	Fatty acid binding protein 7; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.	0.424
ADAM30	FAM72A	ENSPTRP00000051928	ENSPTRP00000041038	ADAM30 isoform 1.	Uncharacterized protein.	0.540
ADAM30	ITGAV	ENSPTRP00000051928	ENSPTRP00000048970	ADAM30 isoform 1.	Integrin, alpha V (Vitronectin receptor, alpha polypeptide, antigen CD51); Belongs to the integrin alpha chain family.	0.402
ADAM30	NBPF7	ENSPTRP00000051928	ENSPTRP00000058531	ADAM30 isoform 1.	NBPF9 isoform 4.	0.668
ADAM30	PTTG2	ENSPTRP00000051928	ENSPTRP00000092610	ADAM30 isoform 1.	PTTG2 isoform 1.	0.453
ADAM30	STX12	ENSPTRP00000051928	ENSPTRP00000000729	ADAM30 isoform 1.	STX12 isoform 1; Belongs to the syntaxin family.	0.598
ADAM30	TBC1D1	ENSPTRP00000051928	ENSPTRP00000027512	ADAM30 isoform 1.	TBC1 (Tre-2/USP6, BUB2, cdc16) domain family, member 1.	0.584
ADGRG1	ADAM30	ENSPTRP00000054569	ENSPTRP00000051928	Adhesion G-protein coupled receptor G1; Receptor involved in cell adhesion and probably in cell-cell interactions. Mediates cell matrix adhesion in developing neurons and hematopoietic stem cells. Receptor for collagen III/COL3A1 in the developing brain and involved in regulation of cortical development, specifically in maintenance of the pial basement membrane integrity and in cortical lamination. Binding to the COL3A1 ligand inhibits neuronal migration and activates the RhoA pathway by coupling to GNA13 and possibly GNA12. Plays a role in the maintenance of hematopoietic stem cells a [...]	ADAM30 isoform 1.	0.403
ADGRG1	DLL1	ENSPTRP00000054569	ENSPTRP00000032142	Adhesion G-protein coupled receptor G1; Receptor involved in cell adhesion and probably in cell-cell interactions. Mediates cell matrix adhesion in developing neurons and hematopoietic stem cells. Receptor for collagen III/COL3A1 in the developing brain and involved in regulation of cortical development, specifically in maintenance of the pial basement membrane integrity and in cortical lamination. Binding to the COL3A1 ligand inhibits neuronal migration and activates the RhoA pathway by coupling to GNA13 and possibly GNA12. Plays a role in the maintenance of hematopoietic stem cells a [...]	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.606
ADGRG1	FABP7	ENSPTRP00000054569	ENSPTRP00000093433	Adhesion G-protein coupled receptor G1; Receptor involved in cell adhesion and probably in cell-cell interactions. Mediates cell matrix adhesion in developing neurons and hematopoietic stem cells. Receptor for collagen III/COL3A1 in the developing brain and involved in regulation of cortical development, specifically in maintenance of the pial basement membrane integrity and in cortical lamination. Binding to the COL3A1 ligand inhibits neuronal migration and activates the RhoA pathway by coupling to GNA13 and possibly GNA12. Plays a role in the maintenance of hematopoietic stem cells a [...]	Fatty acid binding protein 7; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.	0.641
ADGRG1	GFAP	ENSPTRP00000054569	ENSPTRP00000062393	Adhesion G-protein coupled receptor G1; Receptor involved in cell adhesion and probably in cell-cell interactions. Mediates cell matrix adhesion in developing neurons and hematopoietic stem cells. Receptor for collagen III/COL3A1 in the developing brain and involved in regulation of cortical development, specifically in maintenance of the pial basement membrane integrity and in cortical lamination. Binding to the COL3A1 ligand inhibits neuronal migration and activates the RhoA pathway by coupling to GNA13 and possibly GNA12. Plays a role in the maintenance of hematopoietic stem cells a [...]	Glial fibrillary acidic protein; Belongs to the intermediate filament family.	0.401
ADGRG1	HOPX	ENSPTRP00000054569	ENSPTRP00000065973	Adhesion G-protein coupled receptor G1; Receptor involved in cell adhesion and probably in cell-cell interactions. Mediates cell matrix adhesion in developing neurons and hematopoietic stem cells. Receptor for collagen III/COL3A1 in the developing brain and involved in regulation of cortical development, specifically in maintenance of the pial basement membrane integrity and in cortical lamination. Binding to the COL3A1 ligand inhibits neuronal migration and activates the RhoA pathway by coupling to GNA13 and possibly GNA12. Plays a role in the maintenance of hematopoietic stem cells a [...]	HOPX isoform 3.	0.505
ADGRG1	ITGAV	ENSPTRP00000054569	ENSPTRP00000048970	Adhesion G-protein coupled receptor G1; Receptor involved in cell adhesion and probably in cell-cell interactions. Mediates cell matrix adhesion in developing neurons and hematopoietic stem cells. Receptor for collagen III/COL3A1 in the developing brain and involved in regulation of cortical development, specifically in maintenance of the pial basement membrane integrity and in cortical lamination. Binding to the COL3A1 ligand inhibits neuronal migration and activates the RhoA pathway by coupling to GNA13 and possibly GNA12. Plays a role in the maintenance of hematopoietic stem cells a [...]	Integrin, alpha V (Vitronectin receptor, alpha polypeptide, antigen CD51); Belongs to the integrin alpha chain family.	0.603
ADGRG1	NEUROG1	ENSPTRP00000054569	ENSPTRP00000029519	Adhesion G-protein coupled receptor G1; Receptor involved in cell adhesion and probably in cell-cell interactions. Mediates cell matrix adhesion in developing neurons and hematopoietic stem cells. Receptor for collagen III/COL3A1 in the developing brain and involved in regulation of cortical development, specifically in maintenance of the pial basement membrane integrity and in cortical lamination. Binding to the COL3A1 ligand inhibits neuronal migration and activates the RhoA pathway by coupling to GNA13 and possibly GNA12. Plays a role in the maintenance of hematopoietic stem cells a [...]	NEUROG1 isoform 1.	0.646
ADGRG1	NOTCH1	ENSPTRP00000054569	ENSPTRP00000036924	Adhesion G-protein coupled receptor G1; Receptor involved in cell adhesion and probably in cell-cell interactions. Mediates cell matrix adhesion in developing neurons and hematopoietic stem cells. Receptor for collagen III/COL3A1 in the developing brain and involved in regulation of cortical development, specifically in maintenance of the pial basement membrane integrity and in cortical lamination. Binding to the COL3A1 ligand inhibits neuronal migration and activates the RhoA pathway by coupling to GNA13 and possibly GNA12. Plays a role in the maintenance of hematopoietic stem cells a [...]	NOTCH1 isoform 1.	0.408
ADGRG1	NOTCH3	ENSPTRP00000054569	ENSPTRP00000018116	Adhesion G-protein coupled receptor G1; Receptor involved in cell adhesion and probably in cell-cell interactions. Mediates cell matrix adhesion in developing neurons and hematopoietic stem cells. Receptor for collagen III/COL3A1 in the developing brain and involved in regulation of cortical development, specifically in maintenance of the pial basement membrane integrity and in cortical lamination. Binding to the COL3A1 ligand inhibits neuronal migration and activates the RhoA pathway by coupling to GNA13 and possibly GNA12. Plays a role in the maintenance of hematopoietic stem cells a [...]	NOTCH3 isoform 1.	0.502
ADGRG1	PDGFD	ENSPTRP00000054569	ENSPTRP00000077954	Adhesion G-protein coupled receptor G1; Receptor involved in cell adhesion and probably in cell-cell interactions. Mediates cell matrix adhesion in developing neurons and hematopoietic stem cells. Receptor for collagen III/COL3A1 in the developing brain and involved in regulation of cortical development, specifically in maintenance of the pial basement membrane integrity and in cortical lamination. Binding to the COL3A1 ligand inhibits neuronal migration and activates the RhoA pathway by coupling to GNA13 and possibly GNA12. Plays a role in the maintenance of hematopoietic stem cells a [...]	Platelet derived growth factor D.	0.750
ADGRG1	STX12	ENSPTRP00000054569	ENSPTRP00000000729	Adhesion G-protein coupled receptor G1; Receptor involved in cell adhesion and probably in cell-cell interactions. Mediates cell matrix adhesion in developing neurons and hematopoietic stem cells. Receptor for collagen III/COL3A1 in the developing brain and involved in regulation of cortical development, specifically in maintenance of the pial basement membrane integrity and in cortical lamination. Binding to the COL3A1 ligand inhibits neuronal migration and activates the RhoA pathway by coupling to GNA13 and possibly GNA12. Plays a role in the maintenance of hematopoietic stem cells a [...]	STX12 isoform 1; Belongs to the syntaxin family.	0.443
DHRS4	FAM72A	ENSPTRP00000075635	ENSPTRP00000041038	Dehydrogenase/reductase (SDR family) member 4.	Uncharacterized protein.	0.493