17 items (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	NF1	Neurofibromin 1. (2839 aa)
	NRAS	Neuroblastoma RAS viral (V-ras) oncogene homolog. (189 aa)
	RASA2	RAS p21 protein activator 2. (849 aa)
	PSPH	Phosphoserine phosphatase. (225 aa)
	PSAT1	Phosphoserine aminotransferase. (370 aa)
	TSC2	Tuberous sclerosis 2. (1689 aa)
	SOS2	SOS Ras/Rho guanine nucleotide exchange factor 2. (1332 aa)
	FAR1	Fatty acyl-CoA reductase; Catalyzes the reduction of fatty acyl-CoA to fatty alcohols. (518 aa)
	SOS1	SOS Ras/Rac guanine nucleotide exchange factor 1. (1333 aa)
	SHMT2	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (504 aa)
	PSPH-2	Phosphoserine phosphatase. (225 aa)
	RAPGEF1	RAPGEF1 isoform 5. (1065 aa)
	DISC1	Disrupted in schizophrenia 1 protein isoform X1. (977 aa)
	CRK	V-crk sarcoma virus CT10 oncogene homolog (Avian). (304 aa)
	KRAS	V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog. (189 aa)
	AKT3	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
	RASSF7	Ras association domain family member 7. (373 aa)

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AKT3	CRK	ENSPTRP00000086046	ENSPTRP00000083173	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	V-crk sarcoma virus CT10 oncogene homolog (Avian).	0.451
AKT3	KRAS	ENSPTRP00000086046	ENSPTRP00000084588	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog.	0.530
AKT3	NRAS	ENSPTRP00000086046	ENSPTRP00000001956	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Neuroblastoma RAS viral (V-ras) oncogene homolog.	0.530
AKT3	PSPH	ENSPTRP00000086046	ENSPTRP00000032820	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Phosphoserine phosphatase.	0.443
AKT3	PSPH-2	ENSPTRP00000086046	ENSPTRP00000067271	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Phosphoserine phosphatase.	0.443
AKT3	RAPGEF1	ENSPTRP00000086046	ENSPTRP00000074530	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	RAPGEF1 isoform 5.	0.610
AKT3	RASA2	ENSPTRP00000086046	ENSPTRP00000026641	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	RAS p21 protein activator 2.	0.500
AKT3	SHMT2	ENSPTRP00000086046	ENSPTRP00000063004	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.	0.413
AKT3	SOS2	ENSPTRP00000086046	ENSPTRP00000043790	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	SOS Ras/Rho guanine nucleotide exchange factor 2.	0.414
AKT3	TSC2	ENSPTRP00000086046	ENSPTRP00000042921	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Tuberous sclerosis 2.	0.776
CRK	AKT3	ENSPTRP00000083173	ENSPTRP00000086046	V-crk sarcoma virus CT10 oncogene homolog (Avian).	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.451
CRK	KRAS	ENSPTRP00000083173	ENSPTRP00000084588	V-crk sarcoma virus CT10 oncogene homolog (Avian).	V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog.	0.416
CRK	PSPH	ENSPTRP00000083173	ENSPTRP00000032820	V-crk sarcoma virus CT10 oncogene homolog (Avian).	Phosphoserine phosphatase.	0.494
CRK	PSPH-2	ENSPTRP00000083173	ENSPTRP00000067271	V-crk sarcoma virus CT10 oncogene homolog (Avian).	Phosphoserine phosphatase.	0.494
CRK	RAPGEF1	ENSPTRP00000083173	ENSPTRP00000074530	V-crk sarcoma virus CT10 oncogene homolog (Avian).	RAPGEF1 isoform 5.	0.995
CRK	RASA2	ENSPTRP00000083173	ENSPTRP00000026641	V-crk sarcoma virus CT10 oncogene homolog (Avian).	RAS p21 protein activator 2.	0.561
CRK	SHMT2	ENSPTRP00000083173	ENSPTRP00000063004	V-crk sarcoma virus CT10 oncogene homolog (Avian).	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.	0.450
CRK	SOS1	ENSPTRP00000083173	ENSPTRP00000052023	V-crk sarcoma virus CT10 oncogene homolog (Avian).	SOS Ras/Rac guanine nucleotide exchange factor 1.	0.935
CRK	SOS2	ENSPTRP00000083173	ENSPTRP00000043790	V-crk sarcoma virus CT10 oncogene homolog (Avian).	SOS Ras/Rho guanine nucleotide exchange factor 2.	0.704
DISC1	RASA2	ENSPTRP00000078918	ENSPTRP00000026641	Disrupted in schizophrenia 1 protein isoform X1.	RAS p21 protein activator 2.	0.480