13 items (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	IL2	Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family. (153 aa)
	SRSF5	Serine and arginine rich splicing factor 5. (272 aa)
	APOBEC1	APOBEC1 isoform 2. (236 aa)
	TUB	Tubby-like protein; Belongs to the TUB family. (561 aa)
	CBX6	Chromobox homolog 6. (412 aa)
	AICDA	Activation induced cytidine deaminase. (199 aa)
	U2AF2	U2 snRNP auxiliary factor large subunit; Necessary for the splicing of pre-mRNA. Belongs to the splicing factor SR family. (475 aa)
	PTBP1	PTBP1 isoform 2. (680 aa)
	CBX7	Chromobox homolog 7. (272 aa)
	HNRNPC	HNRNPC isoform 14. (321 aa)
	SPX	Chromosome 12 open reading frame 39. (116 aa)
	CD4	T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...] (458 aa)
	CCR7	C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family. (378 aa)

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AICDA	CBX6	ENSPTRP00000091417	ENSPTRP00000092047	Activation induced cytidine deaminase.	Chromobox homolog 6.	0.801
AICDA	CBX7	ENSPTRP00000091417	ENSPTRP00000076004	Activation induced cytidine deaminase.	Chromobox homolog 7.	0.701
AICDA	CD4	ENSPTRP00000091417	ENSPTRP00000054833	Activation induced cytidine deaminase.	T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...]	0.570
APOBEC1	CBX6	ENSPTRP00000007882	ENSPTRP00000092047	APOBEC1 isoform 2.	Chromobox homolog 6.	0.549
APOBEC1	CBX7	ENSPTRP00000007882	ENSPTRP00000076004	APOBEC1 isoform 2.	Chromobox homolog 7.	0.438
CBX6	AICDA	ENSPTRP00000092047	ENSPTRP00000091417	Chromobox homolog 6.	Activation induced cytidine deaminase.	0.801
CBX6	APOBEC1	ENSPTRP00000092047	ENSPTRP00000007882	Chromobox homolog 6.	APOBEC1 isoform 2.	0.549
CBX6	CBX7	ENSPTRP00000092047	ENSPTRP00000076004	Chromobox homolog 6.	Chromobox homolog 7.	0.674
CBX6	SPX	ENSPTRP00000092047	ENSPTRP00000058639	Chromobox homolog 6.	Chromosome 12 open reading frame 39.	0.604
CBX6	SRSF5	ENSPTRP00000092047	ENSPTRP00000010998	Chromobox homolog 6.	Serine and arginine rich splicing factor 5.	0.526
CBX6	TUB	ENSPTRP00000092047	ENSPTRP00000005811	Chromobox homolog 6.	Tubby-like protein; Belongs to the TUB family.	0.413
CBX6	U2AF2	ENSPTRP00000092047	ENSPTRP00000091126	Chromobox homolog 6.	U2 snRNP auxiliary factor large subunit; Necessary for the splicing of pre-mRNA. Belongs to the splicing factor SR family.	0.514
CBX7	AICDA	ENSPTRP00000076004	ENSPTRP00000091417	Chromobox homolog 7.	Activation induced cytidine deaminase.	0.701
CBX7	APOBEC1	ENSPTRP00000076004	ENSPTRP00000007882	Chromobox homolog 7.	APOBEC1 isoform 2.	0.438
CBX7	CBX6	ENSPTRP00000076004	ENSPTRP00000092047	Chromobox homolog 7.	Chromobox homolog 6.	0.674
CBX7	SPX	ENSPTRP00000076004	ENSPTRP00000058639	Chromobox homolog 7.	Chromosome 12 open reading frame 39.	0.507
CCR7	CD4	ENSPTRP00000053043	ENSPTRP00000054833	C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family.	T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...]	0.872
CCR7	IL2	ENSPTRP00000053043	ENSPTRP00000028193	C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family.	Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family.	0.716
CD4	AICDA	ENSPTRP00000054833	ENSPTRP00000091417	T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...]	Activation induced cytidine deaminase.	0.570
CD4	CCR7	ENSPTRP00000054833	ENSPTRP00000053043	T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...]	C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family.	0.872