STRINGSTRING
FGF19 FGF19 FGF4 FGF4 FGF3 FGF3 CCND2 CCND2 GAPDH GAPDH FGF9 FGF9 FGF14 FGF14 FGF7 FGF7 FGF21 FGF21 HIST1H3A HIST1H3A E2F1 E2F1 FGF5 FGF5 CCNA2 CCNA2 FGF1 FGF1 LOC112209457 LOC112209457 PCM1 PCM1 FGF17 FGF17 FGF16 FGF16 H3C13 H3C13 FGF22 FGF22 CDK2 CDK2 FGF13 FGF13 HGF HGF FGF8 FGF8 INS INS LOC107966300 LOC107966300 FGF10 FGF10 FGF6 FGF6 FGF20 FGF20 CCND1 CCND1 CCNE1 CCNE1 FGF11 FGF11 FGF12 FGF12 E2F1-2 E2F1-2 FGF18 FGF18 H3-4 H3-4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
FGF19Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (216 aa)
FGF4Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (206 aa)
FGF3Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (239 aa)
CCND2CCND2 isoform 1; Belongs to the cyclin family. (289 aa)
GAPDHGlyceraldehyde-3-phosphate dehydrogenase. (335 aa)
FGF9Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
FGF14Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (252 aa)
FGF7Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa)
FGF21Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (209 aa)
HIST1H3AH3F3B isoform 13. (136 aa)
E2F1E2F transcription factor 1. (437 aa)
FGF5Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (268 aa)
CCNA2CCNA2 isoform 1; Belongs to the cyclin family. (432 aa)
FGF1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa)
LOC112209457HIST1H3A isoform 1. (136 aa)
PCM1Pericentriolar material 1. (2024 aa)
FGF17Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (216 aa)
FGF16Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
H3C13HIST2H3A isoform 1. (136 aa)
FGF22Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (170 aa)
CDK2CDK2 isoform 4; Belongs to the protein kinase superfamily. (346 aa)
FGF13Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (255 aa)
HGFHepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. (812 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (244 aa)
INSInsulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (200 aa)
LOC107966300Histone H3. (136 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
FGF6Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
FGF20Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (211 aa)
CCND1CCND1 isoform 1; Belongs to the cyclin family. (295 aa)
CCNE1CCNE1 isoform 1; Belongs to the cyclin family. (411 aa)
FGF11Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (197 aa)
FGF12Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (243 aa)
E2F1-2E2F transcription factor 1. (437 aa)
FGF18Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
H3-4HIST3H3 isoform 1. (136 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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