STRINGSTRING
LPCAT3 LPCAT3 HPX HPX FLVCR1 FLVCR1 CD163 CD163 FXN FXN FTH1 FTH1 FLVCR2 FLVCR2 SAT1 SAT1 PCBP2 PCBP2 FECH FECH FTL FTL ABCB10 ABCB10 SAT1-2 SAT1-2 AMBP AMBP NCOA4 NCOA4 FTMT FTMT FBXL5 FBXL5 ALAS1 ALAS1 HMOX1 HMOX1 SLC40A1 SLC40A1 STEAP3 STEAP3 PCBP1 PCBP1 HAMP HAMP JMJD6 JMJD6
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LPCAT3Lysophosphatidylcholine acyltransferase 3; Belongs to the membrane-bound acyltransferase family. (487 aa)
HPXHemopexin; Binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation. (462 aa)
FLVCR1Feline leukemia virus subgroup C cellular receptor 1. (569 aa)
CD163CD163 isoform 1. (1156 aa)
FXNFXN isoform 1. (210 aa)
FTH1Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. (183 aa)
FLVCR2FLVCR2 isoform 1. (525 aa)
SAT1Spermidine/spermine N1-acetyltransferase 1. (171 aa)
PCBP2Poly(rC) binding protein 2. (366 aa)
FECHFerrochelatase, mitochondrial; Catalyzes the ferrous insertion into protoporphyrin IX. (429 aa)
FTLFerritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. (182 aa)
ABCB10ATP binding cassette subfamily B member 10. (738 aa)
SAT1-2Spermidine/spermine N1-acetyltransferase 1. (171 aa)
AMBPAlpha-1-microglobulin/bikunin precursor. (364 aa)
NCOA4Nuclear receptor coactivator 4. (650 aa)
FTMTFerritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. (242 aa)
FBXL5F-box and leucine-rich repeat protein 5. (691 aa)
ALAS15-aminolevulinate synthase. (640 aa)
HMOX1Heme oxygenase; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. (311 aa)
SLC40A1Solute carrier family 40 protein; May be involved in iron transport and iron homeostasis. Belongs to the ferroportin (FP) (TC 2.A.100) family. SLC40A subfamily. (571 aa)
STEAP3STEAP3 metalloreductase. (498 aa)
PCBP1Poly(rC) binding protein 1. (356 aa)
HAMPHepcidin antimicrobial peptide. (84 aa)
JMJD6Jumonji domain containing 6, arginine demethylase and lysine hydroxylase. (420 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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