STRINGSTRING
SATB2 SATB2 APOD APOD NPC1 NPC1 NEUROG2 NEUROG2 CCND1 CCND1 UNC13A UNC13A NR2F1 NR2F1 NEUROD2 NEUROD2 CUX2 CUX2 MEF2C MEF2C FABP7 FABP7 VIM VIM EMX2 EMX2 NPC2 NPC2 AQP4 AQP4 GAD1 GAD1 NEU2 NEU2 ITPR2 ITPR2 EOMES EOMES PDGFRA PDGFRA ADAMTS3 ADAMTS3 NEUROD6 NEUROD6 PPP1R17 PPP1R17 LHX2 LHX2 CK820_G0018745 CK820_G0018745 APOLD1 APOLD1 TBR1 TBR1 CCIN CCIN HMGA2 HMGA2 BCL11B BCL11B FOXG1 FOXG1 LHX1 LHX1 CX3CR1 CX3CR1 PLXNA4 PLXNA4 STMN2 STMN2 OLIG1 OLIG1 ENSPTRP00000065099 ENSPTRP00000065099 PAX6 PAX6 HOPX HOPX DCX DCX CAMK2B CAMK2B DOCK9 DOCK9 NRXN2 NRXN2 NR2F2 NR2F2 FEZF2 FEZF2 OLIG1-2 OLIG1-2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SATB2DNA-binding protein SATB. (733 aa)
APODApolipoprotein D. (215 aa)
NPC1Niemann-Pick disease, type C1. (1280 aa)
NEUROG2NEUROG2 isoform 1. (272 aa)
CCND1CCND1 isoform 1; Belongs to the cyclin family. (295 aa)
UNC13AUNC13A isoform 2. (1693 aa)
NR2F1Nuclear receptor subfamily 2 group F member 1. (423 aa)
NEUROD2Neurogenic differentiation factor. (382 aa)
CUX2Homeobox protein cut-like. (1489 aa)
MEF2CMyocyte enhancer factor 2C. (483 aa)
FABP7Fatty acid binding protein 7; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (166 aa)
VIMVimentin; Vimentins are class-III intermediate filaments found in various non-epithelial cells, especially mesenchymal cells. Vimentin is attached to the nucleus, endoplasmic reticulum, and mitochondria, either laterally or terminally. (466 aa)
EMX2Empty spiracles homeobox 2. (252 aa)
NPC2NPC intracellular cholesterol transporter 2; Intracellular cholesterol transporter which acts in concert with NPC1 and plays an important role in the egress of cholesterol from the lysosomal compartment. Unesterified cholesterol that has been released from LDLs in the lumen of the late endosomes/lysosomes is transferred by NPC2 to the cholesterol-binding pocket in the N-terminal domain of NPC1. May bind and mobilize cholesterol that is associated with membranes. NPC2 binds cholesterol with a 1:1 stoichiometry. Can bind a variety of sterols, including lathosterol, desmosterol and the pl [...] (221 aa)
AQP4AQP4 isoform 1; Belongs to the MIP/aquaporin (TC 1.A.8) family. (323 aa)
GAD1Glutamate decarboxylase 1; Catalyzes the production of GABA; Belongs to the group II decarboxylase family. (594 aa)
NEU2Neuraminidase 2. (380 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor, type 2. (2727 aa)
EOMESEOMES isoform 2. (704 aa)
PDGFRAT0011027 isoform 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1102 aa)
ADAMTS3ADAM metallopeptidase with thrombospondin type 1 motif 3. (1205 aa)
NEUROD6Neurogenic differentiation factor. (337 aa)
PPP1R17Protein phosphatase 1 regulatory subunit 17. (155 aa)
LHX2LHX2 isoform 1. (406 aa)
CK820_G0018745FZD8 isoform 1; Belongs to the G-protein coupled receptor Fz/Smo family. (628 aa)
APOLD1Apolipoprotein L domain containing 1. (279 aa)
TBR1T-box brain transcription factor 1. (682 aa)
CCINCCIN isoform 1. (588 aa)
HMGA2High mobility group AT-hook 2. (147 aa)
BCL11BBAF chromatin remodeling complex subunit BCL11B. (894 aa)
FOXG1FOXG1 isoform 8. (489 aa)
LHX1LIM/homeobox protein Lhx1; Potential transcription factor. May play a role in early mesoderm formation and later in lateral mesoderm differentiation and neurogenesis (By similarity). (406 aa)
CX3CR1C-X3-C motif chemokine receptor 1; Belongs to the G-protein coupled receptor 1 family. (387 aa)
PLXNA4PLXNA4 isoform 1. (1894 aa)
STMN2Stathmin; Belongs to the stathmin family. (221 aa)
OLIG1OLIG1 isoform 2. (272 aa)
ENSPTRP00000065099annotation not available (337 aa)
PAX6PAX6 isoform 13. (436 aa)
HOPXHOPX isoform 3. (112 aa)
DCXDCX isoform 5. (420 aa)
CAMK2BCalcium/calmodulin dependent protein kinase II beta. (666 aa)
DOCK9Dedicator of cytokinesis 9; Belongs to the DOCK family. (2081 aa)
NRXN2NRXN2 isoform 2. (1712 aa)
NR2F2Nuclear receptor subfamily 2, group F, member 2. (414 aa)
FEZF2FEZ family zinc finger 2. (463 aa)
OLIG1-2OLIG1 isoform 1. (272 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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