STRINGSTRING
DLL1 DLL1 DTX1 DTX1 RAG2 RAG2 CD34 CD34 CD38 CD38 VPREB3 VPREB3 JAG1 JAG1 CD19 CD19 CHD4 CHD4 GATA3 GATA3 TBX21 TBX21 DLL4 DLL4 NOTCH2 NOTCH2 IL7R IL7R PHF6 PHF6 IL7 IL7 RAG1 RAG1 CD200 CD200 ENSPTRP00000060300 ENSPTRP00000060300 BCL11B BCL11B RBBP7 RBBP7 HES4 HES4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (723 aa)
DTX1Deltex E3 ubiquitin ligase 1. (620 aa)
RAG2Recombination activating 2. (527 aa)
CD34CD34 isoform 1. (328 aa)
CD38CD38 isoform 1. (300 aa)
VPREB3V-set pre-B cell surrogate light chain 3. (123 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1218 aa)
CD19CD19 isoform 1. (557 aa)
CHD4Chromodomain helicase DNA binding protein 4. (1912 aa)
GATA3GATA binding protein 3. (444 aa)
TBX21T-box transcription factor 21. (535 aa)
DLL4Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (696 aa)
NOTCH2NOTCH2 isoform 1. (2612 aa)
IL7RInterleukin 7 receptor. (459 aa)
PHF6PHD finger protein 6. (366 aa)
IL7Interleukin-7; Hematopoietic growth factor capable of stimulating the proliferation of lymphoid progenitors. It is important for proliferation during certain stages of B-cell maturation. Belongs to the IL-7/IL-9 family. (179 aa)
RAG1V(D)J recombination-activating protein 1; Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T- lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break [...] (955 aa)
CD200CD200 isoform 4. (294 aa)
ENSPTRP00000060300annotation not available (221 aa)
BCL11BBAF chromatin remodeling complex subunit BCL11B. (894 aa)
RBBP7RBBP7 isoform 5. (469 aa)
HES4Hes family bHLH transcription factor 4. (221 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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