STRINGSTRING
LHX5 LHX5 MTOR MTOR PAX7 PAX7 VIM VIM ALX1 ALX1 LUM LUM TOP2A TOP2A GBX2 GBX2 AIF1 AIF1 NEUROD6 NEUROD6 PPP1R17 PPP1R17 NOTCH1 NOTCH1 HES5 HES5 SOX2 SOX2 BCL11B BCL11B FOXG1 FOXG1 RELN RELN ENSPTRP00000065099 ENSPTRP00000065099 PAX6 PAX6 HOPX HOPX DCX DCX ID4 ID4 TLE4 TLE4 CALB2 CALB2 NKX2-1 NKX2-1 CDC42 CDC42 FOS FOS SATB2 SATB2 DLK1 DLK1 HES5-2 HES5-2 NHLH1 NHLH1 FGF10 FGF10 NEUROG2 NEUROG2 NTRK3 NTRK3 NR4A2 NR4A2 MEF2C MEF2C
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LHX5LHX5 isoform 2. (402 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2549 aa)
PAX7PAX7 isoform 2. (505 aa)
VIMVimentin; Vimentins are class-III intermediate filaments found in various non-epithelial cells, especially mesenchymal cells. Vimentin is attached to the nucleus, endoplasmic reticulum, and mitochondria, either laterally or terminally. (466 aa)
ALX1ALX homeobox 1. (326 aa)
LUMLUM isoform 1. (338 aa)
TOP2ADNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1531 aa)
GBX2Gastrulation brain homeobox 2. (348 aa)
AIF1Allograft inflammatory factor 1. (147 aa)
NEUROD6Neurogenic differentiation factor. (337 aa)
PPP1R17Protein phosphatase 1 regulatory subunit 17. (155 aa)
NOTCH1NOTCH1 isoform 1. (2555 aa)
HES5Hes family bHLH transcription factor 5. (165 aa)
SOX2SRY-box transcription factor 2. (319 aa)
BCL11BBAF chromatin remodeling complex subunit BCL11B. (894 aa)
FOXG1FOXG1 isoform 8. (489 aa)
RELNRELN isoform 3. (3460 aa)
ENSPTRP00000065099annotation not available (337 aa)
PAX6PAX6 isoform 13. (436 aa)
HOPXHOPX isoform 3. (112 aa)
DCXDCX isoform 5. (420 aa)
ID4Inhibitor of DNA binding 4, dominant negative helix-loop-helix protein. (161 aa)
TLE4TLE family member 4, transcriptional corepressor. (805 aa)
CALB2CALB2 isoform 1. (271 aa)
NKX2-1NKX2-1 isoform 1. (401 aa)
CDC42Cell division cycle 42 (GTP binding protein, 25kDa). (191 aa)
FOSFos proto-oncogene, AP-1 transcription factor subunit. (380 aa)
SATB2DNA-binding protein SATB. (733 aa)
DLK1Delta like non-canonical Notch ligand 1. (383 aa)
HES5-2Hes family bHLH transcription factor 5. (165 aa)
NHLH1Nescient helix-loop-helix 1. (133 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
NEUROG2NEUROG2 isoform 1. (272 aa)
NTRK3NT-3 growth factor receptor; Receptor tyrosine kinase involved in nervous system and probably heart development. Upon binding of its ligand NTF3/neurotrophin-3, NTRK3 autophosphorylates and activates different signaling pathways, including the phosphatidylinositol 3-kinase/AKT and the MAPK pathways, that control cell survival and differentiation. (864 aa)
NR4A2Nuclear receptor subfamily 4, group A, member 2. (598 aa)
MEF2CMyocyte enhancer factor 2C. (483 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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