STRINGSTRING
MEF2D MEF2D VIM VIM HBB HBB GAPDH GAPDH BMP4 BMP4 SNAP25 SNAP25 GRIA2 GRIA2 LOX LOX GRIK2 GRIK2 TBR1 TBR1 DPPA5 DPPA5 MAPK12 MAPK12 EMX1 EMX1 DPPA5-2 DPPA5-2 GATA3 GATA3 PAX6 PAX6 DCX DCX FGF2 FGF2 MAPK11 MAPK11 PIK3R1 PIK3R1 BMP4-2 BMP4-2 SNAP91 SNAP91 CDH2 CDH2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MEF2DMyocyte enhancer factor 2D. (521 aa)
VIMVimentin; Vimentins are class-III intermediate filaments found in various non-epithelial cells, especially mesenchymal cells. Vimentin is attached to the nucleus, endoplasmic reticulum, and mitochondria, either laterally or terminally. (466 aa)
HBBHemoglobin subunit beta; Involved in oxygen transport from the lung to the various peripheral tissues. (147 aa)
GAPDHGlyceraldehyde-3-phosphate dehydrogenase. (335 aa)
BMP4Bone morphogenetic protein 4. (408 aa)
SNAP25Synaptosomal-associated protein 25; t-SNARE involved in the molecular regulation of neurotransmitter release. May play an important role in the synaptic function of specific neuronal systems. Associates with proteins involved in vesicle docking and membrane fusion. Regulates plasma membrane recycling through its interaction with CENPF. Modulates the gating characteristics of the delayed rectifier voltage-dependent potassium channel KCNB1 in pancreatic beta cells; Belongs to the SNAP-25 family. (206 aa)
GRIA2Glutamate ionotropic receptor AMPA type subunit 2. (883 aa)
LOXLOX isoform 1. (417 aa)
GRIK2Glutamate ionotropic receptor kainate type subunit 2. (908 aa)
TBR1T-box brain transcription factor 1. (682 aa)
DPPA5Developmental pluripotency associated 5. (116 aa)
MAPK12Mitogen-activated protein kinase. (370 aa)
EMX1Empty spiracles homeobox 1. (290 aa)
DPPA5-2Developmental pluripotency associated 5. (116 aa)
GATA3GATA binding protein 3. (444 aa)
PAX6PAX6 isoform 13. (436 aa)
DCXDCX isoform 5. (420 aa)
FGF2Fibroblast growth factor 2; Acts as a ligand for FGFR1, FGFR2, FGFR3 and FGFR4. Also acts as an integrin ligand which is required for FGF2 signaling. Binds to integrin ITGAV:ITGB3. Plays an important role in the regulation of cell survival, cell division, cell differentiation and cell migration. Functions as a potent mitogen in vitro. Can induce angiogenesis. (288 aa)
MAPK11Mitogen-activated protein kinase. (364 aa)
PIK3R1Phosphoinositide-3-kinase, regulatory subunit 1 (Alpha). (724 aa)
BMP4-2Bone morphogenetic protein 4. (408 aa)
SNAP91SNAP91 isoform 2. (907 aa)
CDH2Cadherin 2, type 1, N-cadherin (Neuronal); Cadherins are calcium-dependent cell adhesion proteins. (914 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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