20 items (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PAX6	PAX6 isoform 13. (436 aa)
	WDR26	WD repeat domain 26. (661 aa)
	OTUD7A	OTU deubiquitinase 7A. (924 aa)
	ARHGAP11A	ARHGAP11B isoform 3. (1023 aa)
	IER3IP1	Immediate early response 3 interacting protein 1. (82 aa)
	NOTCH3	NOTCH3 isoform 1. (2321 aa)
	EGF	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1207 aa)
	DLL1	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (723 aa)
	GTF2I	General transcription factor IIi. (998 aa)
	CASTOR2	GATS protein-like 2. (329 aa)
	NOTCH1	NOTCH1 isoform 1. (2555 aa)
	FAM72A	Uncharacterized protein. (149 aa)
	SOX2	SRY-box transcription factor 2. (319 aa)
	ASPM	Abnormal spindle-like microcephaly-associated protein homolog; Probable role in mitotic spindle regulation and coordination of mitotic processes. May have a preferential role in regulating neurogenesis (By similarity). (3477 aa)
	TRPM1	Transient receptor potential cation channel subfamily M member 1. (1642 aa)
	NOTCH2	NOTCH2 isoform 1. (2612 aa)
	KLF13	Kruppel-like factor 13. (288 aa)
	GTF2I-2	General transcription factor IIi. (998 aa)
	MTMR10	Myotubularin related protein 10. (778 aa)
	PDE4DIP	PDE4DIP isoform 9. (2319 aa)

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARHGAP11A	ASPM	ENSPTRP00000011730	ENSPTRP00000051373	ARHGAP11B isoform 3.	Abnormal spindle-like microcephaly-associated protein homolog; Probable role in mitotic spindle regulation and coordination of mitotic processes. May have a preferential role in regulating neurogenesis (By similarity).	0.857
ARHGAP11A	CASTOR2	ENSPTRP00000011730	ENSPTRP00000033012	ARHGAP11B isoform 3.	GATS protein-like 2.	0.452
ARHGAP11A	FAM72A	ENSPTRP00000011730	ENSPTRP00000041038	ARHGAP11B isoform 3.	Uncharacterized protein.	0.793
ARHGAP11A	GTF2I	ENSPTRP00000011730	ENSPTRP00000032997	ARHGAP11B isoform 3.	General transcription factor IIi.	0.512
ARHGAP11A	GTF2I-2	ENSPTRP00000011730	ENSPTRP00000085881	ARHGAP11B isoform 3.	General transcription factor IIi.	0.494
ARHGAP11A	IER3IP1	ENSPTRP00000011730	ENSPTRP00000017006	ARHGAP11B isoform 3.	Immediate early response 3 interacting protein 1.	0.599
ARHGAP11A	MTMR10	ENSPTRP00000011730	ENSPTRP00000086062	ARHGAP11B isoform 3.	Myotubularin related protein 10.	0.449
ARHGAP11A	OTUD7A	ENSPTRP00000011730	ENSPTRP00000011725	ARHGAP11B isoform 3.	OTU deubiquitinase 7A.	0.607
ARHGAP11A	TRPM1	ENSPTRP00000011730	ENSPTRP00000065010	ARHGAP11B isoform 3.	Transient receptor potential cation channel subfamily M member 1.	0.457
ARHGAP11A	WDR26	ENSPTRP00000011730	ENSPTRP00000003398	ARHGAP11B isoform 3.	WD repeat domain 26.	0.485
ASPM	ARHGAP11A	ENSPTRP00000051373	ENSPTRP00000011730	Abnormal spindle-like microcephaly-associated protein homolog; Probable role in mitotic spindle regulation and coordination of mitotic processes. May have a preferential role in regulating neurogenesis (By similarity).	ARHGAP11B isoform 3.	0.857
ASPM	IER3IP1	ENSPTRP00000051373	ENSPTRP00000017006	Abnormal spindle-like microcephaly-associated protein homolog; Probable role in mitotic spindle regulation and coordination of mitotic processes. May have a preferential role in regulating neurogenesis (By similarity).	Immediate early response 3 interacting protein 1.	0.646
ASPM	PAX6	ENSPTRP00000051373	ENSPTRP00000065705	Abnormal spindle-like microcephaly-associated protein homolog; Probable role in mitotic spindle regulation and coordination of mitotic processes. May have a preferential role in regulating neurogenesis (By similarity).	PAX6 isoform 13.	0.446
ASPM	SOX2	ENSPTRP00000051373	ENSPTRP00000046752	Abnormal spindle-like microcephaly-associated protein homolog; Probable role in mitotic spindle regulation and coordination of mitotic processes. May have a preferential role in regulating neurogenesis (By similarity).	SRY-box transcription factor 2.	0.453
ASPM	TRPM1	ENSPTRP00000051373	ENSPTRP00000065010	Abnormal spindle-like microcephaly-associated protein homolog; Probable role in mitotic spindle regulation and coordination of mitotic processes. May have a preferential role in regulating neurogenesis (By similarity).	Transient receptor potential cation channel subfamily M member 1.	0.608
ASPM	WDR26	ENSPTRP00000051373	ENSPTRP00000003398	Abnormal spindle-like microcephaly-associated protein homolog; Probable role in mitotic spindle regulation and coordination of mitotic processes. May have a preferential role in regulating neurogenesis (By similarity).	WD repeat domain 26.	0.543
CASTOR2	ARHGAP11A	ENSPTRP00000033012	ENSPTRP00000011730	GATS protein-like 2.	ARHGAP11B isoform 3.	0.452
CASTOR2	FAM72A	ENSPTRP00000033012	ENSPTRP00000041038	GATS protein-like 2.	Uncharacterized protein.	0.590
CASTOR2	GTF2I	ENSPTRP00000033012	ENSPTRP00000032997	GATS protein-like 2.	General transcription factor IIi.	0.648
CASTOR2	GTF2I-2	ENSPTRP00000033012	ENSPTRP00000085881	GATS protein-like 2.	General transcription factor IIi.	0.647