13 items (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	RBPJ	Recombination signal binding protein for immunoglobulin kappa J region. (500 aa)
	PCNA	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa)
	HARS1	HARS isoform 1. (509 aa)
	NEUROD6	Neurogenic differentiation factor. (337 aa)
	PPP1R17	Protein phosphatase 1 regulatory subunit 17. (155 aa)
	TBR1	T-box brain transcription factor 1. (682 aa)
	SOX2	SRY-box transcription factor 2. (319 aa)
	ATOH1	Protein atonal homolog 1; Transcriptional regulator. Activates E box-dependent transcription in collaboration with TCF3/E47, but the activity is completely antagonized by the negative regulator of neurogenesis HES1. Plays a role in the differentiation of subsets of neural cells by activating E box-dependent transcription (By similarity). (356 aa)
	NUBP2	Cytosolic Fe-S cluster assembly factor NUBP2; Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins; Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP2/CFD1 subfamily. (270 aa)
	ENSPTRP00000065099	annotation not available (337 aa)
	PAX6	PAX6 isoform 13. (436 aa)
	HOPX	HOPX isoform 3. (112 aa)
	SATB2	DNA-binding protein SATB. (733 aa)

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATOH1	SOX2	ENSPTRP00000053413	ENSPTRP00000046752	Protein atonal homolog 1; Transcriptional regulator. Activates E box-dependent transcription in collaboration with TCF3/E47, but the activity is completely antagonized by the negative regulator of neurogenesis HES1. Plays a role in the differentiation of subsets of neural cells by activating E box-dependent transcription (By similarity).	SRY-box transcription factor 2.	0.500
ENSPTRP00000065099	PAX6	ENSPTRP00000065099	ENSPTRP00000065705	annotation not available	PAX6 isoform 13.	0.470
ENSPTRP00000065099	PPP1R17	ENSPTRP00000065099	ENSPTRP00000032557	annotation not available	Protein phosphatase 1 regulatory subunit 17.	0.434
ENSPTRP00000065099	SATB2	ENSPTRP00000065099	ENSPTRP00000080249	annotation not available	DNA-binding protein SATB.	0.482
ENSPTRP00000065099	TBR1	ENSPTRP00000065099	ENSPTRP00000046292	annotation not available	T-box brain transcription factor 1.	0.697
HARS1	PAX6	ENSPTRP00000029618	ENSPTRP00000065705	HARS isoform 1.	PAX6 isoform 13.	0.438
HARS1	SOX2	ENSPTRP00000029618	ENSPTRP00000046752	HARS isoform 1.	SRY-box transcription factor 2.	0.478
HOPX	PAX6	ENSPTRP00000065973	ENSPTRP00000065705	HOPX isoform 3.	PAX6 isoform 13.	0.560
HOPX	PPP1R17	ENSPTRP00000065973	ENSPTRP00000032557	HOPX isoform 3.	Protein phosphatase 1 regulatory subunit 17.	0.401
HOPX	SATB2	ENSPTRP00000065973	ENSPTRP00000080249	HOPX isoform 3.	DNA-binding protein SATB.	0.420
HOPX	SOX2	ENSPTRP00000065973	ENSPTRP00000046752	HOPX isoform 3.	SRY-box transcription factor 2.	0.573
NEUROD6	PAX6	ENSPTRP00000032555	ENSPTRP00000065705	Neurogenic differentiation factor.	PAX6 isoform 13.	0.470
NEUROD6	PPP1R17	ENSPTRP00000032555	ENSPTRP00000032557	Neurogenic differentiation factor.	Protein phosphatase 1 regulatory subunit 17.	0.434
NEUROD6	SATB2	ENSPTRP00000032555	ENSPTRP00000080249	Neurogenic differentiation factor.	DNA-binding protein SATB.	0.482
NEUROD6	TBR1	ENSPTRP00000032555	ENSPTRP00000046292	Neurogenic differentiation factor.	T-box brain transcription factor 1.	0.697
PAX6	ENSPTRP00000065099	ENSPTRP00000065705	ENSPTRP00000065099	PAX6 isoform 13.	annotation not available	0.470
PAX6	HARS1	ENSPTRP00000065705	ENSPTRP00000029618	PAX6 isoform 13.	HARS isoform 1.	0.438
PAX6	HOPX	ENSPTRP00000065705	ENSPTRP00000065973	PAX6 isoform 13.	HOPX isoform 3.	0.560
PAX6	NEUROD6	ENSPTRP00000065705	ENSPTRP00000032555	PAX6 isoform 13.	Neurogenic differentiation factor.	0.470
PAX6	SATB2	ENSPTRP00000065705	ENSPTRP00000080249	PAX6 isoform 13.	DNA-binding protein SATB.	0.637