7 items (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CD4	T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...] (458 aa)
	GOT2	Aspartate aminotransferase. (430 aa)
	HAMP	Hepcidin antimicrobial peptide. (84 aa)
	CCN2	CTGF isoform 1. (349 aa)
	IL6-2	Interleukin 6. (234 aa)
	IL6	Interleukin 6 (Interferon, beta 2). (234 aa)
	TFRC	Transferrin receptor (P90, CD71). (760 aa)

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CCN2	IL6	ENSPTRP00000090133	ENSPTRP00000068252	CTGF isoform 1.	Interleukin 6 (Interferon, beta 2).	0.481
CCN2	IL6-2	ENSPTRP00000090133	ENSPTRP00000080270	CTGF isoform 1.	Interleukin 6.	0.481
CD4	GOT2	ENSPTRP00000054833	ENSPTRP00000013976	T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...]	Aspartate aminotransferase.	0.618
CD4	IL6	ENSPTRP00000054833	ENSPTRP00000068252	T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...]	Interleukin 6 (Interferon, beta 2).	0.897
CD4	IL6-2	ENSPTRP00000054833	ENSPTRP00000080270	T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...]	Interleukin 6.	0.897
CD4	TFRC	ENSPTRP00000054833	ENSPTRP00000046807	T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...]	Transferrin receptor (P90, CD71).	0.628
GOT2	CD4	ENSPTRP00000013976	ENSPTRP00000054833	Aspartate aminotransferase.	T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...]	0.618
GOT2	IL6	ENSPTRP00000013976	ENSPTRP00000068252	Aspartate aminotransferase.	Interleukin 6 (Interferon, beta 2).	0.443
GOT2	IL6-2	ENSPTRP00000013976	ENSPTRP00000080270	Aspartate aminotransferase.	Interleukin 6.	0.443
HAMP	IL6	ENSPTRP00000018553	ENSPTRP00000068252	Hepcidin antimicrobial peptide.	Interleukin 6 (Interferon, beta 2).	0.684
HAMP	IL6-2	ENSPTRP00000018553	ENSPTRP00000080270	Hepcidin antimicrobial peptide.	Interleukin 6.	0.684
HAMP	TFRC	ENSPTRP00000018553	ENSPTRP00000046807	Hepcidin antimicrobial peptide.	Transferrin receptor (P90, CD71).	0.796
IL6	CCN2	ENSPTRP00000068252	ENSPTRP00000090133	Interleukin 6 (Interferon, beta 2).	CTGF isoform 1.	0.481
IL6	CD4	ENSPTRP00000068252	ENSPTRP00000054833	Interleukin 6 (Interferon, beta 2).	T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...]	0.897
IL6	GOT2	ENSPTRP00000068252	ENSPTRP00000013976	Interleukin 6 (Interferon, beta 2).	Aspartate aminotransferase.	0.443
IL6	HAMP	ENSPTRP00000068252	ENSPTRP00000018553	Interleukin 6 (Interferon, beta 2).	Hepcidin antimicrobial peptide.	0.684
IL6	IL6-2	ENSPTRP00000068252	ENSPTRP00000080270	Interleukin 6 (Interferon, beta 2).	Interleukin 6.	0.543
IL6-2	CCN2	ENSPTRP00000080270	ENSPTRP00000090133	Interleukin 6.	CTGF isoform 1.	0.481
IL6-2	CD4	ENSPTRP00000080270	ENSPTRP00000054833	Interleukin 6.	T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...]	0.897
IL6-2	GOT2	ENSPTRP00000080270	ENSPTRP00000013976	Interleukin 6.	Aspartate aminotransferase.	0.443