STRINGSTRING
NCAM1 NCAM1 PLXNA4 PLXNA4 ACTB ACTB PLXNA3 PLXNA3 GADD45G GADD45G SEMA3A SEMA3A CDC25B CDC25B NRP1 NRP1 TUBB TUBB PLXNA2 PLXNA2 GLUL GLUL TBR1 TBR1 PLXNA1 PLXNA1 FGF2 FGF2 DCX DCX SLC1A2 SLC1A2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NCAM1Neural cell adhesion molecule 1. (884 aa)
PLXNA4PLXNA4 isoform 1. (1894 aa)
ACTBActin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. (378 aa)
PLXNA3PLXNA3 isoform 1. (1871 aa)
GADD45GGrowth arrest and DNA-damage-inducible, gamma. (159 aa)
SEMA3ASEMA3A isoform 1; Belongs to the semaphorin family. (771 aa)
CDC25BCell division cycle 25 homolog B. (580 aa)
NRP1Neuropilin; Belongs to the neuropilin family. (923 aa)
TUBBTubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain; Belongs to the tubulin family. (444 aa)
PLXNA2PLXNA2 isoform 1. (1909 aa)
GLULGlutamine synthetase. (373 aa)
TBR1T-box brain transcription factor 1. (682 aa)
PLXNA1PLXNA1 isoform 1. (1915 aa)
FGF2Fibroblast growth factor 2; Acts as a ligand for FGFR1, FGFR2, FGFR3 and FGFR4. Also acts as an integrin ligand which is required for FGF2 signaling. Binds to integrin ITGAV:ITGB3. Plays an important role in the regulation of cell survival, cell division, cell differentiation and cell migration. Functions as a potent mitogen in vitro. Can induce angiogenesis. (288 aa)
DCXDCX isoform 5. (420 aa)
SLC1A2Amino acid transporter. (574 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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