29 items (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	RBM15	RNA binding motif protein 15. (977 aa)
	VCAM1	Vascular cell adhesion molecule 1. (650 aa)
	TRNP1	TMF1-regulated nuclear protein 1. (227 aa)
	CTCF	CCCTC-binding factor (Zinc finger protein). (727 aa)
	FOXP1	FOXP1 isoform 2. (693 aa)
	FOXP2	Forkhead box protein P2; Transcriptional repressor that may play a role in the specification and differentiation of lung epithelium. May also play a role in developing neural, gastrointestinal and cardiovascular tissues. Can act with CTBP1 to synergistically repress transcription but CTPBP1 is not essential. Plays a role in synapse formation by regulating SRPX2 levels (By similarity). (741 aa)
	HOPX	HOPX isoform 3. (112 aa)
	PAX6	PAX6 isoform 13. (436 aa)
	KIF18A	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (898 aa)
	STAU2	Staufen, RNA binding protein, homolog 2. (576 aa)
	EMX1	Empty spiracles homeobox 1. (290 aa)
	TBR1	T-box brain transcription factor 1. (682 aa)
	GLI2	GLI family zinc finger 2. (1587 aa)
	CK820_G0018745	FZD8 isoform 1; Belongs to the G-protein coupled receptor Fz/Smo family. (628 aa)
	DLX1	Distal-less homeobox 1. (255 aa)
	PPP1R17	Protein phosphatase 1 regulatory subunit 17. (155 aa)
	DLL1	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (723 aa)
	EGF	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1207 aa)
	NOVA1	NOVA alternative splicing regulator 1. (507 aa)
	SHH	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (465 aa)
	NOTCH2	NOTCH2 isoform 1. (2612 aa)
	PTBP1	PTBP1 isoform 2. (680 aa)
	DROSHA	Drosha, ribonuclease type III. (1380 aa)
	SATB2	DNA-binding protein SATB. (733 aa)
	TKTL1	TKTL1 isoform 3. (598 aa)
	PTBP2	Polypyrimidine tract binding protein 2. (543 aa)
	MEF2C	Myocyte enhancer factor 2C. (483 aa)
	GSX1	GSX1 isoform 1. (264 aa)
	EMX2	Empty spiracles homeobox 2. (252 aa)

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DLL1	EGF	ENSPTRP00000032142	ENSPTRP00000028112	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	0.463
DLL1	NOTCH2	ENSPTRP00000032142	ENSPTRP00000075807	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	NOTCH2 isoform 1.	0.994
DLL1	PAX6	ENSPTRP00000032142	ENSPTRP00000065705	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	PAX6 isoform 13.	0.429
DLL1	SATB2	ENSPTRP00000032142	ENSPTRP00000080249	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	DNA-binding protein SATB.	0.419
DLL1	SHH	ENSPTRP00000032142	ENSPTRP00000075730	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.411
DLX1	EMX1	ENSPTRP00000039172	ENSPTRP00000057829	Distal-less homeobox 1.	Empty spiracles homeobox 1.	0.423
DLX1	HOPX	ENSPTRP00000039172	ENSPTRP00000065973	Distal-less homeobox 1.	HOPX isoform 3.	0.458
DLX1	TBR1	ENSPTRP00000039172	ENSPTRP00000046292	Distal-less homeobox 1.	T-box brain transcription factor 1.	0.489
DROSHA	STAU2	ENSPTRP00000076963	ENSPTRP00000064136	Drosha, ribonuclease type III.	Staufen, RNA binding protein, homolog 2.	0.690
EGF	DLL1	ENSPTRP00000028112	ENSPTRP00000032142	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.463
EGF	PAX6	ENSPTRP00000028112	ENSPTRP00000065705	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	PAX6 isoform 13.	0.469
EGF	SHH	ENSPTRP00000028112	ENSPTRP00000075730	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.639
EGF	VCAM1	ENSPTRP00000028112	ENSPTRP00000001735	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	Vascular cell adhesion molecule 1.	0.457
EMX1	DLX1	ENSPTRP00000057829	ENSPTRP00000039172	Empty spiracles homeobox 1.	Distal-less homeobox 1.	0.423
EMX1	PAX6	ENSPTRP00000057829	ENSPTRP00000065705	Empty spiracles homeobox 1.	PAX6 isoform 13.	0.416
EMX1	SATB2	ENSPTRP00000057829	ENSPTRP00000080249	Empty spiracles homeobox 1.	DNA-binding protein SATB.	0.475
EMX1	TBR1	ENSPTRP00000057829	ENSPTRP00000046292	Empty spiracles homeobox 1.	T-box brain transcription factor 1.	0.690
EMX2	SHH	ENSPTRP00000005259	ENSPTRP00000075730	Empty spiracles homeobox 2.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.513
EMX2	TBR1	ENSPTRP00000005259	ENSPTRP00000046292	Empty spiracles homeobox 2.	T-box brain transcription factor 1.	0.605
FOXP1	FOXP2	ENSPTRP00000075187	ENSPTRP00000071606	FOXP1 isoform 2.	Forkhead box protein P2; Transcriptional repressor that may play a role in the specification and differentiation of lung epithelium. May also play a role in developing neural, gastrointestinal and cardiovascular tissues. Can act with CTBP1 to synergistically repress transcription but CTPBP1 is not essential. Plays a role in synapse formation by regulating SRPX2 levels (By similarity).	0.785