STRINGSTRING
LOC112209457 LOC112209457 MTOR MTOR H3-4 H3-4 TUB TUB NOG NOG HIST1H3A HIST1H3A ARL13B ARL13B TBR1 TBR1 SOX2 SOX2 H3C13 H3C13 FOXG1 FOXG1 PAX6 PAX6 FGF2 FGF2 CROCC CROCC SHH SHH IFT20 IFT20 LOC107966300 LOC107966300 NEUROD2 NEUROD2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC112209457HIST1H3A isoform 1. (136 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2549 aa)
H3-4HIST3H3 isoform 1. (136 aa)
TUBTubby-like protein; Belongs to the TUB family. (561 aa)
NOGNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
HIST1H3AH3F3B isoform 13. (136 aa)
ARL13BADP ribosylation factor like GTPase 13B. (428 aa)
TBR1T-box brain transcription factor 1. (682 aa)
SOX2SRY-box transcription factor 2. (319 aa)
H3C13HIST2H3A isoform 1. (136 aa)
FOXG1FOXG1 isoform 8. (489 aa)
PAX6PAX6 isoform 13. (436 aa)
FGF2Fibroblast growth factor 2; Acts as a ligand for FGFR1, FGFR2, FGFR3 and FGFR4. Also acts as an integrin ligand which is required for FGF2 signaling. Binds to integrin ITGAV:ITGB3. Plays an important role in the regulation of cell survival, cell division, cell differentiation and cell migration. Functions as a potent mitogen in vitro. Can induce angiogenesis. (288 aa)
CROCCCROCC isoform 1. (2017 aa)
SHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (465 aa)
IFT20IFT20 isoform 5. (164 aa)
LOC107966300Histone H3. (136 aa)
NEUROD2Neurogenic differentiation factor. (382 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.