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FADS2 | Fatty acid desaturase 2. (444 aa) | ||||
HPX | Hemopexin; Binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation. (462 aa) | ||||
SIRT1 | SIRT1 isoform 2. (751 aa) | ||||
PTGS2 | Prostaglandin-endoperoxide synthase 2 (Prostaglandin G/H synthase and cyclooxygenase). (604 aa) | ||||
SLC16A1 | Solute carrier family 16, member 1 (Monocarboxylic acid transporter 1). (500 aa) | ||||
TMSB4X-2 | Thymosin beta; Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization. Belongs to the thymosin beta family. (54 aa) | ||||
SESN2 | SESN2 isoform 1. (480 aa) | ||||
MFN2 | MFN2 isoform 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (757 aa) | ||||
POR-2 | NADPH--cytochrome P450 reductase; This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5; In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (680 aa) | ||||
SIRT1-2 | Sirtuin 1. (751 aa) | ||||
STAT3 | Signal transducer and activator of transcription. (790 aa) | ||||
PXDN | Peroxidasin homolog. (1479 aa) | ||||
SMAD3 | Mothers against decapentaplegic homolog. (442 aa) | ||||
FDFT1 | Farnesyl-diphosphate farnesyltransferase 1. (468 aa) | ||||
HJV | HFE2 isoform 1. (426 aa) | ||||
FXN | FXN isoform 1. (210 aa) | ||||
FTH1 | Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. (183 aa) | ||||
TIMP1 | TIMP metallopeptidase inhibitor 1. (207 aa) | ||||
BMP4-2 | Bone morphogenetic protein 4. (408 aa) | ||||
IL6-2 | Interleukin 6. (234 aa) | ||||
ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5. (1437 aa) | ||||
HFE | Hereditary hemochromatosis protein homolog; Binds to transferrin receptor (TFR) and reduces its affinity for iron-loaded transferrin. (348 aa) | ||||
LIFR | Leukemia inhibitory factor receptor alpha. (1097 aa) | ||||
ENSPTRP00000078404 | annotation not available (801 aa) | ||||
INS | Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (200 aa) | ||||
HMGCR | 3-hydroxy-3-methylglutaryl coenzyme A reductase. (888 aa) | ||||
ELAVL1 | ELAV-like protein; Belongs to the RRM elav family. (326 aa) | ||||
HMGB1 | HMGB1 isoform 1. (215 aa) | ||||
LPIN1 | LPIN1 isoform 7. (975 aa) | ||||
LEP | Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways (By similarity). In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo-pituitary-adrenal hormones. In the periphery, inc [...] (167 aa) | ||||
NF2 | Neurofibromin 2 (Merlin). (595 aa) | ||||
SLC3A2 | Solute carrier family 3 member 2. (631 aa) | ||||
TNF | Tumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] (234 aa) | ||||
SLC46A1 | Solute carrier family 46 (Folate transporter), member 1. (459 aa) | ||||
IL6 | Interleukin 6 (Interferon, beta 2). (234 aa) | ||||
SLC7A11 | Solute carrier family 7, (Cationic amino acid transporter, y+ system) member 11. (515 aa) | ||||
POR-3 | Cytochrome p450 oxidoreductase. (660 aa) | ||||
HP | HP isoform 15. (92 aa) | ||||
PCBP2 | Poly(rC) binding protein 2. (366 aa) | ||||
SMAD2 | Mothers against decapentaplegic homolog. (467 aa) | ||||
CYTB | Cytochrome b; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis. (380 aa) | ||||
GCH1 | GTP cyclohydrolase 1. (250 aa) | ||||
ADAM17 | ADAM17 isoform 3. (999 aa) | ||||
APOB | APOB isoform 1. (4562 aa) | ||||
GPX4 | Glutathione peroxidase; Belongs to the glutathione peroxidase family. (233 aa) | ||||
ECH1 | Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial isoform X1. (328 aa) | ||||
ACSL4 | Acyl-CoA synthetase long-chain family member 4. (749 aa) | ||||
FTHL17 | Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. (183 aa) | ||||
TLR4 | Toll-like receptor 4; Belongs to the Toll-like receptor family. (839 aa) | ||||
PXDNL | PXDNL isoform 2. (1463 aa) | ||||
IDO1 | IDO1 isoform 2. (403 aa) | ||||
TFR2 | Transferrin receptor 2. (801 aa) | ||||
BMPER | BMP binding endothelial regulator. (685 aa) | ||||
BMP6 | Bone morphogenetic protein 6. (512 aa) | ||||
FGFR4 | Fibroblast growth factor receptor. (802 aa) | ||||
LOX | LOX isoform 1. (417 aa) | ||||
FBXL5 | F-box and leucine-rich repeat protein 5. (691 aa) | ||||
STEAP3 | STEAP3 metalloreductase. (498 aa) | ||||
HAMP | Hepcidin antimicrobial peptide. (84 aa) | ||||
GDF15 | Growth differentiation factor 15. (308 aa) | ||||
KEAP1 | Kelch-like ECH-associated protein 1. (624 aa) | ||||
SMAD4 | Mothers against decapentaplegic homolog. (552 aa) | ||||
PIEZO1 | Piezo-type mechanosensitive ion channel component. (2516 aa) | ||||
DHODH | Dihydroorotate dehydrogenase (quinone), mitochondrial; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. (395 aa) | ||||
MT1G | Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals. (61 aa) | ||||
BMP4 | Bone morphogenetic protein 4. (408 aa) | ||||
IFNG | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons (By similarity). (166 aa) | ||||
NFE2 | Nuclear factor, erythroid 2. (373 aa) | ||||
PRDX5 | Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily. (214 aa) |