(9 nodes) (2023) Long noncoding RNA ENST00000436340 promotes podocyte injury in diabetic kidney disease by facilitating the association of PTBP1 with RAB3B. network (Pan troglodytes)

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Your Input:
	ACTB	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. (378 aa)
	RAB3B	RAB3B, member RAS oncogene family. (219 aa)
	GAPDH	Glyceraldehyde-3-phosphate dehydrogenase. (335 aa)
	PXDNL	PXDNL isoform 2. (1463 aa)
	SYNPO	SYNPO isoform 4. (899 aa)
	ALB	ALB isoform 2. (609 aa)
	PTBP1	PTBP1 isoform 2. (680 aa)
	INS	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (200 aa)
	PXDN	Peroxidasin homolog. (1479 aa)

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACTB	ALB	ENSPTRP00000058292	ENSPTRP00000056218	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.	ALB isoform 2.	0.755
ACTB	GAPDH	ENSPTRP00000058292	ENSPTRP00000007822	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.	Glyceraldehyde-3-phosphate dehydrogenase.	0.896
ACTB	INS	ENSPTRP00000058292	ENSPTRP00000077843	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.555
ACTB	PXDN	ENSPTRP00000058292	ENSPTRP00000090912	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.	Peroxidasin homolog.	0.855
ACTB	PXDNL	ENSPTRP00000058292	ENSPTRP00000034664	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.	PXDNL isoform 2.	0.855
ACTB	SYNPO	ENSPTRP00000058292	ENSPTRP00000047044	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.	SYNPO isoform 4.	0.933
ALB	ACTB	ENSPTRP00000056218	ENSPTRP00000058292	ALB isoform 2.	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.	0.755
ALB	GAPDH	ENSPTRP00000056218	ENSPTRP00000007822	ALB isoform 2.	Glyceraldehyde-3-phosphate dehydrogenase.	0.785
ALB	INS	ENSPTRP00000056218	ENSPTRP00000077843	ALB isoform 2.	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.799
ALB	PXDN	ENSPTRP00000056218	ENSPTRP00000090912	ALB isoform 2.	Peroxidasin homolog.	0.854
ALB	PXDNL	ENSPTRP00000056218	ENSPTRP00000034664	ALB isoform 2.	PXDNL isoform 2.	0.854
GAPDH	ACTB	ENSPTRP00000007822	ENSPTRP00000058292	Glyceraldehyde-3-phosphate dehydrogenase.	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.	0.896
GAPDH	ALB	ENSPTRP00000007822	ENSPTRP00000056218	Glyceraldehyde-3-phosphate dehydrogenase.	ALB isoform 2.	0.785
GAPDH	INS	ENSPTRP00000007822	ENSPTRP00000077843	Glyceraldehyde-3-phosphate dehydrogenase.	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.604
GAPDH	PXDN	ENSPTRP00000007822	ENSPTRP00000090912	Glyceraldehyde-3-phosphate dehydrogenase.	Peroxidasin homolog.	0.848
GAPDH	PXDNL	ENSPTRP00000007822	ENSPTRP00000034664	Glyceraldehyde-3-phosphate dehydrogenase.	PXDNL isoform 2.	0.848
INS	ACTB	ENSPTRP00000077843	ENSPTRP00000058292	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.	0.555
INS	ALB	ENSPTRP00000077843	ENSPTRP00000056218	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	ALB isoform 2.	0.799
INS	GAPDH	ENSPTRP00000077843	ENSPTRP00000007822	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Glyceraldehyde-3-phosphate dehydrogenase.	0.604
INS	PXDN	ENSPTRP00000077843	ENSPTRP00000090912	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Peroxidasin homolog.	0.585