14 items (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	DKK1	Dickkopf-like protein 1. (289 aa)
	NEUROG2	NEUROG2 isoform 1. (272 aa)
	ASCL1	Achaete-scute family bHLH transcription factor 1. (232 aa)
	CALB2	CALB2 isoform 1. (271 aa)
	OLIG2	OLIG2 isoform 1. (323 aa)
	LRP5	Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1606 aa)
	PAX6	PAX6 isoform 13. (436 aa)
	CNTNAP2	Contactin associated protein like 2. (1331 aa)
	SHANK3	SHANK3 isoform 2. (1744 aa)
	TBR1	T-box brain transcription factor 1. (682 aa)
	DKK4	Dickkopf WNT signaling pathway inhibitor 4. (224 aa)
	DKK2	Dickkopf WNT signaling pathway inhibitor 2. (259 aa)
	SOX5	SRY (Sex determining region Y)-box 5. (765 aa)
	LRP6	Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1613 aa)

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ASCL1	CALB2	ENSPTRP00000077846	ENSPTRP00000071995	Achaete-scute family bHLH transcription factor 1.	CALB2 isoform 1.	0.412
ASCL1	NEUROG2	ENSPTRP00000077846	ENSPTRP00000084422	Achaete-scute family bHLH transcription factor 1.	NEUROG2 isoform 1.	0.833
ASCL1	OLIG2	ENSPTRP00000077846	ENSPTRP00000069533	Achaete-scute family bHLH transcription factor 1.	OLIG2 isoform 1.	0.578
ASCL1	PAX6	ENSPTRP00000077846	ENSPTRP00000065705	Achaete-scute family bHLH transcription factor 1.	PAX6 isoform 13.	0.590
ASCL1	TBR1	ENSPTRP00000077846	ENSPTRP00000046292	Achaete-scute family bHLH transcription factor 1.	T-box brain transcription factor 1.	0.473
CALB2	ASCL1	ENSPTRP00000071995	ENSPTRP00000077846	CALB2 isoform 1.	Achaete-scute family bHLH transcription factor 1.	0.412
CALB2	PAX6	ENSPTRP00000071995	ENSPTRP00000065705	CALB2 isoform 1.	PAX6 isoform 13.	0.606
CALB2	TBR1	ENSPTRP00000071995	ENSPTRP00000046292	CALB2 isoform 1.	T-box brain transcription factor 1.	0.641
CNTNAP2	SHANK3	ENSPTRP00000064715	ENSPTRP00000063533	Contactin associated protein like 2.	SHANK3 isoform 2.	0.525
DKK1	DKK2	ENSPTRP00000004327	ENSPTRP00000028083	Dickkopf-like protein 1.	Dickkopf WNT signaling pathway inhibitor 2.	0.955
DKK1	DKK4	ENSPTRP00000004327	ENSPTRP00000034605	Dickkopf-like protein 1.	Dickkopf WNT signaling pathway inhibitor 4.	0.945
DKK1	LRP5	ENSPTRP00000004327	ENSPTRP00000068813	Dickkopf-like protein 1.	Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family.	0.997
DKK1	LRP6	ENSPTRP00000004327	ENSPTRP00000008035	Dickkopf-like protein 1.	Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family.	0.999
DKK2	DKK1	ENSPTRP00000028083	ENSPTRP00000004327	Dickkopf WNT signaling pathway inhibitor 2.	Dickkopf-like protein 1.	0.955
DKK2	DKK4	ENSPTRP00000028083	ENSPTRP00000034605	Dickkopf WNT signaling pathway inhibitor 2.	Dickkopf WNT signaling pathway inhibitor 4.	0.931
DKK2	LRP5	ENSPTRP00000028083	ENSPTRP00000068813	Dickkopf WNT signaling pathway inhibitor 2.	Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family.	0.994
DKK2	LRP6	ENSPTRP00000028083	ENSPTRP00000008035	Dickkopf WNT signaling pathway inhibitor 2.	Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family.	0.993
DKK4	DKK1	ENSPTRP00000034605	ENSPTRP00000004327	Dickkopf WNT signaling pathway inhibitor 4.	Dickkopf-like protein 1.	0.945
DKK4	DKK2	ENSPTRP00000034605	ENSPTRP00000028083	Dickkopf WNT signaling pathway inhibitor 4.	Dickkopf WNT signaling pathway inhibitor 2.	0.931
DKK4	LRP5	ENSPTRP00000034605	ENSPTRP00000068813	Dickkopf WNT signaling pathway inhibitor 4.	Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family.	0.992