STRINGSTRING
LILRB4 LILRB4 CD1C CD1C FCER1A FCER1A IFITM3 IFITM3 IL18 IL18 CD3D CD3D KLRF1 KLRF1 IFNG IFNG IL22 IL22 CDR2 CDR2 CD79B CD79B CD79A CD79A NCR1 NCR1 GZMA GZMA TNFAIP3 TNFAIP3 FCN1 FCN1 TSC22D3 TSC22D3 MZB1 MZB1 CLEC10A CLEC10A CLEC4C CLEC4C LOC451223 LOC451223 XCR1 XCR1 CD4 CD4 KLRD1 KLRD1 TNF TNF DUSP2 DUSP2 GNLY GNLY NKG7 NKG7 LOC112204135 LOC112204135 JCHAIN JCHAIN GZMB GZMB ENSPTRP00000087608 ENSPTRP00000087608
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LILRB4LILRB4 isoform 7. (449 aa)
CD1CCD1C isoform 1. (333 aa)
FCER1AFCER1A isoform 1. (260 aa)
IFITM3Interferon induced transmembrane protein 3. (112 aa)
IL18Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family. (193 aa)
CD3DCD3D isoform 1. (171 aa)
KLRF1Killer cell lectin like receptor F1. (231 aa)
IFNGInterferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons (By similarity). (166 aa)
IL22IL22 isoform 1. (179 aa)
CDR2Cerebellar degeneration-related protein 2, 62kDa. (454 aa)
CD79BCD79B isoform 2. (230 aa)
CD79ACD79A isoform 1. (226 aa)
NCR1NCR1 isoform 1. (303 aa)
GZMAGZMA isoform 1; Belongs to the peptidase S1 family. (262 aa)
TNFAIP3Tumor necrosis factor, alpha-induced protein 3. (790 aa)
FCN1FCN1 isoform 2. (355 aa)
TSC22D3TSC22 domain family, member 3. (200 aa)
MZB1Marginal zone B and B1 cell specific protein. (189 aa)
CLEC10AC-type lectin domain containing 10A. (316 aa)
CLEC4CC-type lectin domain family 4 member C. (213 aa)
LOC451223MS4A1 isoform 1. (297 aa)
XCR1X-C motif chemokine receptor 1; Belongs to the G-protein coupled receptor 1 family. (333 aa)
CD4T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...] (458 aa)
KLRD1Natural killer cells antigen CD94; Plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. (179 aa)
TNFTumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] (234 aa)
DUSP2Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (314 aa)
GNLYGNLY isoform 8. (173 aa)
NKG7NKG7 isoform 2. (165 aa)
LOC112204135X-C motif chemokine ligand 1. (114 aa)
JCHAINJoining chain of multimeric IgA and IgM. (159 aa)
GZMBGZMB isoform 2; Belongs to the peptidase S1 family. (280 aa)
ENSPTRP00000087608annotation not available (303 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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