19 items (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	MMP9	Matrix metallopeptidase 9. (699 aa)
	HIST1H3A	H3F3B isoform 13. (136 aa)
	MAU2	MAU2 chromatid cohesion factor homolog. (621 aa)
	SOX9	Transcription factor SOX-9; Transcriptional regulator that plays a role in chondrocytes differentiation and skeletal development. Binds to the COL2A1 promoter and activates COL2A1 expression, as part of a complex with ZNF219. (509 aa)
	CTCF	CCCTC-binding factor (Zinc finger protein). (727 aa)
	OAF	Out at first homolog. (273 aa)
	CD34	CD34 isoform 1. (328 aa)
	H3-4	HIST3H3 isoform 1. (136 aa)
	SHH	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (465 aa)
	LOC107966300	Histone H3. (136 aa)
	CHIA	CHIA isoform 3; Belongs to the glycosyl hydrolase 18 family. (466 aa)
	GATA1	GATA binding protein 1. (413 aa)
	ATOH1	Protein atonal homolog 1; Transcriptional regulator. Activates E box-dependent transcription in collaboration with TCF3/E47, but the activity is completely antagonized by the negative regulator of neurogenesis HES1. Plays a role in the differentiation of subsets of neural cells by activating E box-dependent transcription (By similarity). (356 aa)
	WAPL	WAPL cohesin release factor. (1190 aa)
	H3C13	HIST2H3A isoform 1. (136 aa)
	NIPBL	Nipped-B protein. (2804 aa)
	BCL11A	BAF chromatin remodeling complex subunit BCL11A. (835 aa)
	LHX2	LHX2 isoform 1. (406 aa)
	LOC112209457	HIST1H3A isoform 1. (136 aa)

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATOH1	LHX2	ENSPTRP00000053413	ENSPTRP00000036487	Protein atonal homolog 1; Transcriptional regulator. Activates E box-dependent transcription in collaboration with TCF3/E47, but the activity is completely antagonized by the negative regulator of neurogenesis HES1. Plays a role in the differentiation of subsets of neural cells by activating E box-dependent transcription (By similarity).	LHX2 isoform 1.	0.478
ATOH1	SHH	ENSPTRP00000053413	ENSPTRP00000075730	Protein atonal homolog 1; Transcriptional regulator. Activates E box-dependent transcription in collaboration with TCF3/E47, but the activity is completely antagonized by the negative regulator of neurogenesis HES1. Plays a role in the differentiation of subsets of neural cells by activating E box-dependent transcription (By similarity).	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.602
BCL11A	GATA1	ENSPTRP00000042480	ENSPTRP00000086593	BAF chromatin remodeling complex subunit BCL11A.	GATA binding protein 1.	0.786
CD34	GATA1	ENSPTRP00000003262	ENSPTRP00000086593	CD34 isoform 1.	GATA binding protein 1.	0.669
CD34	MMP9	ENSPTRP00000003262	ENSPTRP00000023334	CD34 isoform 1.	Matrix metallopeptidase 9.	0.549
CD34	SOX9	ENSPTRP00000003262	ENSPTRP00000016293	CD34 isoform 1.	Transcription factor SOX-9; Transcriptional regulator that plays a role in chondrocytes differentiation and skeletal development. Binds to the COL2A1 promoter and activates COL2A1 expression, as part of a complex with ZNF219.	0.457
CHIA	CTCF	ENSPTRP00000081197	ENSPTRP00000014062	CHIA isoform 3; Belongs to the glycosyl hydrolase 18 family.	CCCTC-binding factor (Zinc finger protein).	0.716
CTCF	CHIA	ENSPTRP00000014062	ENSPTRP00000081197	CCCTC-binding factor (Zinc finger protein).	CHIA isoform 3; Belongs to the glycosyl hydrolase 18 family.	0.716
CTCF	GATA1	ENSPTRP00000014062	ENSPTRP00000086593	CCCTC-binding factor (Zinc finger protein).	GATA binding protein 1.	0.539
CTCF	H3-4	ENSPTRP00000014062	ENSPTRP00000002098	CCCTC-binding factor (Zinc finger protein).	HIST3H3 isoform 1.	0.621
CTCF	H3C13	ENSPTRP00000014062	ENSPTRP00000048353	CCCTC-binding factor (Zinc finger protein).	HIST2H3A isoform 1.	0.556
CTCF	HIST1H3A	ENSPTRP00000014062	ENSPTRP00000021631	CCCTC-binding factor (Zinc finger protein).	H3F3B isoform 13.	0.544
CTCF	LOC107966300	ENSPTRP00000014062	ENSPTRP00000078706	CCCTC-binding factor (Zinc finger protein).	Histone H3.	0.556
CTCF	LOC112209457	ENSPTRP00000014062	ENSPTRP00000030412	CCCTC-binding factor (Zinc finger protein).	HIST1H3A isoform 1.	0.435
CTCF	NIPBL	ENSPTRP00000014062	ENSPTRP00000048198	CCCTC-binding factor (Zinc finger protein).	Nipped-B protein.	0.728
CTCF	WAPL	ENSPTRP00000014062	ENSPTRP00000050569	CCCTC-binding factor (Zinc finger protein).	WAPL cohesin release factor.	0.592
GATA1	BCL11A	ENSPTRP00000086593	ENSPTRP00000042480	GATA binding protein 1.	BAF chromatin remodeling complex subunit BCL11A.	0.786
GATA1	CD34	ENSPTRP00000086593	ENSPTRP00000003262	GATA binding protein 1.	CD34 isoform 1.	0.669
GATA1	CTCF	ENSPTRP00000086593	ENSPTRP00000014062	GATA binding protein 1.	CCCTC-binding factor (Zinc finger protein).	0.539
GATA1	H3-4	ENSPTRP00000086593	ENSPTRP00000002098	GATA binding protein 1.	HIST3H3 isoform 1.	0.576